Targeting autophagy in cancer

Autophagy is a conserved, self‐degradation system that is critical for maintaining cellular homeostasis during stress conditions. Dysregulated autophagy has implications in health and disease. Specifically, in cancer, autophagy plays a dichotomous role by inhibiting tumor initiation but supporting t...

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Vydané v:	Cancer Ročník 124; číslo 16; s. 3307 - 3318
Hlavní autori:	Onorati, Angelique V., Dyczynski, Matheus, Ojha, Rani, Amaravadi, Ravi K.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Wiley Subscription Services, Inc 01.08.2018
Predmet:	Autophagy Autophagy - drug effects Autophagy - genetics Cancer Carcinogenesis - drug effects Carcinogenesis - genetics chemotherapy Clinical trials Drug Development Homeostasis Humans Hydroxychloroquine hydroxychloroquine (HCQ) Immunity Immunotherapy Literature reviews Medical research Molecular Targeted Therapy Neoplasms - drug therapy Neoplasms - epidemiology Neoplasms - genetics Oncology Phagocytosis Tumors hydroxychloroquine (HCQ) Autophagy chemotherapy immunotherapy
ISSN:	0008-543X, 1097-0142, 1097-0142
On-line prístup:	Získať plný text
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