Transgenic pigs carrying cDNA copies encoding the murine Mx1 protein which confers resistance to influenza virus infection

An important aspect of gene transfer into farm animals is the improvement of disease resistance. The mouse Mx1 protein is known to be sufficient to confer resistance to influenza viruses. Gene constructs containing the mouse Mx1 cDNA controlled by the human metallothionein IIA promoter (hMTIIA::Mx),...

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Bibliographic Details
Published in:	Gene Vol. 121; no. 2; p. 263
Main Authors:	Müller, M, Brenig, B, Winnacker, E L, Brem, G
Format:	Journal Article
Language:	English
Published:	Netherlands 16.11.1992
Subjects:	Animals Animals, Genetically Modified Antiviral Agents DNA - genetics Gene Expression GTP-Binding Proteins Immunity, Innate Mice Myxovirus Resistance Proteins Orthomyxoviridae Infections - genetics Orthomyxoviridae Infections - prevention & control Orthomyxoviridae Infections - veterinary Promoter Regions, Genetic Proteins - genetics Recombinant Proteins - metabolism RNA, Messenger - genetics Swine
ISSN:	0378-1119
Online Access:	Get more information
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