M2b macrophage polarization and its roles in diseases
Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2)....
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| Published in: | Journal of leukocyte biology Vol. 106; no. 2; pp. 345 - 358 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
Oxford University Press
01.08.2019
John Wiley and Sons Inc |
| Subjects: | |
| ISSN: | 0741-5400, 1938-3673, 1938-3673 |
| Online Access: | Get full text |
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| Abstract | Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2). M2b, a subtype of M2 macrophages, has attracted increasing attention over the past decade due to its strong immune‐regulated and anti‐inflammatory effects. A wide variety of stimuli and multiple factors modulate M2b macrophage polarization in vitro and in vivo. M2b macrophages possess both protective and pathogenic roles in various diseases. Understanding the mechanisms of M2b macrophage activation and the modulation of their polarization might provide a great perspective for the design of novel therapeutic strategies. The purpose of this review is to discuss current knowledge of M2b macrophage polarization, the roles of M2b macrophages in a variety of diseases and the stimuli to modulate M2b macrophage polarization.
Review outlines the current knowledge of the stimuli of M2b macrophage polarization and the roles of these cells in diseases. |
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| AbstractList | Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2). M2b, a subtype of M2 macrophages, has attracted increasing attention over the past decade due to its strong immune‐regulated and anti‐inflammatory effects. A wide variety of stimuli and multiple factors modulate M2b macrophage polarization in vitro and in vivo. M2b macrophages possess both protective and pathogenic roles in various diseases. Understanding the mechanisms of M2b macrophage activation and the modulation of their polarization might provide a great perspective for the design of novel therapeutic strategies. The purpose of this review is to discuss current knowledge of M2b macrophage polarization, the roles of M2b macrophages in a variety of diseases and the stimuli to modulate M2b macrophage polarization.
Review outlines the current knowledge of the stimuli of M2b macrophage polarization and the roles of these cells in diseases. Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2). M2b, a subtype of M2 macrophages, has attracted increasing attention over the past decade due to its strong immune‐regulated and anti‐inflammatory effects. A wide variety of stimuli and multiple factors modulate M2b macrophage polarization in vitro and in vivo. M2b macrophages possess both protective and pathogenic roles in various diseases. Understanding the mechanisms of M2b macrophage activation and the modulation of their polarization might provide a great perspective for the design of novel therapeutic strategies. The purpose of this review is to discuss current knowledge of M2b macrophage polarization, the roles of M2b macrophages in a variety of diseases and the stimuli to modulate M2b macrophage polarization. Review outlines the current knowledge of the stimuli of M2b macrophage polarization and the roles of these cells in diseases. Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2). M2b, a subtype of M2 macrophages, has attracted increasing attention over the past decade due to its strong immune-regulated and anti-inflammatory effects. A wide variety of stimuli and multiple factors modulate M2b macrophage polarization in vitro and in vivo. M2b macrophages possess both protective and pathogenic roles in various diseases. Understanding the mechanisms of M2b macrophage activation and the modulation of their polarization might provide a great perspective for the design of novel therapeutic strategies. The purpose of this review is to discuss current knowledge of M2b macrophage polarization, the roles of M2b macrophages in a variety of diseases and the stimuli to modulate M2b macrophage polarization.Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2). M2b, a subtype of M2 macrophages, has attracted increasing attention over the past decade due to its strong immune-regulated and anti-inflammatory effects. A wide variety of stimuli and multiple factors modulate M2b macrophage polarization in vitro and in vivo. M2b macrophages possess both protective and pathogenic roles in various diseases. Understanding the mechanisms of M2b macrophage activation and the modulation of their polarization might provide a great perspective for the design of novel therapeutic strategies. The purpose of this review is to discuss current knowledge of M2b macrophage polarization, the roles of M2b macrophages in a variety of diseases and the stimuli to modulate M2b macrophage polarization. Macrophages play an important role in a wide variety of physiologic and pathologic processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages commonly exist in two distinct subsets: classically activated macrophages (M1) and alternatively activated macrophages (M2). M2b, a subtype of M2 macrophages, has attracted increasing attention over the past decade due to its strong immune-regulated and anti-inflammatory effects. A wide variety of stimuli and multiple factors modulate M2b macrophage polarization in vitro and in vivo. M2b macrophages possess both protective and pathogenic roles in various diseases. Understanding the mechanisms of M2b macrophage activation and the modulation of their polarization might provide a great perspective for the design of novel therapeutic strategies. The purpose of this review is to discuss current knowledge of M2b macrophage polarization, the roles of M2b macrophages in a variety of diseases and the stimuli to modulate M2b macrophage polarization. |
| Author | Guo, Jiao Zhang, Sheng‐xi Rong, Xiang‐lu Wang, Le‐xun Wu, Hui‐juan |
| AuthorAffiliation | 1 Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine Joint Laboratory of Guangdong Hong Kong and Macao on Glycolipid Metabolic Diseases Guangdong Key Laboratory of Metabolic Disease Prevention and Treatment of Traditional Chinese Medicine Institute of Chinese Medicine Sciences Guangdong Pharmaceutical University Guangzhou China |
| AuthorAffiliation_xml | – name: 1 Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine Joint Laboratory of Guangdong Hong Kong and Macao on Glycolipid Metabolic Diseases Guangdong Key Laboratory of Metabolic Disease Prevention and Treatment of Traditional Chinese Medicine Institute of Chinese Medicine Sciences Guangdong Pharmaceutical University Guangzhou China |
