ClustalW-MPI: ClustalW analysis using distributed and parallel computing

ClustalW is a tool for aligning multiple protein or nucleotide sequences. The alignment is achieved via three steps: pairwise alignment, guide-tree generation and progressive alignment. ClustalW-MPI is a distributed and parallel implementation of ClustalW. All three steps have been parallelized to r...

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Bibliographic Details
Published in:Bioinformatics Vol. 19; no. 12; pp. 1585 - 1586
Main Author: Li, Kuo-Bin
Format: Journal Article
Language:English
Published: Oxford Oxford University Press 12.08.2003
Oxford Publishing Limited (England)
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ISSN:1367-4803, 1460-2059, 1367-4811
Online Access:Get full text
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Summary:ClustalW is a tool for aligning multiple protein or nucleotide sequences. The alignment is achieved via three steps: pairwise alignment, guide-tree generation and progressive alignment. ClustalW-MPI is a distributed and parallel implementation of ClustalW. All three steps have been parallelized to reduce the execution time. The software uses a message-passing library called MPI (Message Passing Interface) and runs on distributed workstation clusters as well as on traditional parallel computers. Availability:The source codes are written in ISO C and are available at http://www.bii.a-star.edu.sg/software/clustalw-mpi/. An open source implementations of MPI http://www-unix.mcs.anl.gov/mpi/. Contact: kuobin@bii.a-star.edu.sg
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PII:1460-2059
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ISSN:1367-4803
1460-2059
1367-4811
DOI:10.1093/bioinformatics/btg192