Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study

Concern about possible false-negative prostate biopsy histopathology findings often leads to rebiopsy. A quantitative methylation specific polymerase chain reaction assay panel, including GSTP1, APC and RASSF1, could increase the sensitivity of detecting cancer over that of pathological review alone...

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Vydané v:	The Journal of urology Ročník 189; číslo 3; s. 1110
Hlavní autori:	Stewart, Grant D, Van Neste, Leander, Delvenne, Philippe, Delrée, Paul, Delga, Agnès, McNeill, S Alan, O'Donnell, Marie, Clark, James, Van Criekinge, Wim, Bigley, Joseph, Harrison, David J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.2013
Predmet:	Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Biopsy, Needle DNA, Neoplasm - analysis DNA, Neoplasm - genetics Epigenomics - methods Humans Male Polymerase Chain Reaction Prostate - metabolism Prostate - pathology Prostatic Neoplasms - diagnosis Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Retrospective Studies
ISSN:	1527-3792, 1527-3792
On-line prístup:	Zistit podrobnosti o prístupe
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