| Author_xml | – sequence: 1 givenname: Le‐xun surname: Wang fullname: Wang, Le‐xun organization: Guangdong Pharmaceutical University – sequence: 2 givenname: Sheng‐xi surname: Zhang fullname: Zhang, Sheng‐xi organization: Guangdong Pharmaceutical University – sequence: 3 givenname: Hui‐juan surname: Wu fullname: Wu, Hui‐juan organization: Guangdong Pharmaceutical University – sequence: 4 givenname: Xiang‐lu surname: Rong fullname: Rong, Xiang‐lu organization: Guangdong Pharmaceutical University – sequence: 5 givenname: Jiao surname: Guo fullname: Guo, Jiao email: gyguoyz@163.com organization: Guangdong Pharmaceutical University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30576000$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.4049/jimmunol.177.10.7303 10.1146/annurev-immunol-020711-075013 10.1038/srep19705 10.1038/ni.3153 10.1016/j.molimm.2011.04.016 10.1002/hep.28020 10.1016/j.brainres.2014.12.045 10.1016/j.bbrc.2017.09.053 10.1074/jbc.M111.327031 10.1007/978-4-431-55651-0_11 10.1038/nrcardio.2014.173 10.1172/JCI61716 10.4049/jimmunol.1002315 10.1189/jlb.72.1.101 10.1111/imr.12218 10.1093/jmcb/mjs044 10.1073/pnas.0809784106 10.4049/jimmunol.1200350 10.1172/JCI118598 10.1021/acsnano.6b06245 10.1016/j.cyto.2015.01.017 10.1038/nrd.2018.45 10.1038/nri1184 10.1016/j.molcel.2011.08.018 10.1084/jem.186.1.165 10.1093/cvr/cvt112 10.1016/j.radonc.2014.01.006 10.4049/jimmunol.1701515 10.4161/cc.21572 10.1160/TH16-08-0593 10.1016/j.imbio.2017.11.001 10.1371/journal.pone.0060086 10.1016/j.ijcard.2017.07.085 10.1016/j.clim.2014.02.016 10.1016/j.gene.2014.06.065 10.1038/cti.2016.59 10.1016/j.intimp.2012.08.009 10.1189/jlb.1005586 10.4049/jimmunol.152.10.4929 10.1371/journal.pone.0196950 10.1093/annonc/mdv474 10.1016/j.bbadis.2013.05.017 10.1016/j.cytogfr.2008.04.004 10.1016/j.plipres.2016.03.001 10.1200/JCO.2002.20.1.282 10.4049/jimmunol.1501369 10.1016/j.jdiacomp.2018.01.015 10.1371/journal.pone.0012828 10.4049/jimmunol.1601515 10.1016/j.expneurol.2007.06.009 10.1253/circj.CJ-14-0621 10.1371/journal.pone.0130713 10.1038/cr.2010.52 10.1016/j.immuni.2010.11.009 10.4049/jimmunol.167.11.6453 10.1016/j.cytogfr.2015.07.004 10.1080/2162402X.2017.1299301 10.1016/j.jsxm.2016.12.012 10.1002/hep.29885 10.1172/JCI200319246 10.1097/00000658-198810000-00010 10.1158/2159-8290.CD-16-0329 10.1016/j.radonc.2009.05.021 10.4049/jimmunol.139.9.3126 10.1007/s00011-015-0874-1 10.1038/nri3405 10.1371/journal.pone.0062465 10.1111/j.1582-4934.2005.tb00337.x 10.18632/oncotarget.4716 10.3389/fimmu.2018.01175 10.1038/ncomms4494 10.1186/s13195-015-0139-9 10.1371/journal.pone.0035994 10.1038/onc.2011.112 10.1002/eji.201041101 10.4049/jimmunol.179.12.8525 10.1002/jcp.26429 10.4049/jimmunol.1200662 10.2147/JAA.S104508 10.1189/jlb.0809590 10.1074/jbc.M114.599316 10.1172/JCI29881 10.1038/nsmb.2942 10.1182/blood-2007-02-072587 10.2174/187221309788489751 10.1002/jcb.26509 10.4049/jimmunol.180.9.6270 10.2337/db14-0298 10.1038/ni.3341 10.1189/jlb.0406249 10.1189/jlb.0212107 10.1042/bj2650621 10.1002/art.39694 10.3389/fimmu.2011.00033 10.4049/jimmunol.1601565 10.4049/jimmunol.143.9.2907 10.2217/imt-2018-0006 10.1002/jso.23110 10.1016/j.ajpath.2014.09.022 10.1038/nri2448 10.1128/MCB.00429-15 10.4049/jimmunol.1000017 10.4049/jimmunol.180.3.1938 10.5507/bp.2018.015 10.3390/ijms19061801 10.1038/ni.1920 10.1101/cshperspect.a016295 10.1371/journal.pone.0182075 10.3389/fimmu.2018.00444 10.1016/S0092-8674(01)00237-9 10.1002/eji.200939703 10.1038/cddis.2016.165 10.1111/j.1600-065X.2011.01061.x 10.1073/pnas.0605298103 10.1016/j.ajpath.2017.05.013 10.3892/mmr.2015.4503 10.1074/jbc.M112.426866 10.1371/journal.pone.0065542 10.1371/journal.pone.0104506 10.4049/jimmunol.0904016 10.1089/wound.2011.0307 10.3892/ijmm.2013.1260 10.1016/j.neurobiolaging.2015.05.016 10.1016/S0065-2776(08)60532-5 10.1523/JNEUROSCI.1220-13.2013 10.1016/j.immuni.2016.02.015 10.3389/fimmu.2017.01214 10.1016/j.imbio.2014.05.005 10.1042/AN20130045 10.1165/rcmb.2015-0077OC 10.1016/j.molimm.2015.01.023 10.1016/S1074-7613(00)80455-0 10.3748/wjg.v24.i11.1181 10.7150/ijbs.8879 10.1016/j.cell.2009.01.002 10.1038/nrm1104 10.1007/s10753-016-0405-4 10.1111/j.1471-4159.2009.06263.x 10.15252/embr.201643668 10.1038/nm.3467 10.1038/icb.2016.84 10.1038/nm1201-1291 10.1016/j.expneurol.2015.08.001 10.1161/CIRCULATIONAHA.111.087817 10.1038/ni.1990 10.2741/2692 10.1007/s12026-009-8150-5 10.1111/joim.12484 10.1089/nat.2016.0617 10.1177/0961203311434940 10.1016/j.it.2004.03.008 10.1016/j.immuni.2013.04.010 10.1089/neu.2012.2651 10.4049/jimmunol.0903935 10.1016/j.molimm.2016.08.007 10.1093/rheumatology/keh656 10.1159/000354228 10.1074/jbc.M115.683813 10.1189/jlb.1010553 10.1016/j.it.2004.09.015 10.1155/2015/816460 10.1074/jbc.M113.457218 10.1016/S1471-4906(03)00139-X 10.1016/j.cell.2008.12.027 |
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| Issue | 2 |
| Keywords | Autoimmunity Disease pathogenesis Monocyte/Macrophage Inflammation Manipulation of immune response Chemokines |
| Language | English |
| License | Attribution-NonCommercial https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model 2018 The Authors. Society for Leukocyte Biology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
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| PublicationDate | August 2019 |
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| References | 2010; 11 2012; 122 2018; 162 2015; 73 2004; 25 2018; 201 2009; 110 2010; 185 2010; 184 2012; 14 2012; 125 2012; 13 2013; 8 2016; 39 2012; 11 2006; 177 2014; 20 2018; 9 2010; 20 2007; 179 2009; 92 2013; 2013 2014; 13 2016; 279 2010; 5 2018; 32 2011; 244 2012; 21 2014; 10 2016; 44 2010; 33 2001; 167 2012; 189 2011; 2 2002; 72 2015; 1619 2018; 223 1994; 152 2017; 493 2001; 22 2016; 17 2014; 1842 2014; 152 1988; 208 2012; 106 2010; 40 2016; 13 1996; 97 2012; 30 2018; 24 2015; 195 2014; 547 2018; 19 2016; 5 2016; 6 2018; 17 2016; 7 2010; 47 2015; 62 2018; 119 2005; 9 2018; 233 1993; 54 2015; 65 2015; 2015 2003; 24 2011; 89 2014; 262 2018; 10 2016; 26 2016; 9 2006; 103 1998; 8 2018; 13 2009; 106 2015; 35 2017; 6 2015; 185 2017; 8 2015; 36 2012; 287 2012; 2012 2014; 219 2013; 288 2008; 8 2016; 71 2011; 12 2017; 198 2014; 63 1990; 265 2003; 112 2001; 104 2017; 117 2016; 77 2014; 5 2015; 290 2013; 99 2013; 13 1997; 186 1989; 143 2003; 3 2003; 4 2014; 9 2017; 245 2014; 6 2014; 289 2015; 12 2015; 6 2015; 16 2008; 19 2015; 10 2008; 209 2011; 30 2008; 13 2014; 110 2015; 7 2009; 136 2005; 44 2018; 68 2016; 55 2017; 95 2015; 273 2008; 180 2015; 26 2012; 92 2010; 87 2006; 80 2012; 1 2013; 38 2007; 117 2013; 33 2001; 7 1987; 139 2017; 14 2002; 20 2007; 110 2017; 11 2013; 31 2015; 22 2017; 12 2013; 30 2016; 65 2011; 41 2016; 62 2011; 43 2015 2017; 18 2011; 48 2017; 187 2009; 3 2012; 7 2012; 4 2014; 78 2016; 68 2011; 187 Gensel (2023032406362400800_jlb10302-cit-0006) 2015; 1619 Liu (2023032406362400800_jlb10302-cit-0143) 2018; 24 Chylikova (2023032406362400800_jlb10302-cit-0150) 2018; 162 Taganov (2023032406362400800_jlb10302-cit-0098) 2006; 103 Anderson (2023032406362400800_jlb10302-cit-0023) 2002; 72 Donnelly (2023032406362400800_jlb10302-cit-0144) 2008; 209 Tian (2023032406362400800_jlb10302-cit-0060) 2017; 8 Yu (2023032406362400800_jlb10302-cit-0103) 2015; 290 Eigsti (2023032406362400800_jlb10302-cit-0105) 2014; 289 Wu (2023032406362400800_jlb10302-cit-0022) 2012; 106 Gabriels (2023032406362400800_jlb10302-cit-0132) 2014; 110 Zhu (2023032406362400800_jlb10302-cit-0045) 2011; 244 Yue (2023032406362400800_jlb10302-cit-0024) 2017; 245 Lefevre (2023032406362400800_jlb10302-cit-0031) 2010; 5 Li (2023032406362400800_jlb10302-cit-0162) 2011; 30 Sudduth (2023032406362400800_jlb10302-cit-0070) 2013; 33 Chinetti-Gbaguidi (2023032406362400800_jlb10302-cit-0005) 2015; 12 Bohm (2023032406362400800_jlb10302-cit-0068) 2013; 99 Pyne (2023032406362400800_jlb10302-cit-0064) 2016; 62 Miller (2023032406362400800_jlb10302-cit-0036) 1989; 143 Huang (2023032406362400800_jlb10302-cit-0110) 2016; 6 Wilcock (2023032406362400800_jlb10302-cit-0147) 2014; 13 Chen (2023032406362400800_jlb10302-cit-0166) 2011; 48 Locksley (2023032406362400800_jlb10302-cit-0074) 2001; 104 Liu (2023032406362400800_jlb10302-cit-0028) 2015; 62 Heinrich (2023032406362400800_jlb10302-cit-0086) 1990; 265 MacParland (2023032406362400800_jlb10302-cit-0140) 2017; 11 Pearson (2023032406362400800_jlb10302-cit-0119) 2001; 22 Rothfuchs (2023032406362400800_jlb10302-cit-0133) 2001; 167 Cai (2023032406362400800_jlb10302-cit-0099) 2012; 4 Jiang (2023032406362400800_jlb10302-cit-0042) 2016; 9 del Rio (2023032406362400800_jlb10302-cit-0051) 2010; 87 Cao (2023032406362400800_jlb10302-cit-0113) 2016; 13 Herndon (2023032406362400800_jlb10302-cit-0169) 1988; 208 Liu (2023032406362400800_jlb10302-cit-0056) 2008; 180 Shapouri-Moghaddam (2023032406362400800_jlb10302-cit-0008) 2018; 233 Duluc (2023032406362400800_jlb10302-cit-0017) 2007; 110 Chen (2023032406362400800_jlb10302-cit-0052) 1994; 152 Zhou (2023032406362400800_jlb10302-cit-0145) 2009; 110 Li (2023032406362400800_jlb10302-cit-0165) 2015; 65 Kobayashi (2023032406362400800_jlb10302-cit-0050) 2012; 189 Matsui (2023032406362400800_jlb10302-cit-0055) 2017; 14 Perdiguero (2023032406362400800_jlb10302-cit-0003) 2016; 17 De Paoli (2023032406362400800_jlb10302-cit-0012) 2014; 78 Frodermann (2023032406362400800_jlb10302-cit-0076) 2016; 279 Bai (2023032406362400800_jlb10302-cit-0160) 2015; 6 Edwards (2023032406362400800_jlb10302-cit-0034) 2006; 80 Ramkhelawon (2023032406362400800_jlb10302-cit-0153) 2014; 20 Arora (2023032406362400800_jlb10302-cit-0010) 2018; 223 Zhang (2023032406362400800_jlb10302-cit-0032) 2015; 273 Qiao (2023032406362400800_jlb10302-cit-0167) 2005; 44 Kobayashi (2023032406362400800_jlb10302-cit-0136) 2011; 89 Song (2023032406362400800_jlb10302-cit-0121) 2005; 9 Filardy (2023032406362400800_jlb10302-cit-0139) 2010; 185 Zhuang (2023032406362400800_jlb10302-cit-0102) 2012; 125 Asai (2023032406362400800_jlb10302-cit-0040) 2012; 92 Bumgardner (2023032406362400800_jlb10302-cit-0091) 2018; 13 Thompson (2023032406362400800_jlb10302-cit-0146) 2013; 30 Chen (2023032406362400800_jlb10302-cit-0053) 2013; 13 Lumeng (2023032406362400800_jlb10302-cit-0152) 2007; 117 Sung (2023032406362400800_jlb10302-cit-0093) 2017; 198 Colin (2023032406362400800_jlb10302-cit-0011) 2014; 262 Ortiz (2023032406362400800_jlb10302-cit-0077) 2015; 10 Lawrence (2023032406362400800_jlb10302-cit-0114) 2001; 7 Lan (2023032406362400800_jlb10302-cit-0066) 2018; 68 Schiffer (2023032406362400800_jlb10302-cit-0142) 2008; 180 Wen (2023032406362400800_jlb10302-cit-0168) 2012; 21 Akira (2023032406362400800_jlb10302-cit-0087) 1993; 54 Leibowitz (2023032406362400800_jlb10302-cit-0129) 2014; 5 Schulert (2023032406362400800_jlb10302-cit-0090) 2016; 68 Yeligar (2023032406362400800_jlb10302-cit-0155) 2016; 55 Cai (2023032406362400800_jlb10302-cit-0088) 2013; 8 Nazari-Jahantigh (2023032406362400800_jlb10302-cit-0100) 2012; 122 Hedrich (2023032406362400800_jlb10302-cit-0033) 2010; 47 Chen (2023032406362400800_jlb10302-cit-0163) 2016; 6 Mantovani (2023032406362400800_jlb10302-cit-0004) 2004; 25 Schaper (2023032406362400800_jlb10302-cit-0082) 2015; 26 Mulder (2023032406362400800_jlb10302-cit-0061) 2014; 219 Ishizuka (2023032406362400800_jlb10302-cit-0057) 2012; 14 Bonizzi (2023032406362400800_jlb10302-cit-0116) 2004; 25 Kobayashi (2023032406362400800_jlb10302-cit-0138) 2017; 187 Ito (2023032406362400800_jlb10302-cit-0043) 2017; 493 Russell (2023032406362400800_jlb10302-cit-0131) 2009; 92 Kobayashi (2023032406362400800_jlb10302-cit-0137) 2010; 185 McCully (2023032406362400800_jlb10302-cit-0038) 2011; 2 Walker (2023032406362400800_jlb10302-cit-0092) 2015; 7 Sun (2023032406362400800_jlb10302-cit-0112) 2017; 18 Pedrazzi (2023032406362400800_jlb10302-cit-0170) 2007; 179 Suzuki (2023032406362400800_jlb10302-cit-0049) 2018; 201 Asai (2023032406362400800_jlb10302-cit-0025) 2017; 6 Wang (2023032406362400800_jlb10302-cit-0106) 2011; 43 Ambarus (2023032406362400800_jlb10302-cit-0014) 2012; 7 Rojas (2023032406362400800_jlb10302-cit-0062) 2015; 2015 Dorresteijn (2023032406362400800_jlb10302-cit-0130) 2002; 20 Orme (2023032406362400800_jlb10302-cit-0041) 2012; 13 Mattick (2023032406362400800_jlb10302-cit-0107) 2015; 22 Reddy (2023032406362400800_jlb10302-cit-0109) 2014; 63 Elcombe (2023032406362400800_jlb10302-cit-0047) 2013; 8 Basu Mallik (2023032406362400800_jlb10302-cit-0154) 2018; 32 Chen (2023032406362400800_jlb10302-cit-0079) 2013; 8 Garbers (2023032406362400800_jlb10302-cit-0083) 2018; 17 Liberale (2023032406362400800_jlb10302-cit-0063) 2017; 117 Xiao (2023032406362400800_jlb10302-cit-0078) 2014; 547 Krausgruber (2023032406362400800_jlb10302-cit-0126) 2011; 12 Nakamura (2023032406362400800_jlb10302-cit-0141) 2015; 73 Zhang (2023032406362400800_jlb10302-cit-0080) 2013; 288 Li (2023032406362400800_jlb10302-cit-0059) 2016; 39 Gabriel (2023032406362400800_jlb10302-cit-0067) 2017; 12 Pereira (2023032406362400800_jlb10302-cit-0054) 2009; 3 Weisberg (2023032406362400800_jlb10302-cit-0151) 2003; 112 Wynn (2023032406362400800_jlb10302-cit-0013) 2016; 44 Wilcock (2023032406362400800_jlb10302-cit-0148) 2015; 36 Fukao (2023032406362400800_jlb10302-cit-0122) 2003; 24 Chen (2023032406362400800_jlb10302-cit-0108) 2015; 35 Xiao (2023032406362400800_jlb10302-cit-0094) 2009; 136 Tsuchimoto (2023032406362400800_jlb10302-cit-0029) 2015; 195 Zhao (2023032406362400800_jlb10302-cit-0125) 2014; 9 Ye (2023032406362400800_jlb10302-cit-0111) 2018; 119 Tamura (2023032406362400800_jlb10302-cit-0157) 2018; 10 Mauri (2023032406362400800_jlb10302-cit-0044) 1998; 8 Brand (2023032406362400800_jlb10302-cit-0115) 1996; 97 Martinez (2023032406362400800_jlb10302-cit-0001) 2008; 13 Szanto (2023032406362400800_jlb10302-cit-0156) 2010; 33 Wang (2023032406362400800_jlb10302-cit-0018) 2010; 20 Li (2023032406362400800_jlb10302-cit-0161) 2018; 9 Atri (2023032406362400800_jlb10302-cit-0020) 2018; 19 Lee (2023032406362400800_jlb10302-cit-0149) 2014; 1842 Sunakawa (2023032406362400800_jlb10302-cit-0021) 2015; 26 Satoh (2023032406362400800_jlb10302-cit-0128) 2010; 11 Nie (2023032406362400800_jlb10302-cit-0101) 2016; 7 Lopez-Pelaez (2023032406362400800_jlb10302-cit-0124) 2011; 41 Wilcock (2023032406362400800_jlb10302-cit-0071) 2012; 2012 Aggarwal (2023032406362400800_jlb10302-cit-0073) 2003; 3 Kono (2023032406362400800_jlb10302-cit-0048) 2016; 71 Liu (2023032406362400800_jlb10302-cit-0127) 2014; 10 Roszer (2023032406362400800_jlb10302-cit-0015) 2015; 2015 Troutman (2023032406362400800_jlb10302-cit-0123) 2012; 11 Zhang (2023032406362400800_jlb10302-cit-0097) 2013; 31 Banerjee (2023032406362400800_jlb10302-cit-0104) 2013; 288 Graff (2023032406362400800_jlb10302-cit-0007) 2012; 287 Lisi (2023032406362400800_jlb10302-cit-0158) 2014; 6 Fujiwara (2023032406362400800_jlb10302-cit-0164) 2016; 5 Kishimoto (2023032406362400800_jlb10302-cit-0085) 2015 Zhang (2023032406362400800_jlb10302-cit-0089) 2011; 187 Ferrante (2023032406362400800_jlb10302-cit-0019) 2012; 1 Lefevre (2023032406362400800_jlb10302-cit-0030) 2013; 38 Kasper (2023032406362400800_jlb10302-cit-0065) 2010; 40 Zizzo (2023032406362400800_jlb10302-cit-0016) 2012; 189 Ohlsson (2023032406362400800_jlb10302-cit-0075) 2014; 152 O'Connell (2023032406362400800_jlb10302-cit-0095) 2012; 30 Salomon (2023032406362400800_jlb10302-cit-0072) 2018; 9 da Fonseca (2023032406362400800_jlb10302-cit-0159) 2013; 2013 Bashir (2023032406362400800_jlb10302-cit-0009) 2016; 65 Zhang (2023032406362400800_jlb10302-cit-0118) 2010; 184 Bartel (2023032406362400800_jlb10302-cit-0096) 2009; 136 Sironi (2023032406362400800_jlb10302-cit-0039) 2006; 80 Ito (2023032406362400800_jlb10302-cit-0027) 2016; 26 Hunter (2023032406362400800_jlb10302-cit-0081) 2015; 16 Porta (2023032406362400800_jlb10302-cit-0117) 2009; 106 Vergadi (2023032406362400800_jlb10302-cit-0120) 2017; 198 Mosser (2023032406362400800_jlb10302-cit-0002) 2008; 8 Tiffany (2023032406362400800_jlb10302-cit-0037) 1997; 186 Martinez (2023032406362400800_jlb10302-cit-0069) 2006; 177 Li (2023032406362400800_jlb10302-cit-0058) 2016; 77 Nishiguchi (2023032406362400800_jlb10302-cit-0026) 2017; 95 Tanaka (2023032406362400800_jlb10302-cit-0084) 2014; 6 Rosenberger (2023032406362400800_jlb10302-cit-0134) 2003; 4 Burd (2023032406362400800_jlb10302-cit-0035) 1987; 139 Ohama (2023032406362400800_jlb10302-cit-0135) 2015; 185 Yu (2023032406362400800_jlb10302-cit-0046) 2008; 19 |
| References_xml | – volume: 125 start-page: 2892 year: 2012 end-page: 2903 article-title: A novel regulator of macrophage activation: miR‐223 in obesity‐associated adipose tissue inflammation publication-title: Circulation – volume: 30 start-page: 295 year: 2012 end-page: 312 article-title: microRNA regulation of inflammatory responses publication-title: Annu Rev Immunol – volume: 8 year: 2013 article-title: Granulin exacerbates lupus nephritis via enhancing macrophage M2b polarization publication-title: Plos One – volume: 44 start-page: 1108 year: 2005 end-page: 1114 article-title: Induction of systemic lupus erythematosus‐like syndrome in syngeneic mice by immunization with activated lymphocyte‐derived DNA publication-title: Rheumatology (Oxford) – volume: 273 start-page: 83 year: 2015 end-page: 91 article-title: Age decreases macrophage IL‐10 expression: implications for functional recovery and tissue repair in spinal cord injury publication-title: Exp Neurol – volume: 117 start-page: 7 year: 2017 end-page: 18 article-title: Pathophysiological relevance of macrophage subsets in atherogenesis publication-title: Thromb Haemost – volume: 5 year: 2016 article-title: Guanylate‐binding protein 5 is a marker of interferon‐gamma‐induced classically activated macrophages publication-title: Clin Transl Immunology – volume: 7 year: 2016 article-title: MicroRNA‐155 facilitates skeletal muscle regeneration by balancing pro‐ and anti‐inflammatory macrophages publication-title: Cell Death Dis – volume: 13 start-page: 453 year: 2008 end-page: 461 article-title: Macrophage activation and polarization publication-title: Front Biosci – volume: 13 start-page: 227 year: 2013 end-page: 242 article-title: Molecular mechanisms of T cell co‐stimulation and co‐inhibition publication-title: Nat Rev Immunol – volume: 2015 start-page: 851252 year: 2015 article-title: Macrophage heterogeneity and plasticity: impact of macrophage biomarkers on atherosclerosis publication-title: Scientifica (Cairo) – volume: 9 start-page: 444 year: 2018 article-title: Tumor necrosis factor alpha and regulatory T cells in oncoimmunology publication-title: Front Immunol – volume: 10 start-page: 899 year: 2018 end-page: 909 article-title: Dual role of macrophage in tumor immunity publication-title: Immunotherapy – volume: 26 start-page: 2450 year: 2015 end-page: 2456 article-title: Variations in genes regulating tumor‐associated macrophages (TAMs) to predict outcomes of bevacizumab‐based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials publication-title: Ann Oncol – volume: 167 start-page: 6453 year: 2001 end-page: 6461 article-title: IFN‐alpha beta‐dependent, IFN‐gamma secretion by bone marrow‐derived macrophages controls an intracellular bacterial infection publication-title: J Immunol – volume: 189 start-page: 3508 year: 2012 end-page: 3520 article-title: Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction publication-title: J Immunol – volume: 187 start-page: 1764 year: 2011 end-page: 1777 article-title: Macrophage differentiation and polarization via phosphatidylinositol 3‐kinase/Akt‐ERK signaling pathway conferred by serum amyloid P component publication-title: J Immunol – volume: 80 start-page: 342 year: 2006 end-page: 349 article-title: Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2) publication-title: J Leukoc Biol – volume: 106 start-page: 14978 year: 2009 end-page: 14983 article-title: Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB publication-title: Proc Natl Acad Sci U S A – volume: 20 start-page: 282 year: 2002 end-page: 288 article-title: Increased risk of ischemic stroke after radiotherapy on the neck in patients younger than 60 years publication-title: J Clin Oncol – volume: 11 start-page: 2428 year: 2017 end-page: 2443 article-title: Phenotype determines nanoparticle uptake by human macrophages from liver and blood publication-title: ACS Nano – volume: 30 start-page: 3887 year: 2011 end-page: 3899 article-title: Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor‐2 publication-title: Oncogene – volume: 103 start-page: 12481 year: 2006 end-page: 12486 article-title: NF‐kappaB‐dependent induction of microRNA miR‐146, an inhibitor targeted to signaling proteins of innate immune responses publication-title: Proc Natl Acad Sci U S A – volume: 209 start-page: 378 year: 2008 end-page: 388 article-title: Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury publication-title: Exp Neurol – volume: 245 start-page: 228 year: 2017 end-page: 235 article-title: M2b macrophages reduce early reperfusion injury after myocardial ischemia in mice: a predominant role of inhibiting apoptosis via A20 publication-title: Int J Cardiol – volume: 8 year: 2013 article-title: Dectin‐1 regulates IL‐10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers publication-title: Plos One – volume: 177 start-page: 7303 year: 2006 end-page: 7311 article-title: Transcriptional profiling of the human monocyte‐to‐macrophage differentiation and polarization: new molecules and patterns of gene