Targeting of Low-Dose CT Screening According to the Risk of Lung-Cancer Death

The 60% of patients at highest risk for lung cancer in the National Lung Screening Trial accounted for 88% of the lung-cancer deaths prevented by low-dose CT screening. The use of risk assessment can improve the yield from low-dose CT screening for lung cancer. Lung cancer is the most common cause o...

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Vydáno v:The New England journal of medicine Ročník 369; číslo 3; s. 245 - 254
Hlavní autoři: Kovalchik, Stephanie A, Tammemagi, Martin, Berg, Christine D, Caporaso, Neil E, Riley, Tom L, Korch, Mary, Silvestri, Gerard A, Chaturvedi, Anil K, Katki, Hormuzd A
Médium: Journal Article
Jazyk:angličtina
Vydáno: Waltham, MA Massachusetts Medical Society 18.07.2013
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ISSN:0028-4793, 1533-4406, 1533-4406
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Shrnutí:The 60% of patients at highest risk for lung cancer in the National Lung Screening Trial accounted for 88% of the lung-cancer deaths prevented by low-dose CT screening. The use of risk assessment can improve the yield from low-dose CT screening for lung cancer. Lung cancer is the most common cause of cancer-related death in the United States, accounting for 28% and 26% of all cancer deaths among men and women, respectively. 1 Recent results from the National Lung Screening Trial (NLST), which showed a 20% reduction in lung-cancer mortality with low-dose computed tomography (CT) screening, as compared with chest radiography, highlighted the opportunity to reduce the burden of death from lung cancer. 2 With 94 million current and former smokers in the United States, 3 deciding which smokers to target for low-dose CT screening remains an important public health challenge, given the potential costs and harms . . .
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa1301851