Purifying stem cell‐derived red blood cells: a high‐throughput label‐free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration

Cell‐based therapeutics, such as in vitro manufactured red blood cells (mRBCs), are different to traditional biopharmaceutical products (the final product being the cells themselves as opposed to biological molecules such as proteins) and that presents a challenge of developing new robust and econom...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Biotechnology and bioengineering Ročník 117; číslo 7; s. 2032 - 2045
Hlavní autori:	Guzniczak, Ewa, Otto, Oliver, Whyte, Graeme, Chandra, Tamir, Robertson, Neil A., Willoughby, Nik, Jimenez, Melanie, Bridle, Helen
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Wiley Subscription Services, Inc 01.07.2020 John Wiley and Sons Inc
Predmet:	Biopharmaceuticals CD34 antigen Cell Line Cell Separation - instrumentation Cord blood Deformability Equipment Design Erythrocytes Erythrocytes - cytology Erythropoiesis Filtration Filtration - instrumentation Fluorescence Formability Gene expression Humans Manufacturing industry Mechanical properties Membrane filtration Membranes Microfluidic Analytical Techniques - instrumentation Microfluidics Nuclei (cytology) Purification Purity Separation sorting spiral microchannel Stem cells Stem Cells - cytology stem cell‐derived red blood cells Umbilical cord deformability stem cell-derived red blood cells purification sorting spiral microchannel
ISSN:	0006-3592, 1097-0290, 1097-0290
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!