expression publication-title: J Immunol – volume: 219 start-page: 737 year: 2014 end-page: 745 article-title: Spleen‐derived macrophages are readily polarized into classically activated (M1) or alternatively activated (M2) states publication-title: Immunobiology – volume: 4 start-page: 385 year: 2003 end-page: 396 article-title: Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens publication-title: Nat Rev Mol Cell Biol – volume: 9 start-page: 59 year: 2005 end-page: 71 article-title: The activation of Akt/PKB signaling pathway and cell survival publication-title: J Cell Mol Med – volume: 288 start-page: 13534 year: 2013 end-page: 13550 article-title: DNA‐dependent activator of interferon‐regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway publication-title: J Biol Chem – volume: 1842 start-page: 446 year: 2014 end-page: 462 article-title: Cellular and molecular players in adipose tissue inflammation in the development of obesity‐induced insulin resistance publication-title: Biochim Biophys Acta – volume: 187 start-page: 1998 year: 2017 end-page: 2007 article-title: Short‐term alcohol abstinence improves antibacterial defenses of chronic alcohol‐consuming mice against gut bacteria‐associated sepsis caused by enterococcus faecalis oral infection publication-title: Am J Pathol – volume: 68 start-page: 2300 year: 2016 end-page: 2313 article-title: Monocyte microRNA expression in active systemic juvenile idiopathic arthritis implicates microRNA‐125a‐5p in polarized monocyte phenotypes publication-title: Arthritis Rheumatol – volume: 38 start-page: 1038 year: 2013 end-page: 1049 article-title: The C‐type lectin receptors dectin‐1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum publication-title: Immunity – volume: 139 start-page: 3126 year: 1987 end-page: 3131 article-title: Cloning and characterization of a novel T cell activation gene publication-title: J Immunol – volume: 6 start-page: 19705 year: 2016 article-title: Identification of differentially expressed long non‐coding RNAs in polarized macrophages publication-title: Sci Rep – volume: 72 start-page: 101 year: 2002 end-page: 106 article-title: A novel phenotype for an activated macrophage: the type 2 activated macrophage publication-title: J Leukoc Biol – volume: 104 start-page: 487 year: 2001 end-page: 501 article-title: The TNF and TNF receptor superfamilies: integrating mammalian biology publication-title: Cell – volume: 3 start-page: 745 year: 2003 end-page: 756 article-title: Signalling pathways of the TNF superfamily: a double‐edged sword publication-title: Nat Rev Immunol – volume: 62 start-page: 93 year: 2016 end-page: 106 article-title: Sphingosine 1‐phosphate and sphingosine kinases in health and disease: recent advances publication-title: Prog Lipid Res – volume: 290 start-page: 28286 year: 2015 end-page: 28298 article-title: Long non‐coding RNA growth arrest‐specific transcript 5 (GAS5) inhibits liver fibrogenesis through a mechanism of competing endogenous RNA publication-title: J Biol Chem – volume: 22 start-page: 153 year: 2001 end-page: 183 article-title: Mitogen‐activated protein (MAP) kinase pathways: regulation and physiological functions publication-title: Endocr Rev – volume: 11 start-page: 936 year: 2010 end-page: 944 article-title: The Jmjd3‐Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection publication-title: Nat Immunol – volume: 162 start-page: 79 year: 2018 end-page: 82 article-title: M1/M2 macrophage polarization in human obese adipose tissue publication-title: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub – volume: 33 start-page: 699 year: 2010 end-page: 712 article-title: STAT6 transcription factor is a facilitator of the nuclear receptor PPAR gamma‐regulated gene expression in macrophages and dendritic cells publication-title: Immunity – volume: 287 start-page: 21816 year: 2012 end-page: 21825 article-title: Identifying functional microRNAs in macrophages with polarized phenotypes publication-title: J Biol Chem – volume: 223 start-page: 383 year: 2018 end-page: 396 article-title: Macrophages: their role, activation and polarization in pulmonary diseases publication-title: Immunobiology – volume: 119 start-page: 2951 year: 2018 end-page: 2963 article-title: Long non‐coding RNA cox‐2 prevents immune evasion and metastasis of hepatocellular carcinoma by altering M1/M2 macrophage polarization publication-title: J Cell Biochem – volume: 4 start-page: 341 year: 2012 end-page: 343 article-title: Re‐polarization of tumor‐associated macrophages to pro‐inflammatory M1 macrophages by microRNA‐155 publication-title: J Mol Cell Biol – volume: 97 start-page: 1715 year: 1996 end-page: 1722 article-title: Activated transcription factor nuclear factor‐kappa B is present in the atherosclerotic lesion publication-title: J Clin Invest – volume: 55 start-page: 35 year: 2016 end-page: 46 article-title: Peroxisome proliferator‐activated receptor gamma regulates chronic alcohol‐induced alveolar macrophage dysfunction publication-title: Am J Respir Cell Mol Biol – volume: 48 start-page: 1532 year: 2011 end-page: 1539 article-title: Blockade of TLR9 signaling in B cells impaired anti‐dsDNA antibody production in mice induced by activated syngenic lymphocyte‐derived DNA immunization publication-title: Mol Immunol – volume: 233 start-page: 6425 year: 2018 end-page: 6440 article-title: Macrophage plasticity, polarization, and function in health and disease publication-title: J Cell Physiol – volume: 99 start-page: 505 year: 2013 end-page: 513 article-title: Factor‐Xa‐induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells publication-title: Cardiovasc Res – volume: 9 start-page: 101 year: 2016 end-page: 107 article-title: Update on the role of alternatively activated macrophages in asthma publication-title: J Asthma Allergy – volume: 8 start-page: 21 year: 1998 end-page: 30 article-title: LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator publication-title: Immunity – volume: 2012 start-page: 495243 year: 2012 article-title: A changing perspective on the role of neuroinflammation in Alzheimer's disease publication-title: Int J Alzheimers Dis – volume: 195 start-page: 5169 year: 2015 end-page: 5177 article-title: M2b monocytes provoke bacterial pneumonia and gut bacteria‐associated sepsis in alcoholics publication-title: J Immunol – volume: 92 start-page: 859 year: 2012 end-page: 867 article-title: CCL1 released from M2b macrophages is essentially required for the maintenance of their properties publication-title: J Leukoc Biol – volume: 68 start-page: 1070 year: 2018 end-page: 1086 article-title: Sphingosine kinase 1 promotes liver fibrosis by preventing miR‐19b‐3p‐mediated inhibition of CCR2 publication-title: Hepatology – volume: 208 start-page: 484 year: 1988 end-page: 492 article-title: Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients publication-title: Ann Surg – volume: 6 start-page: 25295 year: 2015 end-page: 25307 article-title: Contact‐dependent carcinoma aggregate dispersion by M2a