Exploring genomic alteration in pediatric cancer using ProteinPaint

The pediatric data set consists of 27,188 validated somatic coding lesions acquired at diagnosis or relapse from 17 subtypes of pediatric cancer, 252 pathogenic or loss-of-function germline lesions detected in >1,000 pediatric patients with cancer of 21 subtypes6 and RNA sequencing (RNA-seq) data...

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Bibliographic Details
Published in:	Nature genetics Vol. 48; no. 1; pp. 4 - 6
Main Authors:	Zhou, Xin, Edmonson, Michael N, Wilkinson, Mark R, Patel, Aman, Wu, Gang, Liu, Yu, Li, Yongjin, Zhang, Zhaojie, Rusch, Michael C, Parker, Matthew, Becksfort, Jared, Downing, James R, Zhang, Jinghui
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.01.2016 Nature Publishing Group
Subjects:	45 45/23 631/114/794 692/699/67 Agriculture Animal Genetics and Genomics Biomedicine Cancer Cancer Research Cancer treatment Child Children & youth correspondence Databases, Genetic Gene expression Gene Expression Regulation, Neoplastic Gene Function Genome, Human Genomes Human Genetics Humans Kinases Lesions Medical research Mutation Neoplasms - genetics Pediatrics Proteins Proteins - genetics Software Studies Tumors User-Computer Interface Visualization
ISSN:	1061-4036, 1546-1718, 1546-1718
Online Access:	Get full text
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