Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

Elevated lipoprotein(a) [Lp(a)] is a prevalent, independent cardiovascular risk factor, but the underlying mechanisms responsible for its pathogenicity are poorly defined. Because Lp(a) is the prominent carrier of proinflammatory oxidized phospholipids (OxPLs), part of its atherothrombosis might be...

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Vydané v:	Circulation (New York, N.Y.) Ročník 134; číslo 8; s. 611
Hlavní autori:	van der Valk, Fleur M, Bekkering, Siroon, Kroon, Jeffrey, Yeang, Calvin, Van den Bossche, Jan, van Buul, Jaap D, Ravandi, Amir, Nederveen, Aart J, Verberne, Hein J, Scipione, Corey, Nieuwdorp, Max, Joosten, Leo A B, Netea, Mihai G, Koschinsky, Marlys L, Witztum, Joseph L, Tsimikas, Sotirios, Riksen, Niels P, Stroes, Erik S G
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 23.08.2016
Predmet:	Adult Aged Aorta - diagnostic imaging Aorta - metabolism Cell Movement - physiology Cells, Cultured Female Humans Inflammation - diagnostic imaging Inflammation - metabolism Inflammation Mediators - metabolism Leukocytes, Mononuclear - metabolism Lipoprotein(a) - metabolism Male Middle Aged Phospholipids - metabolism Positron Emission Tomography Computed Tomography atherosclerosis monocytes lipoproteins
ISSN:	1524-4539, 1524-4539
On-line prístup:	Zistit podrobnosti o prístupe
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