Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous...
Saved in:
| Published in: | Science (American Association for the Advancement of Science) Vol. 344; no. 6182; p. 380 |
|---|---|
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
25.04.2014
|
| Subjects: | |
| ISSN: | 1095-9203, 1095-9203 |
| Online Access: | Get more information |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology. |
|---|---|
| AbstractList | Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology. Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24763584$$D View this record in MEDLINE/PubMed |
| BookMark | eNpNkM1Lw0AUxBep2A89e5M91kPqfmQ3ibdStAoFL3rwFDabF1xJdmveRuh_b4oVhIH3Bn4MzMzJxAcPhFxztuJc6Du0DryFFRdpoZU-IzPOCpUUgsnJv39K5oifjI2-kBdkKtJMS5WnM_K-BR86oAhfwzGJhobGD6ARYRRt2gNdbtuA6LyhXejRRePx9p5-g42hP-LrpnfWeBr7w974gKFzBh1ekvPGtAhXp7sgb48Pr5unZPeyfd6sd4lVaRaTRsgcsqrKlLUilarWRhoOXANnlR5LsZoLViuT5Zmq6wIYgwJUbqQyjRGNWJDlb-6-D2MHjGXn0ELbGg9hwJIrXggtc5GP6M0JHaoO6nLfu870h_JvDvEDuoFlIA |
| CitedBy_id | crossref_primary_10_1038_ismej_2014_236 crossref_primary_10_1093_genetics_iyad109 crossref_primary_10_1534_g3_119_400148 crossref_primary_10_1038_s41422_019_0252_6 crossref_primary_10_1186_s12866_018_1296_3 crossref_primary_10_1371_journal_ppat_1009475 crossref_primary_10_1016_j_cois_2015_12_002 crossref_primary_10_3389_fimmu_2016_00233 crossref_primary_10_1038_509011d crossref_primary_10_1371_journal_pntd_0009071 crossref_primary_10_3389_fmicb_2015_01259 crossref_primary_10_1111_1755_0998_13246 crossref_primary_10_1186_s13071_016_1714_z crossref_primary_10_3389_fphys_2022_831618 crossref_primary_10_1101_gr_234146_118 crossref_primary_10_3389_fevo_2018_00063 crossref_primary_10_7554_eLife_19535 crossref_primary_10_1371_journal_pgen_1008005 crossref_primary_10_1093_nsr_nwae245 crossref_primary_10_3390_pathogens7010032 crossref_primary_10_1186_s13059_019_1768_2 crossref_primary_10_1016_j_dci_2019_05_003 crossref_primary_10_1371_journal_pntd_0003376 crossref_primary_10_1371_journal_pntd_0002687 crossref_primary_10_1016_j_atg_2015_06_004 crossref_primary_10_1371_journal_pntd_0003895 crossref_primary_10_1186_s13104_020_05161_8 crossref_primary_10_1002_ps_5084 crossref_primary_10_1016_j_compbiolchem_2020_107347 crossref_primary_10_1186_s13071_022_05258_y crossref_primary_10_1371_journal_pbio_3000796 crossref_primary_10_1016_j_cois_2025_101369 crossref_primary_10_1093_icb_icad097 crossref_primary_10_1371_journal_ppat_1009904 crossref_primary_10_1038_nrmicro_2016_160 crossref_primary_10_1128_msystems_00140_25 crossref_primary_10_1371_journal_pone_0301274 crossref_primary_10_1093_molbev_msw101 crossref_primary_10_3390_pathogens8030135 crossref_primary_10_1186_s12915_021_01148_4 crossref_primary_10_1073_pnas_1907075116 crossref_primary_10_1111_rsp3_12090 crossref_primary_10_3389_fmicb_2020_01080 crossref_primary_10_1111_brv_12339 crossref_primary_10_1038_s41598_022_23550_w crossref_primary_10_1093_jisesa_ieac018 crossref_primary_10_1073_pnas_1720237115 crossref_primary_10_1371_journal_pntd_0010040 