macrophages via ICAM‐1 and beta2 integrin interactions publication-title: Oncotarget – volume: 185 start-page: 7174 year: 2010 end-page: 7179 article-title: M2b monocytes predominated in peripheral blood of severely burned patients publication-title: J Immunol – volume: 180 start-page: 1938 year: 2008 end-page: 1947 article-title: Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis publication-title: J Immunol – volume: 62 start-page: 1779 year: 2015 end-page: 1790 article-title: Chemokine (C‐X‐C motif) receptor 3‐positive B cells link interleukin‐17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma publication-title: Hepatology – volume: 5 year: 2010 article-title: PPARgamma ligands switched high fat diet‐induced macrophage M2b polarization toward M2a thereby improving intestinal elimination publication-title: Plos One – volume: 19 start-page: 285 year: 2008 end-page: 294 article-title: Targeting tumors with LIGHT to generate metastasis‐clearing immunity publication-title: Cytokine Growth Factor Rev – volume: 73 start-page: 8 year: 2015 end-page: 15 article-title: Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype publication-title: Cytokine – volume: 1619 start-page: 1 year: 2015 end-page: 11 article-title: Macrophage activation and its role in repair and pathology after spinal cord injury publication-title: Brain Res – volume: 30 start-page: 1311 year: 2013 end-page: 1324 article-title: The therapeutic role of interleukin‐10 after spinal cord injury publication-title: J Neurotrauma – volume: 17 start-page: 2 year: 2016 end-page: 8 article-title: The development and maintenance of resident macrophages publication-title: Nat Immunol – volume: 152 start-page: 4929 year: 1994 end-page: 4936 article-title: Molecular cloning and expression of early T cell costimulatory molecule‐1 and its characterization as B7‐2 molecule publication-title: J Immunol – volume: 31 start-page: 797 year: 2013 end-page: 802 article-title: Expression profiles of miRNAs in polarized macrophages publication-title: Int J Mol Med – volume: 13 start-page: 151 year: 2012 end-page: 158 article-title: Macrophage subpopulations in systemic lupus erythematosus publication-title: Discov Med – volume: 136 start-page: 26 year: 2009 end-page: 36 article-title: MicroRNA control in the immune system: basic principles publication-title: Cell – volume: 117 start-page: 175 year: 2007 end-page: 184 article-title: Obesity induces a phenotypic switch in adipose tissue macrophage polarization publication-title: J Clin Invest – volume: 12 start-page: 10 year: 2015 end-page: 17 article-title: Macrophage subsets in atherosclerosis publication-title: Nat Rev Cardiol – volume: 24 start-page: 1181 year: 2018 end-page: 1195 article-title: Functional macrophages and gastrointestinal disorders publication-title: World J Gastroenterol – volume: 189 start-page: 296 year: 2012 end-page: 303 article-title: Role of M2b macrophages in the acceleration of bacterial translocation and subsequent sepsis in mice exposed to whole body [137Cs] gamma‐irradiation publication-title: J Immunol – volume: 1 start-page: 10 year: 2012 end-page: 16 article-title: Regulation of macrophage polarization and wound healing publication-title: Adv Wound Care (New Rochelle) – volume: 11 start-page: 3559 year: 2012 end-page: 3567 article-title: Toll‐like receptors, signaling adapters and regulation of the pro‐inflammatory response by PI3K publication-title: Cell Cycle – volume: 26 start-page: 269 year: 2016 end-page: 276 article-title: The polarization of M2b monocytes in cultures of burn patient peripheral CD14(+) cells treated with a selected human CCL1 antisense oligodeoxynucleotide publication-title: Nucleic Acid Ther – volume: 7 year: 2012 article-title: Soluble immune complexes shift the TLR‐induced cytokine production of distinct polarized human macrophage subsets towards IL‐10 publication-title: Plos One – volume: 41 start-page: 1733 year: 2011 end-page: 1741 article-title: Cot/tpl2 activity is required for TLR‐induced activation of the Akt p70 S6k pathway in macrophages: implications for NO synthase 2 expression publication-title: Eur J Immunol – volume: 71 start-page: 619 year: 2016 end-page: 624 article-title: Dextran sodium sulfate alters cytokine production in macrophages in vitro publication-title: Pharmazie – volume: 7 start-page: 1291 year: 2001 end-page: 1297 article-title: Possible new role for NF‐kappaB in the resolution of inflammation publication-title: Nat Med – volume: 32 start-page: 524 year: 2018 end-page: 530 article-title: Epigenetic modulation of macrophage polarization‐ perspectives in diabetic wounds publication-title: J Diabetes Complications – volume: 13 start-page: 183 year: 2014 end-page: 185 article-title: Neuroinflammatory phenotypes and their roles in Alzheimer's disease publication-title: Neurodegener Dis – volume: 3 start-page: 128 year: 2009 end-page: 131 article-title: Dynamics of CD86 expression on allergic inflammation–new insights publication-title: Recent Pat Inflamm Allergy Drug Discov – volume: 8 year: 2013 article-title: Mannose‐binding lectin blunts macrophage polarization and ameliorates lupus nephritis publication-title: Plos One – volume: 92 start-page: 477 year: 2009 end-page: 483 article-title: Novel insights into pathological changes in muscular arteries of radiotherapy patients publication-title: Radiother Oncol – volume: 289 start-page: 28433 year: 2014 end-page: 28447 article-title: Regulation of activation‐associated microRNA accumulation rates during monocyte‐to‐macrophage differentiation publication-title: J Biol Chem – volume: 262 start-page: 153 year: 2014 end-page: 166 article-title: Macrophage phenotypes in atherosclerosis publication-title: Immunol Rev – volume: 18 start-page: 1801 year: 2017 end-page: 1816 article-title: LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination publication-title: EMBO Rep – volume: 493 start-page: 170 year: 2017 end-page: 175 article-title: M2b macrophage polarization accompanied with reduction of long noncoding RNA GAS5 publication-title: Biochem Biophys Res Commun – volume: 87 start-page: 223 year: 2010 end-page: 235 article-title: HVEM/LIGHT/BTLA/CD160 cosignaling pathways as targets for immune regulation publication-title: J Leukoc Biol – volume: 2015 start-page: 816460 year: 2015 article-title: Understanding the mysterious M2 macrophage through activation markers and effector mechanisms publication-title: Mediators Inflamm – volume: 180 start-page: 6270 year: 2008 end-page: 6278 article-title: Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo publication-title: J Immunol – volume: 198 start-page: 2589 year: 2017 end-page: 2601 article-title: Dependence of glomerulonephritis induction on novel intraglomerular alternatively activated bone marrow‐derived macrophages and Mac‐1 and PD‐L1 in lupus‐prone NZM2328 mice publication-title: J Immunol – volume: 112 start-page: 1796 year: 2003 end-page: 1808 article-title: Obesity is associated with macrophage accumulation in