Molecular and cellular determinants of L-Dopa-induced dyskinesia in Parkinson’s Disease

Treatment with L-3,4-dihydroxyphenylalanine (L-Dopa) compensates for decreased striatal dopamine (DA) levels and reduces Parkinson’s disease (PD) symptoms. However, during disease progression, L-Dopa-induced dyskinesia (LID) develops virtually in all PD patients, making the control of PD symptoms di...

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Veröffentlicht in:	NPJ Parkinson's Disease Jg. 10; H. 1; S. 228 - 13
Hauptverfasser:	Servillo, Federica, De Carluccio, Maria, Di Lazzaro, Giulia, Campanelli, Federica, Marino, Gioia, Natale, Giuseppina, Ledonne, Ada, Massaro Cenere, Mariangela, Paldino, Emanuela, Di Giuda, Daniela, Picca, Anna, Bove, Francesco, Di Iorio, Riccardo, Angeloni, Benedetta, Cimmino, Angelo Tiziano, Bellomo, Giovanni, Picconi, Barbara, Bentivoglio, Anna Rita, Mercuri, Nicola Biagio, Parnetti, Lucilla, Ghiglieri, Veronica, Viscomi, Maria Teresa, Calabresi, Paolo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 30.11.2024 Nature Publishing Group Nature Portfolio
Schlagworte:	631/378/2591 692/617/375/1718 Animals Biomedical and Life Sciences Biomedicine Denervation Dopamine Dyskinesia Genotype & phenotype Health risk assessment Neurology Neurosciences Physiology Risk factors
ISSN:	2373-8057, 2373-8057
Online-Zugang:	Volltext
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