Giant mitochondria in cardiomyocytes: cellular architecture in health and disease

Giant mitochondria are frequently observed in different disease models within the brain, kidney, and liver. In cardiac muscle, these enlarged organelles are present across diverse physiological and pathophysiological conditions including in ageing and exercise, and clinically in alcohol-induced hear...

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Bibliographic Details
Published in:	Basic research in cardiology Vol. 118; no. 1; p. 39
Main Authors:	Li, Amy, Shami, Gerald J., Griffiths, Lisa, Lal, Sean, Irving, Helen, Braet, Filip
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 29.09.2023 Springer Nature B.V
Subjects:	Cardiac muscle Cardiology Cardiomyocytes Cardiomyopathies Coronary artery disease Disease Heart diseases Human tissues Humans Medicine Medicine & Public Health Mitochondria Mitochondria - metabolism Mitochondria, Heart - metabolism Mitochondrial Swelling Muscles Myocardium - metabolism Myocytes, Cardiac - metabolism Organelles Review Histopathological marker Muscle disease Cardiomyopathy Mitochondrion pathophysiology Giant and megamitochondria Mitochondrial aberrations
ISSN:	1435-1803, 0300-8428, 1435-1803
Online Access:	Get full text
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