adipose tissue publication-title: J Clin Invest – volume: 186 start-page: 165 year: 1997 end-page: 170 article-title: Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I‐309 publication-title: J Exp Med – volume: 89 start-page: 797 year: 2011 end-page: 803 article-title: Propranolol as a modulator of M2b monocytes in severely burned patients publication-title: J Leukoc Biol – volume: 6 year: 2017 article-title: Host antitumor resistance improved by the macrophage polarization in a chimera model of patients with HCC publication-title: Oncoimmunology – volume: 110 start-page: 455 year: 2014 end-page: 460 article-title: Irradiation of existing atherosclerotic lesions increased inflammation by favoring pro‐inflammatory macrophages publication-title: Radiother Oncol – volume: 33 start-page: 9684 year: 2013 end-page: 9692 article-title: Intracranial injection of Gammagard, a human IVIg, modulates the inflammatory response of the brain and lowers Abeta in APP/PS1 mice along a different time course than anti‐Abeta antibodies publication-title: J Neurosci – volume: 265 start-page: 621 year: 1990 end-page: 636 article-title: Interleukin‐6 and the acute phase response publication-title: Biochem J – volume: 10 year: 2015 article-title: Neisseria gonorrhoeae modulates immunity by polarizing human macrophages to a M2 profile publication-title: Plos One – volume: 39 start-page: 1704 year: 2016 end-page: 1717 article-title: Nanoparticle‐delivered IRF5 siRNA facilitates M1 to M2 transition, reduces demyelination and neurofilament loss, and promotes functional recovery after spinal cord injury in mice publication-title: Inflammation – volume: 2013 start-page: 264124 year: 2013 article-title: Microglia and macrophages in malignant gliomas: recent discoveries and implications for promising therapies publication-title: Clin Dev Immunol – volume: 6 start-page: 1182 year: 2016 end-page: 1195 article-title: Polarization of tissue‐resident TFH‐like cells in human hepatoma bridges innate monocyte inflammation and M2b macrophage polarization publication-title: Cancer Discov – volume: 12 start-page: 231 year: 2011 end-page: 238 article-title: IRF5 promotes inflammatory macrophage polarization and TH1‐TH17 responses publication-title: Nat Immunol – volume: 77 start-page: 205 year: 2016 end-page: 212 article-title: MiR‐146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA publication-title: Mol Immunol – volume: 20 start-page: 377 year: 2014 end-page: 384 article-title: Netrin‐1 promotes adipose tissue macrophage retention and insulin resistance in obesity publication-title: Nat Med – volume: 6 start-page: 171 year: 2014 end-page: 183 article-title: Proinflammatory‐activated glioma cells induce a switch in microglial polarization and activation status, from a predominant M2b phenotype to a mixture of M1 and M2a/B polarized cells publication-title: ASN Neuro – volume: 136 start-page: 215 year: 2009 end-page: 233 article-title: MicroRNAs: target recognition and regulatory functions publication-title: Cell – volume: 2 start-page: 33 year: 2011 article-title: The human cutaneous chemokine system publication-title: Front Immunol – volume: 40 start-page: 1162 year: 2010 end-page: 1173 article-title: CXCL4‐induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1 publication-title: Eur J Immunol – volume: 198 start-page: 1006 year: 2017 end-page: 1014 article-title: Akt signaling pathway in macrophage activation and M1/M2 polarization publication-title: J Immunol – volume: 63 start-page: 4249 year: 2014 end-page: 4261 article-title: Regulation of inflammatory phenotype in macrophages by a diabetes‐induced long noncoding RNA publication-title: Diabetes – volume: 80 start-page: 1298 year: 2006 end-page: 1307 article-title: Biochemical and functional characterization of three activated macrophage populations publication-title: J Leukoc Biol – volume: 143 start-page: 2907 year: 1989 end-page: 2916 article-title: A novel polypeptide secreted by activated human T lymphocytes publication-title: J Immunol – volume: 16 start-page: 448 year: 2015 end-page: 457 article-title: IL‐6 as a keystone cytokine in health and disease publication-title: Nat Immunol – volume: 26 start-page: 475 year: 2015 end-page: 487 article-title: Interleukin‐6: biology, signaling and strategies of blockade publication-title: Cytokine Growth Factor Rev – volume: 110 start-page: 4319 year: 2007 end-page: 4330 article-title: Tumor‐associated leukemia inhibitory factor and IL‐6 skew monocyte differentiation into tumor‐associated macrophage‐like cells publication-title: Blood – volume: 5 start-page: 3494 year: 2014 article-title: Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice publication-title: Nat Commun – volume: 185 start-page: 2044 year: 2010 end-page: 2050 article-title: Proinflammatory clearance of apoptotic neutrophils induces an IL‐12(low)IL‐10(high) regulatory phenotype in macrophages publication-title: J Immunol – volume: 36 start-page: 2468 year: 2015 end-page: 2474 article-title: Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease publication-title: Neurobiol Aging – volume: 8 start-page: 1214 year: 2017 article-title: Cannabinoid receptor 1 participates in liver inflammation by promoting M1 macrophage polarization via RhoA/NF‐kappaB p65 and ERK1/2 pathways, respectively, in mouse liver fibrogenesis publication-title: Front Immunol – volume: 95 start-page: 198 year: 2017 end-page: 206 article-title: Macrophage polarization and MRSA infection in burned mice publication-title: Immunol Cell Biol – volume: 17 start-page: 395 year: 2018 end-page: 412 article-title: Interleukin‐6: designing specific therapeutics for a complex cytokine publication-title: Nat Rev Drug Discov – volume: 13 start-page: 27 year: 2016 end-page: 34 article-title: Long non‐coding RNA‐GAS5 acts as a tumor suppressor in bladder transitional cell carcinoma via regulation of chemokine (C‐C motif) ligand 1 expression publication-title: Mol Med Rep – volume: 10 start-page: 520 year: 2014 end-page: 529 article-title: Macrophage polarization in inflammatory diseases publication-title: Int J Biol Sci – volume: 184 start-page: 6465 year: 2010 end-page: 6478 article-title: Blockade of Notch1 signaling alleviates murine lupus via blunting macrophage activation and M2b polarization publication-title: J Immunol – volume: 179 start-page: 8525 year: 2007 end-page: 8532 article-title: Selective proinflammatory activation of astrocytes by high‐mobility group box 1 protein signaling publication-title: J Immunol – volume: 152 start-page: 10 year: 2014 end-page: 19 article-title: Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization publication-title: Clin Immunol – volume: 24 start-page: 358 year: 2003 end-page: 363 article-title: PI3K and negative regulation of TLR signaling publication-title: Trends Immunol – volume: 9 year: 2014 article-title: PI3K/Akt signaling pathway modulates influenza virus induced mouse alveolar macrophage polarization to M1/M2b publication-title: Plos One – volume: 