Microarray data and pathway analyses of peripheral blood mononuclear cells from healthy subjects after a three weeks grape-rich diet

Using Human Gene Expression Microarrays (Agilent) technologies, we investigated changes of the level of gene expression in peripheral blood mononuclear cells of healthy subjects after 21 days of fresh table grape-rich diet and after an additional 28-day washout. Several hundreds of genes were differ...

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Vydané v:Data in brief Ročník 29; s. 105278
Hlavní autori: Milella, Rosa Anna, Gasparro, Marica, Alagna, Fiammetta, Cardone, Maria Francesca, Rotunno, Silvia, Ammollo, Concetta Tiziana, Semeraro, Fabrizio, Tullo, Apollonia, Marzano, Flaviana, Catalano, Domenico, Antonacci, Donato, Colucci, Mario, D'Elia, Domenica
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Netherlands Elsevier Inc 01.04.2020
Elsevier
Predmet:
autophagy
Biochemistry, Genetics and Molecular Biology
biogenesis
Biological processes
diet
Diets
DNA
gene expression
Grape intake
grapes
Health benefits
Human health
humans
immunity
inflammation
Microarray data
microarray technology
mitochondria
non-coding RNA
nutrigenomics
Pathway analyses
Peripheral blood mononuclear cells
thrombosis
Diets
Grape intake
Human health
Pathway analyses
Microarray data
Biological processes
Peripheral blood mononuclear cells
Health benefits
ISSN:2352-3409, 2352-3409
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Shrnutí:Using Human Gene Expression Microarrays (Agilent) technologies, we investigated changes of the level of gene expression in peripheral blood mononuclear cells of healthy subjects after 21 days of fresh table grape-rich diet and after an additional 28-day washout. Several hundreds of genes were differentially expressed after grape intake or after washout. The functional analysis of these genes detected significant changes in key processes such as inflammation and immunity, thrombosis, DNA and protein repair, autophagy and mitochondrial biogenesis. Moreover, fresh grape intake was found to influence the expression of many long non-coding RNA genes. The data can be valuable for researchers interested in nutrigenetics and nutrigenomics studies and are related to the research article “Gene expression signature induced by grape intake in healthy subjects reveals wide-spread beneficial effects on PBMCs” [1].
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Present address: ENEA Italian National Agency for New Technologies Energy and Sustainable Economic Development,Trisaia Research Center, Rotondella, 75026, Matera, Italy.
Present address: Department of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Italy.
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2020.105278