Nanosensors in the detection of antihypertension drugs, a golden step for medication adherence monitoring

Hypertension is associated with structural and functional changes in blood vessels with increased arteriosclerosis, vascular inflammation, and endothelial dysfunction. Decreased adherence (compliance) to antihypertensive medications contributes significantly to morbidity and mortality in hypertensiv...

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Published in:Heliyon Vol. 9; no. 9; p. e19467
Main Authors: Mobed, Ahmad, Gholami, Sarah, Tahavvori, Amir, Ghazi, Farhood, Masoumi, Zahra, Alipourfard, Iraj, Naderian, Ramtin, Mohammadzadeh, Mehran
Format: Journal Article
Language:English
Published: Elsevier Ltd 01.09.2023
Elsevier
Subjects:
Antihypertension drugs (AHTDs)
biomarkers
biosensors
blood
Clinical chemistry
Hypertension
inflammation
lifestyle
Medication adherence
mortality
Nanosensors
Review
Hypertension
Medication adherence
Antihypertension drugs (AHTDs)
Nanosensors
Clinical chemistry
ISSN:2405-8440, 2405-8440
Online Access:Get full text
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Summary:Hypertension is associated with structural and functional changes in blood vessels with increased arteriosclerosis, vascular inflammation, and endothelial dysfunction. Decreased adherence (compliance) to antihypertensive medications contributes significantly to morbidity and mortality in hypertensive patients. Antihypertensive drugs (AHTDs) and lifestyle changes are the main cornerstones for treating hypertension. Several approaches have been described in the literature for determining AHTDs based on different analytical techniques. Amongst biosensors are one of the most attractive tools due to their inherent advantages. Biosensors are used for the detection of wide range of biomarkers as well as different drugs in past two decades. The main focus of the present study is to review the latest biosensors developed for the detection of AHTDs. Readers of the present study will be able to familiarize themselves with biosensors as advanced and modern diagnostic tools while reviewing the most widely used AHTDs. In the present study, the routine methods are first reviewed and while examining their advantages and disadvantages, biosensors have been introduced as ideal alternative tools. [Display omitted]
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Co-first authors (Equal contribution).
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2023.e19467