Coronary Calcium Score and Cardiovascular Risk

Coronary artery calcium (CAC) is a highly specific feature of coronary atherosclerosis. On the basis of single-center and multicenter clinical and population-based studies with short-term and long-term outcomes data (up to 15-year follow-up), CAC scoring has emerged as a widely available, consistent...

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Veröffentlicht in:Journal of the American College of Cardiology Jg. 72; H. 4; S. 434
Hauptverfasser: Greenland, Philip, Blaha, Michael J, Budoff, Matthew J, Erbel, Raimund, Watson, Karol E
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 24.07.2018
Schlagworte:
Cardiovascular Diseases - diagnosis
Cardiovascular Diseases - pathology
Cardiovascular Diseases - prevention & control
Coronary Vessels - pathology
Disease Management
Disease Progression
Humans
Risk Assessment
Vascular Calcification - diagnosis
Vascular Calcification - prevention & control
aspirin
coronary heart disease
atherosclerotic cardiovascular disease
coronary artery calcification
statins
ISSN:1558-3597, 1558-3597
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Zusammenfassung:Coronary artery calcium (CAC) is a highly specific feature of coronary atherosclerosis. On the basis of single-center and multicenter clinical and population-based studies with short-term and long-term outcomes data (up to 15-year follow-up), CAC scoring has emerged as a widely available, consistent, and reproducible means of assessing risk for major cardiovascular outcomes, especially useful in asymptomatic people for planning primary prevention interventions such as statins and aspirin. CAC testing in asymptomatic populations is cost effective across a broad range of baseline risk. This review summarizes evidence concerning CAC, including its pathobiology, modalities for detection, predictive role, use in prediction scoring algorithms, CAC progression, evidence that CAC changes the clinical approach to the patient and patient behavior, novel applications of CAC, future directions in scoring CAC scans, and new CAC guidelines.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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ISSN:1558-3597
1558-3597
DOI:10.1016/j.jacc.2018.05.027