Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial

ABSTRACT Background Epidemiological studies have shown that increased circulating branched-chain amino acids (BCAAs) are associated with insulin resistance and type 2 diabetes (T2D). This may result from altered energy metabolism or dietary habits. Objective We hypothesized that a lower intake of BC...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of clinical nutrition Jg. 110; H. 5; S. 1098 - 1107
Hauptverfasser:	Karusheva, Yanislava, Koessler, Theresa, Strassburger, Klaus, Markgraf, Daniel, Mastrototaro, Lucia, Jelenik, Tomas, Simon, Marie-Christine, Pesta, Dominik, Zaharia, Oana-Patricia, Bódis, Kálmán, Bärenz, Felix, Schmoll, Dieter, Wolkersdorfer, Martin, Tura, Andrea, Pacini, Giovanni, Burkart, Volker, Müssig, Karsten, Szendroedi, Julia, Roden, Michael
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Oxford University Press 01.11.2019
Schlagworte:	Adipose Tissue, White - metabolism Amino Acids, Branched-Chain - administration & dosage Cross-Over Studies Diabetes Mellitus, Type 2 - microbiology Double-Blind Method Female Gastrointestinal Microbiome Humans Insulin Secretion Male Meals Middle Aged Mitochondria - physiology Muscle, Skeletal - metabolism insulin sensitivity mitochondrial function gut microbiome patients with type 2 diabetes diet insulin secretion branched-chain amino acids
ISSN:	0002-9165, 1938-3207, 1938-3207
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!