Latent generative landscapes as maps of functional diversity in protein sequence space

Variational autoencoders are unsupervised learning models with generative capabilities, when applied to protein data, they classify sequences by phylogeny and generate de novo sequences which preserve statistical properties of protein composition. While previous studies focus on clustering and gener...

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Bibliographic Details
Published in:Nature communications Vol. 14; no. 1; pp. 2222 - 15
Main Authors: Ziegler, Cheyenne, Martin, Jonathan, Sinner, Claude, Morcos, Faruck
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 19.04.2023
Nature Publishing Group
Nature Portfolio
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ISSN:2041-1723, 2041-1723
Online Access:Get full text
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