crossref_primary_10_1007_s10886_024_01527_5 crossref_primary_10_1007_s00360_014_0836_x crossref_primary_10_7717_peerj_4099 crossref_primary_10_1371_journal_pntd_0003515 crossref_primary_10_1016_j_ijbiomac_2024_136424 crossref_primary_10_1186_s12866_018_1278_5 crossref_primary_10_1016_j_jinsphys_2016_09_013 crossref_primary_10_1073_pnas_1821806116 crossref_primary_10_1093_jme_tjy018 crossref_primary_10_1371_journal_pntd_0006057 crossref_primary_10_1016_j_bbagrm_2019_04_008 crossref_primary_10_1016_j_neuron_2016_12_024 crossref_primary_10_1093_bioadv_vbab047 crossref_primary_10_1371_journal_pntd_0010833 crossref_primary_10_1371_journal_pcbi_1004308 crossref_primary_10_1016_j_actatropica_2016_01_009 crossref_primary_10_1016_j_actatropica_2017_08_032 crossref_primary_10_1038_s41467_021_23178_w crossref_primary_10_1111_ecaf_12121 crossref_primary_10_1111_mmi_12853 crossref_primary_10_1371_journal_pcbi_1004395 crossref_primary_10_3389_fmicb_2021_653880 crossref_primary_10_1111_evo_13863 crossref_primary_10_1186_s13071_022_05536_9 crossref_primary_10_1002_bies_201400200 crossref_primary_10_1016_j_cois_2014_07_003 crossref_primary_10_1038_s41598_020_76139_6 crossref_primary_10_1186_s12864_023_09474_3 crossref_primary_10_1371_journal_pntd_0004038 crossref_primary_10_3389_fmicb_2023_1151319 crossref_primary_10_1111_imb_12599 crossref_primary_10_1186_s12866_018_1294_5 crossref_primary_10_1186_s12866_018_1298_1 crossref_primary_10_1146_annurev_ento_020117_043447 crossref_primary_10_7554_eLife_31628 crossref_primary_10_1111_tmi_70031 crossref_primary_10_1371_journal_pntd_0008341 crossref_primary_10_3389_fmicb_2017_00540 crossref_primary_10_1186_s40168_017_0397_9 crossref_primary_10_1371_journal_ppat_1007412 crossref_primary_10_1186_s13059_016_0966_4 crossref_primary_10_3389_fendo_2020_00153 crossref_primary_10_1073_pnas_1423305112 crossref_primary_10_1155_2016_3164624 crossref_primary_10_1016_j_meegid_2015_04_023 crossref_primary_10_3390_insects14100802 crossref_primary_10_1146_annurev_ento_010814_020834 crossref_primary_10_1016_j_cois_2017_05_009 crossref_primary_10_1371_journal_pntd_0004421 crossref_primary_10_1534_g3_116_029546 crossref_primary_10_1186_s13071_017_2569_7 crossref_primary_10_1016_j_dcit_2025_100053 crossref_primary_10_1016_j_cois_2015_05_003 crossref_primary_10_1186_s12915_021_01158_2 crossref_primary_10_1016_j_cris_2025_100117 crossref_primary_10_1007_s10577_015_9480_x crossref_primary_10_1016_j_cois_2015_05_001 crossref_primary_10_1371_journal_pntd_0003456 crossref_primary_10_1371_journal_pntd_0006204 crossref_primary_10_1016_j_dci_2017_12_017 crossref_primary_10_1007_s13253_016_0249_2 crossref_primary_10_1186_s12866_018_1280_y crossref_primary_10_1186_s12864_023_09155_1 crossref_primary_10_1016_j_cois_2018_01_007 crossref_primary_10_1016_j_ygcen_2016_06_005 crossref_primary_10_1186_s12915_021_00975_9 crossref_primary_10_1093_gigascience_giaa020 crossref_primary_10_1371_journal_pone_0183858 crossref_primary_10_1002_arch_21587 crossref_primary_10_7717_peerj_10012 