Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway

Low plasma B-vitamin levels and elevated homocysteine have been associated with cancer, cardiovascular disease and neurodegenerative disorders. Common variants in FUT2 on chromosome 19q13 were associated with plasma vitamin B12 levels among women in a genome-wide association study in the Nurses'...

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Vydané v:	Human molecular genetics Ročník 18; číslo 23; s. 4677
Hlavní autori:	Hazra, Aditi, Kraft, Peter, Lazarus, Ross, Chen, Constance, Chanock, Stephen J, Jacques, Paul, Selhub, Jacob, Hunter, David J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.12.2009
Predmet:	Adult Chromosomes, Human - genetics DNA-Binding Proteins - blood Female Folic Acid - blood Genome-Wide Association Study Homocysteine - blood Humans Male Methylenetetrahydrofolate Reductase (NADPH2) - genetics Middle Aged Polymorphism, Single Nucleotide Transcription Factors - blood Vitamin B 12 - blood
ISSN:	1460-2083, 1460-2083
On-line prístup:	Zistit podrobnosti o prístupe
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