Angiotensin Converting Enzyme 2 May Mediate Disease Severity In COVID-19

[...]we propose that measurement of ACE2 level may help identify individuals at risk of severe infection where targeted shielding can be used and could provide a novel therapeutic target. The resultant increased sACE2 may act as a “dummy” receptor, binding the S protein on circulating virus. [...]hi...

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Vydáno v:	The American journal of cardiology Ročník 130; s. 161 - 162
Hlavní autoři:	Gue, Ying Xuan, Kanji, Rahim, Markides, Vias, Gorog, Diana Adrienne
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 01.09.2020 Elsevier Limited
Témata:	ACE2 Angiotensin Angiotensin-Converting Enzyme 2 Betacoronavirus Binding Coronavirus Infections - physiopathology Coronaviruses COVID-19 Enzymes Gene Expression Regulation Humans Hypertension Infections Kidney diseases Metabolic syndrome Pandemics Peptidyl-dipeptidase A Peptidyl-Dipeptidase A - genetics Pneumonia, Viral - physiopathology Proteins Receptors Risk Factors SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Shielding Viral diseases Viruses
ISSN:	0002-9149, 1879-1913, 1879-1913
On-line přístup:	Získat plný text
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