crossref_primary_10_1016_j_biotechadv_2016_02_009 crossref_primary_10_1016_j_meegid_2015_09_016 crossref_primary_10_1371_journal_pntd_0003448 crossref_primary_10_1016_j_ibmb_2015_11_010 crossref_primary_10_1038_srep20334 crossref_primary_10_1093_jme_tjac004 crossref_primary_10_3390_microorganisms12030568 crossref_primary_10_1128_AEM_00553_15 crossref_primary_10_1371_journal_pone_0207999 crossref_primary_10_1093_molbev_msw264 crossref_primary_10_1016_j_cell_2020_07_023 crossref_primary_10_1186_s12864_019_5665_6 crossref_primary_10_1371_journal_pntd_0004121 crossref_primary_10_1016_j_pt_2024_04_011 crossref_primary_10_3390_insects5040885 crossref_primary_10_1371_journal_pone_0273543 crossref_primary_10_1093_jee_toaf113 crossref_primary_10_1186_s12864_016_3187_z crossref_primary_10_1017_S0031182018000574 crossref_primary_10_1093_molbev_msx168 crossref_primary_10_1007_s13361_015_1248_1 crossref_primary_10_1007_s42690_020_00213_9 crossref_primary_10_1371_journal_pcbi_1006940 crossref_primary_10_1016_j_pt_2014_06_007 crossref_primary_10_1073_pnas_1516778112 crossref_primary_10_1371_journal_ppat_1005058 crossref_primary_10_1128_msphere_00685_20 crossref_primary_10_1371_journal_pntd_0005454 crossref_primary_10_1016_j_cois_2015_01_004 crossref_primary_10_3390_genes11091063 crossref_primary_10_1186_s12866_018_1281_x crossref_primary_10_1111_imb_12382 crossref_primary_10_1128_AEM_01150_14 crossref_primary_10_1002_jez_b_23220 crossref_primary_10_1016_j_pt_2014_08_006 crossref_primary_10_1186_s13059_016_1049_2 crossref_primary_10_1016_j_cois_2017_02_003 crossref_primary_10_3389_fmicb_2019_01650 crossref_primary_10_1186_s13100_015_0044_6 crossref_primary_10_1016_j_tig_2015_04_007 crossref_primary_10_1186_s12864_015_1921_6 |
| ContentType | Journal Article |
| Contributor | Wilson, Richard K Swain, Martin T Schoofs, Liliane Sanders, Mandy J Ooi, Cher-Pheng Hattori, Masahira Ravel, Sophie Zhang, Qirui Winzerling, Joy J Warren, Wesley Koekemoer, Jacobus J O Berriman, Matthew Attardo, Geoffrey M Baumann, Aaron A Obiero, George F O Falchetto, Marco Field, Linda M Toyoda, Atsushi Cotton, James A Lawson, Daniel Caers, Jelle Geiser, L Touré, Yeya Hughes, Daniel S T Meuti, Megan E Mireji, Paul O Lehane, Michael J Marco, Heather G Scolari, Francesca Aksoy, Serap Suzuki, Yutaka Price, David P Michalkova, Veronika Inoue, Noboru Larkin, Denis M Darby, Alistair C Hide, Winston Taylor, Todd D Ribeiro, José M C Srivastava, Tulika P Hertz-Fowler, Christiane Kibet, Caleb K Megy, Karyn Haines, Lee R Christoffels, Alan Sim, Cheolho Denlinger, David L Jonas, Mario Nyanjom, Steven R G Dashti, Zahra Jalali Sefid Telleria, Erich L Marucha, Kevin K Sharma, Vineet Bourtzis, Kostas Hu, Wanqi Macharia, Rosaline W Riehle, Michael A Peyton, Justin T Zhou, Jing-Jiang Gomulski, Ludvik M Fu, Shuhua Van Den Abbeele, Jan Benoit, Joshua B Rose, Clair P |
