The epidemiology of contact allergy in the general population - prevalence and main findings

A substantial number of studies have investigated the prevalence of contact allergy in the general population and in unselected subgroups of the general population. The aim of this review was to determine a median prevalence and summarize the main findings from studies on contact allergy in the gene...

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Podrobná bibliografia
Vydané v:Contact dermatitis Ročník 57; číslo 5; s. 287 - 299
Hlavní autori: Thyssen, Jacob Pontoppidan, Linneberg, Allan, Menné, Torkil, Johansen, Jeanne Duus
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Oxford, UK Blackwell Publishing Ltd 01.11.2007
Blackwell
Predmet:
Allergic diseases
Biological and medical sciences
Chemical and industrial products toxicology. Toxic occupational diseases
contact allergy
contact dermatitis
Dermatitis, Allergic Contact - epidemiology
Dermatitis, Allergic Contact - etiology
epidemic
Europe - epidemiology
healthy
Humans
Immunopathology
Medical sciences
Metals and various inorganic compounds
nickel
North America - epidemiology
Population Surveillance
Prevalence
Skin allergic diseases. Stinging insect allergies
Toxicology
unselected
North America
Europe
Human
Immunopathology
Allergy
Skin disease
Prevalence
epidemic
unselected
Review
Epidemiology
Heavy metal
contact allergy
Contact dermatitis
healthy
Nickel
Bibliographic review
ISSN:0105-1873, 1600-0536
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Shrnutí:A substantial number of studies have investigated the prevalence of contact allergy in the general population and in unselected subgroups of the general population. The aim of this review was to determine a median prevalence and summarize the main findings from studies on contact allergy in the general population. Published research mainly originates from North America and Western Europe. The median prevalence of contact allergy to at least 1 allergen was 21.2% (range 12.5–40.6%), and the weighted average prevalence was 19.5%, based on data collected on all age groups and all countries between 1966 and 2007. The most prevalent contact allergens were nickel, thimerosal, and fragrance mix. The median nickel allergy prevalence was 8.6% (range 0.7–27.8%) and demonstrates that nickel was an important cause of contact allergy in the general population and that it was widespread in both men and women. Numerous studies demonstrated that pierced ears were a significant risk factor for nickel allergy. Nickel was a risk factor for hand eczema in women. Finally, heavy smoking was associated with contact allergy, mostly in women. Population‐based epidemiological studies are considered a prerequisite in the surveillance of national and international contact allergy epidemics.
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content type line 23
ISSN:0105-1873
1600-0536
DOI:10.1111/j.1600-0536.2007.01220.x