Predicting breast cancer response to neoadjuvant chemotherapy using pretreatment diffuse optical spectroscopic texture analysis

Background: Diffuse optical spectroscopy (DOS) has been demonstrated capable of monitoring response to neoadjuvant chemotherapy (NAC) in locally advanced breast cancer (LABC) patients. In this study, we evaluate texture features of pretreatment DOS functional maps for predicting LABC response to NAC...

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Veröffentlicht in:	British journal of cancer Jg. 116; H. 10; S. 1329 - 1339
Hauptverfasser:	Tran, William T, Gangeh, Mehrdad J, Sannachi, Lakshmanan, Chin, Lee, Watkins, Elyse, Bruni, Silvio G, Rastegar, Rashin Fallah, Curpen, Belinda, Trudeau, Maureen, Gandhi, Sonal, Yaffe, Martin, Slodkowska, Elzbieta, Childs, Charmaine, Sadeghi-Naini, Ali, Czarnota, Gregory J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 09.05.2017 Nature Publishing Group
Schlagworte:	631/1647/527 692/53/2423 692/699/67/1059/99 692/699/67/1347 Accuracy Anthracyclines - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Area Under Curve Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - diagnostic imaging Breast Neoplasms - drug therapy Breast Neoplasms - pathology Bridged-Ring Compounds - administration & dosage Cancer Research Cancer therapies Carcinoma, Ductal, Breast - diagnostic imaging Carcinoma, Ductal, Breast - drug therapy Carcinoma, Ductal, Breast - pathology Carcinoma, Lobular - drug therapy Carcinoma, Lobular - pathology Chemotherapy Chemotherapy, Adjuvant Drug Resistance Epidemiology Female Health sciences Hemoglobin Hemoglobins - metabolism Humans Magnetic resonance imaging Mammography Medical imaging Medical research Middle Aged Molecular Medicine Neoadjuvant Therapy Oncology Oxygen - metabolism Predictive Value of Tests Radiation ROC Curve Spectrum Analysis Taxoids - administration & dosage Tomography, Optical - methods Translational Therapeutics Trastuzumab - administration & dosage Tumor Burden Tumors United Kingdom > UK Toronto Ontario Canada Canada imaging biomarkers diffuse optical spectroscopy imaging breast cancer
ISSN:	0007-0920, 1532-1827, 1532-1827
Online-Zugang:	Volltext
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