Cells susceptible to epithelial-mesenchymal transition are enriched in stem-like side population cells from prostate cancer

Accumulating evidence suggests that epithelial-mesenchymal transition (EMT) acts as an important factor for the promotion of tumor progression. Strategies for suppressing EMT remain the subject of ongoing research. In the present study, fluorescence-activated cell sorting (FACS) was used to isolate...

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Bibliographic Details
Published in:	Oncology reports Vol. 31; no. 2; pp. 874 - 884
Main Authors:	LUO, YONG, CUI, XINHAO, ZHAO, JIAHUI, HAN, YILI, LI, MINGCHUAN, LIN, YUNHUA, JIANG, YONGGUANG, LAN, LING
Format:	Journal Article
Language:	English
Published:	Greece D.A. Spandidos 01.02.2014 Spandidos Publications Spandidos Publications UK Ltd
Subjects:	Actins - biosynthesis Analysis Animals beta Catenin - biosynthesis Biomarkers, Tumor - biosynthesis Bone Neoplasms - secondary Cadherins - biosynthesis cancer stem cells Care and treatment Cell Line, Tumor Cell Proliferation Cell Transformation, Neoplastic - genetics Chemotherapy China Cloning Comparative analysis Development and progression Epithelial-Mesenchymal Transition Fluorescence Gene Expression Regulation, Neoplastic Genotype & phenotype Health aspects heterogeneity Humans hypoxia inducible factor-1α Hypoxia-Inducible Factor 1, alpha Subunit - genetics Male Matrix Metalloproteinase 2 - biosynthesis Medical research Membranes Metastasis Mice Mice, Nude Mortality Neoplasm Invasiveness Neoplasm Transplantation Neoplastic Stem Cells - cytology Neoplastic Stem Cells - pathology Population Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Protein expression Proteins side population cells Side-Population Cells - cytology Side-Population Cells - pathology Stem cells Studies Transfection Transplantation, Heterologous Tumors Vimentin - biosynthesis China United States > US
ISSN:	1021-335X, 1791-2431, 1791-2431
Online Access:	Get full text
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