| Contributor_xml | – sequence: 1 givenname: Junichi surname: Watanabe fullname: Watanabe, Junichi – sequence: 2 givenname: Masahira surname: Hattori fullname: Hattori, Masahira – sequence: 3 givenname: Matthew surname: Berriman fullname: Berriman, Matthew – sequence: 4 givenname: Michael J surname: Lehane fullname: Lehane, Michael J – sequence: 5 givenname: Neil surname: Hall fullname: Hall, Neil – sequence: 6 givenname: Philippe surname: Solano fullname: Solano, Philippe – sequence: 7 givenname: Serap surname: Aksoy fullname: Aksoy, Serap – sequence: 8 givenname: Winston surname: Hide fullname: Hide, Winston – sequence: 9 givenname: Yeya surname: Touré fullname: Touré, Yeya – sequence: 10 givenname: Geoffrey M surname: Attardo fullname: Attardo, Geoffrey M – sequence: 11 givenname: Alistair C surname: Darby fullname: Darby, Alistair C – sequence: 12 givenname: Atsushi surname: Toyoda fullname: Toyoda, Atsushi – sequence: 13 givenname: Christiane surname: Hertz-Fowler fullname: Hertz-Fowler, Christiane – sequence: 14 givenname: Denis M surname: Larkin fullname: Larkin, Denis M – sequence: 15 givenname: James A surname: Cotton fullname: Cotton, James A – sequence: 16 givenname: Mandy J surname: Sanders fullname: Sanders, Mandy J – sequence: 17 givenname: Martin T surname: Swain fullname: Swain, Martin T – sequence: 18 givenname: Michael A surname: Quail fullname: Quail, Michael A – sequence: 19 givenname: Noboru surname: Inoue fullname: Inoue, Noboru – sequence: 20 givenname: Sophie surname: Ravel fullname: Ravel, Sophie – sequence: 21 givenname: Todd D surname: Taylor fullname: Taylor, Todd D – sequence: 22 givenname: Tulika P surname: Srivastava fullname: Srivastava, Tulika P – sequence: 23 givenname: Vineet surname: Sharma fullname: Sharma, Vineet – sequence: 24 givenname: Wesley surname: Warren fullname: Warren, Wesley – sequence: 25 givenname: Richard K surname: Wilson fullname: Wilson, Richard K – sequence: 26 givenname: Yutaka surname: Suzuki fullname: Suzuki, Yutaka – sequence: 27 givenname: Daniel surname: Lawson fullname: Lawson, Daniel – sequence: 28 givenname: Daniel S T surname: Hughes fullname: Hughes, Daniel S T – sequence: 29 givenname: Karyn surname: Megy fullname: Megy, Karyn – sequence: 30 givenname: Daniel K surname: Masiga fullname: Masiga, Daniel K – sequence: 31 givenname: Paul O surname: Mireji fullname: Mireji, Paul O – sequence: 32 givenname: Immo A surname: Hansen fullname: Hansen, Immo A – sequence: 33 givenname: Jan surname: Van Den Abbeele fullname: Van Den Abbeele, Jan – sequence: 34 givenname: Joshua B surname: Benoit fullname: Benoit, Joshua B – sequence: 35 givenname: Kostas surname: Bourtzis fullname: Bourtzis, Kostas – sequence: 36 givenname: George F O surname: Obiero fullname: Obiero, George F O – sequence: 37 givenname: Hugh M surname: Robertson fullname: Robertson, Hugh M – sequence: 38 givenname: Jeffery W surname: Jones fullname: Jones, Jeffery W – sequence: 39 givenname: Jing-Jiang surname: Zhou fullname: Zhou, Jing-Jiang – sequence: 40 givenname: Linda M surname: Field fullname: Field, Linda M – sequence: 41 givenname: Markus surname: Friedrich fullname: