Update on Guidelines for the Management of Cancer‐Associated Thrombosis

Cancer‐associated thrombosis (CAT) is a major cause of morbidity and mortality in patients with cancer. Over the past 2 decades, enormous advances have been made in the management of CAT. The growing evidence base informing practice has led to the publication of a number of guidelines and guidance d...

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Vydáno v:The oncologist (Dayton, Ohio) Ročník 26; číslo 1; s. e24 - e40
Hlavní autoři: Streiff, Michael B., Abutalib, Syed Ali, Farge, Dominique, Murphy, Martina, Connors, Jean M., Piazza, Gregory
Médium: Journal Article
Jazyk:angličtina
Vydáno: Hoboken, USA John Wiley & Sons, Inc 01.01.2021
Oxford University Press
Témata:
Analysis
Anticoagulants (Medicine)
Blood clot
Cancer
Cancer‐associated thrombosis
Care and treatment
Complications and side effects
Evaluation
Evidence-based medicine
France
Guideline
Health aspects
Management
Management science
Mortality
Practice guidelines (Medicine)
Prevention
Risk factors
Special Series: Approach to the Patient with Cancer and Thrombosis
Thrombosis
Treatment
Web applications
United States
France
Prevention
Guideline
Treatment
Management
Cancer-associated thrombosis
ISSN:1083-7159, 1549-490X, 1549-490X
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Shrnutí:Cancer‐associated thrombosis (CAT) is a major cause of morbidity and mortality in patients with cancer. Over the past 2 decades, enormous advances have been made in the management of CAT. The growing evidence base informing practice has led to the publication of a number of guidelines and guidance documents on the diagnosis and treatment of CAT. The goal of this review is to examine the latest versions of evidence‐based guidelines, highlighting the differences and similarities in their methodology, their disease‐specific content, and recommendations for management. Our analysis shows that for most clinical topics, the different guidelines provide roughly similar management advice. However, there are a number of important clinical topics in CAT that are not currently covered by the existing guidelines. We think inclusion of these topics in future versions of the guidelines will facilitate ongoing efforts to optimize the care of patients with CAT. Implications for Practice Cancer‐associated thrombosis (CAT) is a common complication in patients with cancer. This review examines the differences and similarities of the current CAT guidelines methods and recommendations. Current guidelines largely agree on many aspects of CAT management. However, there are a number of topics in CAT that are not currently included in guidelines where evidence‐based guidance would be very helpful for clinicians. Coverage of these topics in future guidelines is encouraged to optimize clinical practice. Numerous guidelines for cancer‐associated thromboembolism have been published. This review compares recommendations from the most recent cancer‐specific guidelines, identifying areas in which guidance is lacking.
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Disclosures of potential conflicts of interest may be found at the end of this article
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Disclosures of potential conflicts of interest may be found at the end of this article.
No part of this article may be reproduced, stored, or transmitted in any form or for any means without the prior permission in writing from the copyright holder. For information on purchasing reprints contact commercialreprints@wiley.com. For permission information contact permissions@wiley.com.
ISSN:1083-7159
1549-490X
1549-490X
DOI:10.1002/onco.13596