Oxidative Stress in Kidney Injury and Hypertension

Hypertension (HTN) is a major contributor to kidney damage, leading to conditions such as nephrosclerosis and hypertensive nephropathy, significant causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD). HTN is also a risk factor for stroke and coronary heart disease. Oxidative st...

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Bibliographic Details
Published in:	Antioxidants Vol. 13; no. 12; p. 1454
Main Authors:	Arendshorst, Willaim J., Vendrov, Aleksandr E., Kumar, Nitin, Ganesh, Santhi K., Madamanchi, Nageswara R.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.12.2024 MDPI
Subjects:	African Americans Aldosterone Analysis Angiotensin Angiotensin II Angiotensin II receptors Animal models Antihypertensives Antioxidants Apoptosis Blood pressure Cardiovascular disease Chronic kidney failure Collagen Coronary artery disease Coronary heart disease Diabetes Diseases End-stage renal disease Energy metabolism Environmental factors Enzymes Genetic aspects Genetic diversity Heart diseases Hypertension Inflammation Injuries Intestinal microflora Isoforms Kidney diseases Kinases mitochondrial dysfunction NAD(P)H oxidase NADPH oxidases Nephropathy Oxidases Oxidative stress Patients Physiological aspects Proteins Reactive oxygen species redox-sensitive signaling pathways Renal function Renin Review Risk factors ROS Stroke (Disease) United States United States chronic kidney disease Nrf2/ARE pathway NADPH oxidases antioxidants TGF-β signaling mitochondrial dysfunction renal dysfunction vascular remodeling MR receptor antagonists NF-κB signaling inflammation angiotensin II ROS renin–angiotensin–aldosterone system (RAAS) redox-sensitive signaling pathways fibrosis hypertension oxidative stress SGLT2 inhibitors
ISSN:	2076-3921, 2076-3921
Online Access:	Get full text
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