Friedrich, Markus – sequence: 42 givenname: Steven R G surname: Nyanjom fullname: Nyanjom, Steven R G – sequence: 43 givenname: Erich L surname: Telleria fullname: Telleria, Erich L – sequence: 44 givenname: Guy surname: Caljon fullname: Caljon, Guy – sequence: 45 givenname: José M C surname: Ribeiro fullname: Ribeiro, José M C – sequence: 46 givenname: Alvaro surname: Acosta-Serrano fullname: Acosta-Serrano, Alvaro – sequence: 47 givenname: Cher-Pheng surname: Ooi fullname: Ooi, Cher-Pheng – sequence: 48 givenname: Clair surname: Rose fullname: Rose, Clair – sequence: 49 givenname: David P surname: Price fullname: Price, David P – sequence: 50 givenname: Lee R surname: Haines fullname: Haines, Lee R – sequence: 51 givenname: Alan surname: Christoffels fullname: Christoffels, Alan – sequence: 52 givenname: Cheolho surname: Sim fullname: Sim, Cheolho – sequence: 53 givenname: Daphne Q D surname: Pham fullname: Pham, Daphne Q D – sequence: 54 givenname: David L surname: Denlinger fullname: Denlinger, David L – sequence: 55 givenname: L surname: Geiser fullname: Geiser, L – sequence: 56 givenname: Irene A surname: Omedo fullname: Omedo, Irene A – sequence: 57 givenname: Joy J surname: Winzerling fullname: Winzerling, Joy J – sequence: 58 givenname: Justin T surname: Peyton fullname: Peyton, Justin T – sequence: 59 givenname: Kevin K surname: Marucha fullname: Marucha, Kevin K – sequence: 60 givenname: Mario surname: Jonas fullname: Jonas, Mario – sequence: 61 givenname: Megan E surname: Meuti fullname: Meuti, Megan E – sequence: 62 givenname: Neil D surname: Rawlings fullname: Rawlings, Neil D – sequence: 63 givenname: Qirui surname: Zhang fullname: Zhang, Qirui – sequence: 64 givenname: Rosaline W surname: Macharia fullname: Macharia, Rosaline W – sequence: 65 givenname: Veronika surname: Michalkova fullname: Michalkova, Veronika – sequence: 66 givenname: Zahra Jalali Sefid surname: Dashti fullname: Dashti, Zahra Jalali Sefid – sequence: 67 givenname: Aaron A surname: Baumann fullname: Baumann, Aaron A – sequence: 68 givenname: Gerd surname: Gäde fullname: Gäde, Gerd – sequence: 69 givenname: Heather G surname: Marco fullname: Marco, Heather G – sequence: 70 givenname: Jelle surname: Caers fullname: Caers, Jelle – sequence: 71 givenname: Liliane surname: Schoofs fullname: Schoofs, Liliane – sequence: 72 givenname: Michael A surname: Riehle fullname: Riehle, Michael A – sequence: 73 givenname: Wanqi surname: Hu fullname: Hu, Wanqi – sequence: 74 givenname: Zhijian surname: Tu fullname: Tu, Zhijian – sequence: 75 givenname: Aaron M surname: Tarone fullname: Tarone, Aaron M – sequence: 76 givenname: Anna R surname: Malacrida fullname: Malacrida, Anna R – sequence: 77 givenname: Caleb K surname: Kibet fullname: Kibet, Caleb K – sequence: 78 givenname: Francesca surname: Scolari fullname: Scolari, Francesca – sequence: 79 givenname: Jacobus J O surname: Koekemoer fullname: Koekemoer, Jacobus J O – sequence: 80 givenname: Judith surname: Willis fullname: Willis, Judith – sequence: 81 givenname: Ludvik M surname: Gomulski fullname: Gomulski, Ludvik M – sequence: 82 givenname: Marco surname: Falchetto fullname: Falchetto, Marco – sequence: 83 givenname: Maxwell J surname: Scott fullname: Scott, Maxwell J – sequence: 84 givenname: Shuhua surname: Fu fullname: Fu, Shuhua |
