Amyloid imaging in mild cognitive impairment subtypes

Objective We utilized the amyloid imaging ligand Pittsburgh Compound B (PiB) to determine the presence of Alzheimer's disease (AD) pathology in different mild cognitive impairment (MCI) subtypes and to relate increased PiB binding to other markers of early AD and longitudinal outcome. Methods T...

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Veröffentlicht in:	Annals of neurology Jg. 65; H. 5; S. 557 - 568
Hauptverfasser:	Wolk, David A., Price, Julie C., Saxton, Judy A., Snitz, Beth E., James, Jeffrey A., Lopez, Oscar L., Aizenstein, Howard J., Cohen, Ann D., Weissfeld, Lisa A., Mathis, Chester A., Klunk, William E., DeKosky, Steven T.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.05.2009 Wiley-Liss
Schlagworte:	Aged Aged, 80 and over Amyloid - metabolism Aniline Compounds Biological and medical sciences Brain Mapping Cognition Disorders - classification Cognition Disorders - diagnostic imaging Cognition Disorders - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Follow-Up Studies Hippocampus - diagnostic imaging Hippocampus - pathology Humans Magnetic Resonance Imaging - methods Male Medical sciences Middle Aged Neurology Neuropsychological Tests Positron-Emission Tomography - methods Psychometrics - methods Thiazoles Nervous system diseases Amyloid mild cognitive impairment Cognitive disorder Subtype
ISSN:	0364-5134, 1531-8249, 1531-8249
Online-Zugang:	Volltext
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