Targeting of Low-Dose CT Screening According to the Risk of Lung-Cancer Death

The 60% of patients at highest risk for lung cancer in the National Lung Screening Trial accounted for 88% of the lung-cancer deaths prevented by low-dose CT screening. The use of risk assessment can improve the yield from low-dose CT screening for lung cancer. Lung cancer is the most common cause o...

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Veröffentlicht in:	The New England journal of medicine Jg. 369; H. 3; S. 245 - 254
Hauptverfasser:	Kovalchik, Stephanie A, Tammemagi, Martin, Berg, Christine D, Caporaso, Neil E, Riley, Tom L, Korch, Mary, Silvestri, Gerard A, Chaturvedi, Anil K, Katki, Hormuzd A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Waltham, MA Massachusetts Medical Society 18.07.2013
Schlagworte:	Aged Biological and medical sciences Computed tomography Death False Positive Reactions Female General aspects Humans Lung - diagnostic imaging Lung cancer Lung Neoplasms - diagnostic imaging Lung Neoplasms - mortality Lung Neoplasms - prevention & control Male Mass Screening Medical sciences Medical screening Middle Aged Pneumology Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Radiation Dosage Radiography Risk Risk assessment Smoking Tomography, X-Ray Computed Tumors of the respiratory system and mediastinum United States > US Lung disease Radiodiagnosis Targeting Respiratory disease Lung cancer Low dose Mortality Risk Malignant tumor Medical screening Medicine Risk factor Medical imagery Bronchus disease Death Computerized axial tomography Cancer
ISSN:	0028-4793, 1533-4406, 1533-4406
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Zusammenfassung:	The 60% of patients at highest risk for lung cancer in the National Lung Screening Trial accounted for 88% of the lung-cancer deaths prevented by low-dose CT screening. The use of risk assessment can improve the yield from low-dose CT screening for lung cancer. Lung cancer is the most common cause of cancer-related death in the United States, accounting for 28% and 26% of all cancer deaths among men and women, respectively. 1 Recent results from the National Lung Screening Trial (NLST), which showed a 20% reduction in lung-cancer mortality with low-dose computed tomography (CT) screening, as compared with chest radiography, highlighted the opportunity to reduce the burden of death from lung cancer. 2 With 94 million current and former smokers in the United States, 3 deciding which smokers to target for low-dose CT screening remains an important public health challenge, given the potential costs and harms . . .
Bibliographie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Undefined-3
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa1301851