| CorporateAuthor | International Glossina Genome Initiative |
| CorporateAuthor_xml | – name: International Glossina Genome Initiative |
| DBID | CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1126/science.1249656 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Sciences (General) Biology |
| EISSN | 1095-9203 |
| ExternalDocumentID | 24763584 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GrantInformation_xml | – fundername: FIC NIH HHS grantid: R03 TW009444 – fundername: NIAID NIH HHS grantid: R01 AI081774 – fundername: NHGRI NIH HHS grantid: U54 HG003079 – fundername: Wellcome Trust – fundername: FIC NIH HHS grantid: R03 TW008413 – fundername: Medical Research Council grantid: MR/K002279/1 – fundername: Wellcome Trust grantid: 098051 – fundername: NIAID NIH HHS grantid: R01 AI051584 – fundername: NCI NIH HHS grantid: F32 CA091768 – fundername: FIC NIH HHS grantid: D43 TW007391 |
| GroupedDBID | --- --Z -DZ -ET -~X .-4 ..I .55 .DC .HR 08G 0R~ 0WA 123 18M 2FS 2KS 2WC 2XV 34G 36B 39C 3R3 4.4 4R4 53G 5RE 66. 6OB 6TJ 7X2 7~K 85S 8F7 AABCJ AACGO AAIKC AAJYS AAMNW AANCE AAWTO AAYJJ ABBHK ABCQX ABDBF ABDEX ABDQB ABEFU ABIVO ABJNI ABOCM ABPLY ABPMR ABPPZ ABQIJ ABTLG ABWJO ABXSQ ABZEH ACBEA ACBEC ACGFO ACGFS ACGOD ACHIC ACIWK ACMJI ACNCT ACPRK ACQOY ACUHS ADDRP ADMHC ADQXQ ADUKH ADULT ADXHL AEGBM AENEX AETEA AEUPB AEXZC AFBNE AFCHL AFFDN AFFNX AFHKK AFQFN AFRAH AGNAY AGSOS AHMBA AIDAL AIDUJ AJGZS ALIPV ALMA_UNASSIGNED_HOLDINGS ALSLI AQVQM ASPBG AVWKF BKF BLC C45 C51 CGR CS3 CUY CVF DB2 DCCCD DU5 EBS ECM EIF EJD EMOBN F5P FA8 FEDTE HZ~ I.T IAO IEA IGS IH2 IHR INH INR IOF IOV IPO IPSME IPY ISE J9C JAAYA JBMMH JCF JENOY JHFFW JKQEH JLS JLXEF JPM JSG JST K-O KCC L7B LSO LU7 M0P MQT MVM N9A NEJ NHB NPM O9- OCB OFXIZ OGEVE OMK OVD P-O P2P PQQKQ PZZ QJJ RHI RXW SA0 SC5 SJN TAE TEORI TN5 TWZ UBW UCV UHB UKR UMD UNMZH UQL USG VVN WH7 WI4 X7M XJF XZL Y6R YK4 YKV YNT YOJ YR2 YR5 YRY YSQ YV5 YWH YYP YYQ YZZ ZCA ZE2 ~02 ~KM ~ZZ 7X8 |
| ID | FETCH-LOGICAL-c547t-f238e7bb75cc2435d6a3a1e16e10b69650d120d5a7875dd9e00e9e58a35afa2f2 |
| IEDL.DBID | 7X8 |
| ISICitedReferencesCount | 197 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000334867800033&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1095-9203 |
| IngestDate | Thu Oct 02 11:17:05 EDT 2025 Mon Jul 21 06:05:47 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6182 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c547t-f238e7bb75cc2435d6a3a1e16e10b69650d120d5a7875dd9e00e9e58a35afa2f2 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://pure.aber.ac.uk/portal/en/publications/genome-sequence-of-the-tsetse-fly-glossina-morsitans(a014c008-1e2e-4d6c-808b-c69fa8c3d667).html |
| PMID | 24763584 |
| PQID | 1519263828 |
