Transgenic pigs carrying cDNA copies encoding the murine Mx1 protein which confers resistance to influenza virus infection

An important aspect of gene transfer into farm animals is the improvement of disease resistance. The mouse Mx1 protein is known to be sufficient to confer resistance to influenza viruses. Gene constructs containing the mouse Mx1 cDNA controlled by the human metallothionein IIA promoter (hMTIIA::Mx),...

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Bibliographische Detailangaben
Veröffentlicht in:	Gene Jg. 121; H. 2; S. 263
Hauptverfasser:	Müller, M, Brenig, B, Winnacker, E L, Brem, G
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands 16.11.1992
Schlagworte:	Animals Animals, Genetically Modified Antiviral Agents DNA - genetics Gene Expression GTP-Binding Proteins Immunity, Innate Mice Myxovirus Resistance Proteins Orthomyxoviridae Infections - genetics Orthomyxoviridae Infections - prevention & control Orthomyxoviridae Infections - veterinary Promoter Regions, Genetic Proteins - genetics Recombinant Proteins - metabolism RNA, Messenger - genetics Swine
ISSN:	0378-1119
Online-Zugang:	Weitere Angaben
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