Enhancement of Hippocampal Neurogenesis by Lithium

: Increasing evidence suggests that mood disorders are associated with a reduction in regional CNS volume and neuronal and glial cell atrophy or loss. Lithium, a mainstay in the treatment of mood disorders, has recently been demonstrated to robustly increase the levels of the cytoprotective B‐cell l...

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Bibliographic Details
Published in:	Journal of neurochemistry Vol. 75; no. 4; pp. 1729 - 1734
Main Authors:	Chen, Guang, Rajkowska, Grazyna, Du, Fu, Seraji‐Bozorgzad, Navid, Manji, Husseini K.
Format:	Journal Article
Language:	English
Published:	Oxford UK Blackwell Science Ltd 01.10.2000 Blackwell
Subjects:	5‐Bromo‐2‐deoxyuridine Animals Antigens, Differentiation - metabolism bcl‐2 Biological and medical sciences Bromodeoxyuridine Cell Division - drug effects Hippocampus - cytology Hippocampus - drug effects Hippocampus - metabolism Immunohistochemistry Lithium Lithium - pharmacology Male Manic‐depressive illness Medical sciences Mice Mice, Inbred C57BL Nerve Regeneration - drug effects Neurogenesis Neurons - cytology Neurons - drug effects Neurons - metabolism Neuropharmacology Pharmacology. Drug treatments Phenotype Proto-Oncogene Proteins c-bcl-2 - metabolism Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Mood disorder Cell proliferation Rodentia Central nervous system Lithium Bipolar disorder Biological activity Vertebrata Chemotherapy Mammalia Treatment Mouse Hippocampus Brain (vertebrata)
ISSN:	0022-3042, 1471-4159
Online Access:	Get full text
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