| PQPubID | 23479 |
| ParticipantIDs | proquest_miscellaneous_1519263828 pubmed_primary_24763584 |
| PublicationCentury | 2000 |
| PublicationDate | 2014-04-25 |
| PublicationDateYYYYMMDD | 2014-04-25 |
| PublicationDate_xml | – month: 04 year: 2014 text: 2014-04-25 day: 25 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Science (American Association for the Advancement of Science) |
| PublicationTitleAlternate | Science |
| PublicationYear | 2014 |
| References | 24763563 - Science. 2014 Apr 25;344(6182):349-50. doi: 10.1126/science.344.6182.349. |
| References_xml | – reference: 24763563 - Science. 2014 Apr 25;344(6182):349-50. doi: 10.1126/science.344.6182.349. |
| SSID | ssj0009593 |
| Score | 2.5498044 |
| Snippet | Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and... |
| SourceID | proquest pubmed |
| SourceType | Aggregation Database Index Database |
| StartPage | 380 |
| SubjectTerms | Animals Blood Feeding Behavior Female Genes, Insect Genome, Insect Insect Proteins - genetics Insect Proteins - physiology Insect Vectors - genetics Insect Vectors - microbiology Insect Vectors - parasitology Insect Vectors - physiology Microbiota Molecular Sequence Annotation Molecular Sequence Data Reproduction - genetics Salivary Glands - parasitology Salivary Glands - physiology Sensation - genetics Sequence Analysis, DNA Symbiosis Trypanosoma - physiology Trypanosomiasis, African - transmission Tsetse Flies - genetics Tsetse Flies - microbiology Tsetse Flies - parasitology Tsetse Flies - physiology Wolbachia - genetics Wolbachia - physiology |
| Title | Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/24763584 https://www.proquest.com/docview/1519263828 |
| Volume | 344 |
| WOSCitedRecordID | wos000334867800033&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LS8QwEA7qKnjx_VhfRPCgh2qaJk3rRURcPOjiQWE9lTxhYbdVWxf23ztpuyiCIAgl9JBCmM7jy2QyH0InTLg0trDJSWikA8aFCpQiaaBZqKTgKYlNfVH4XvT7yWCQPrYJt7Itq5z5xNpRm0L7HPkFRKaUgrLQ5Or1LfCsUf50taXQmEedCKCM12oxSH423Q2J5yOkJGpb-3y7NHPuuZdjHv-OL-s401v97wrX0EqLMPF1oxLraM7mG2ip4ZycbqD11ppLfNq2nD7bRC_wWowtnhVW48JhQIa4Ki082I2mMHsE8XSYSzwufCEHhLizSzypk_5-ekM4lOPqfQoOpiiL8VCWw3ILPfdun27ugpZ0IdCciSpwEMOtUEpwrSlgKRPLSIY2jG1IVAyyIiakxHAJls6NSS0hNrU8kRGXTlJHt9FCXuR2F2HrEu0MM5arFPZFQmkWKeYhp2RUk6SLjmeCzECp_UmFzG3xUWZfouyineZvZK9N942MMt9DL2F7f_h6Hy0DwKkrbSg_QB0HJm0P0aKeVMPy_ajWFhj7jw-fyQjKjw |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Genome+sequence+of+the+tsetse+fly+%28Glossina+morsitans%29%3A+vector+of+African+trypanosomiasis&rft.jtitle=Science+%28American+Association+for+the+Advancement+of+Science%29&rft.date=2014-04-25&rft.eissn=1095-9203&rft.volume=344&rft.issue=6182&rft.spage=380&rft_id=info:doi/10.1126%2Fscience.1249656&rft_id=info%3Apmid%2F24763584&rft_id=info%3Apmid%2F24763584&rft.externalDocID=24763584 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1095-9203&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1095-9203&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1095-9203&client=summon |