The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus

Metabolic syndrome is a frequent precursor of type 2 diabetes mellitus (T2D), a disease that currently affects ∼8% of the adult population worldwide. Pancreatic beta-cell dysfunction and loss are central to the disease process, although understanding of the underlying molecular mechanisms is still f...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Antioxidants & redox signaling Ročník 26; číslo 10; s. 501
Hlavní autori:	Gerber, Philipp A, Rutter, Guy A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.04.2017
Predmet:	Animals Antioxidants - metabolism Antioxidants - pharmacology Antioxidants - therapeutic use Diabetes Mellitus - etiology Diabetes Mellitus - metabolism Diabetes Mellitus - therapy Diabetes Mellitus, Type 2 - etiology Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - therapy Glucose - metabolism Humans Hypoxia - metabolism Insulin - metabolism Insulin-Secreting Cells - drug effects Insulin-Secreting Cells - metabolism Islets of Langerhans - metabolism Islets of Langerhans Transplantation Lipid Metabolism Mitochondria - metabolism Oxidative Stress Reactive Oxygen Species - metabolism Zinc - metabolism beta cell hypoxia insulin secretion diabetes zinc
ISSN:	1557-7716, 1557-7716
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!