110 start-page: 1617 year: 2009 end-page: 1627 article-title: Interleukin‐10 provides direct trophic support to neurons publication-title: J Neurochem – volume: 43 start-page: 904 year: 2011 end-page: 914 article-title: Molecular mechanisms of long noncoding RNAs publication-title: Mol Cell – volume: 47 start-page: 185 year: 2010 end-page: 206 article-title: Cell type‐specific regulation of IL‐10 expression in inflammation and disease publication-title: Immunol Res – volume: 14 start-page: 513 year: 2012 end-page: 522 article-title: Role of interplay between IL‐4 and IFN‐gamma in the in regulating M1 macrophage polarization induced by Nattectin publication-title: Int Immunopharmacol – volume: 65 start-page: 1 year: 2016 end-page: 11 article-title: Macrophage polarization: the link between inflammation and related diseases publication-title: Inflamm Res – volume: 6 start-page: a016295 year: 2014 article-title: IL‐6 in inflammation, immunity, and disease publication-title: Cold Spring Harb Perspect Biol – volume: 201 start-page: 77 year: 2018 end-page: 86 article-title: Survival of mice with gastrointestinal acute radiation syndrome through control of bacterial translocation publication-title: J Immunol – volume: 54 start-page: 1 year: 1993 end-page: 78 article-title: Interleukin‐6 in biology and medicine publication-title: Adv Immunol – volume: 25 start-page: 280 year: 2004 end-page: 288 article-title: The two NF‐kappa B activation pathways and their role in innate and adaptive immunity publication-title: Trends Immunol – volume: 9 start-page: 1175 year: 2018 article-title: Transcriptional regulation of macrophages polarization by microRNAs publication-title: Front Immunol – volume: 78 start-page: 1775 year: 2014 end-page: 1781 article-title: Macrophage phenotypes and their modulation in atherosclerosis publication-title: Circ J – volume: 122 start-page: 4190 year: 2012 end-page: 4202 article-title: MicroRNA‐155 promotes atherosclerosis by repressing Bcl6 in macrophages publication-title: J Clin Invest – volume: 20 start-page: 701 year: 2010 end-page: 712 article-title: Fra‐1 protooncogene regulates IL‐6 expression in macrophages and promotes the generation of M2d macrophages publication-title: Cell Res – volume: 7 start-page: 56 year: 2015 article-title: Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains publication-title: Alzheimers Res Ther – volume: 106 start-page: 462 year: 2012 end-page: 468 article-title: Tumor‐associated macrophages promote angiogenesis and lymphangiogenesis of gastric cancer publication-title: J Surg Oncol – volume: 13 year: 2018 article-title: Nod2 is required for antigen‐specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform publication-title: Plos One – volume: 12 year: 2017 article-title: Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival publication-title: Plos One – start-page: 131 year: 2015 end-page: 147 – volume: 65 start-page: 177 year: 2015 end-page: 188 article-title: Extracellular, but not intracellular HMGB1, facilitates self‐DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis publication-title: Mol Immunol – volume: 547 start-page: 300 year: 2014 end-page: 309 article-title: Dynamic expression of microRNAs in M2b polarized macrophages associated with systemic lupus erythematosus publication-title: Gene – volume: 14 start-page: 187 year: 2017 end-page: 195 article-title: M1 macrophages are predominantly recruited to the major pelvic ganglion of the rat following cavernous nerve injury publication-title: J Sex Med – volume: 44 start-page: 450 year: 2016 end-page: 462 article-title: Macrophages in tissue repair, regeneration, and fibrosis publication-title: Immunity – volume: 21 start-page: 508 year: 2012 end-page: 516 article-title: Production of anti‐double‐stranded DNA antibodies in activated lymphocyte derived DNA induced lupus model was dependent on CD4(+) T cells publication-title: Lupus – volume: 22 start-page: 5 year: 2015 end-page: 7 article-title: Discovery and annotation of long noncoding RNAs publication-title: Nat Struct Mol Biol – volume: 25 start-page: 677 year: 2004 end-page: 686 article-title: The chemokine system in diverse forms of macrophage activation and polarization publication-title: Trends Immunol – volume: 19 start-page: E1801 year: 2018 article-title: Role of human macrophage polarization in inflammation during infectious diseases publication-title: Int J Mol Sci – volume: 288 start-page: 35428 year: 2013 end-page: 35436 article-title: miR‐125a‐5p regulates differential activation of macrophages and inflammation publication-title: J Biol Chem – volume: 244 start-page: 75 year: 2011 end-page: 84 article-title: The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling publication-title: Immunol Rev – volume: 8 start-page: 958 year: 2008 end-page: 969 article-title: Exploring the full spectrum of macrophage activation publication-title: Nat Rev Immunol – volume: 185 start-page: 420 year: 2015 end-page: 431 article-title: M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections publication-title: Am J Pathol – volume: 279 start-page: 592 year: 2016 end-page: 605 article-title: Heat‐killed Staphylococcus aureus reduces atherosclerosis by inducing anti‐inflammatory macrophages publication-title: J Intern Med – volume: 35 start-page: 3212 year: 2015 end-page: 3224 article-title: PU.1‐regulated long noncoding RNA lnc‐MC controls human monocyte/macrophage differentiation through interaction with microRNA 199a‐5p publication-title: Mol Cell Biol – volume: 71 start-page: 619 year: 2016 ident: 2023032406362400800_jlb10302-cit-0048 article-title: Dextran sodium sulfate alters cytokine production in macrophages in vitro publication-title: Pharmazie – volume: 177 start-page: 7303 year: 2006 ident: 2023032406362400800_jlb10302-cit-0069 article-title: Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression publication-title: J Immunol doi: 10.4049/jimmunol.177.10.7303 – volume: 30 start-page: 295 year: 2012 ident: 2023032406362400800_jlb10302-cit-0095 article-title: microRNA regulation of inflammatory responses publication-title: Annu Rev Immunol doi: 10.1146/annurev-immunol-020711-075013 – volume: 6 start-page: 19705 year: 2016 ident: 2023032406362400800_jlb10302-cit-0110 article-title: Identification of differentially expressed long non-coding RNAs in polarized macrophages publication-title: Sci Rep doi: 10.1038/srep19705 – volume: 16 start-page: 448 year: 2015 ident: 2023032406362400800_jlb10302-cit-0081 article-title: IL-6 as a keystone cytokine in health and disease publication-title: Nat Immunol doi: 10.1038/ni.3153 – volume: 48 start-page: 1532 year: 2011 ident: 2023032406362400800_jlb10302-cit-0166 article-title: Blockade of TLR9 signaling in B cells impaired anti-dsDNA antibody production in mice induced by activated syngenic lymphocyte-derived DNA immunization publication-title: Mol Immunol doi: 10.1016/j.molimm.2011.04.016 – volume: 62 start-page: 1779 year: 2015 ident: 2023032406362400800_jlb10302-cit-0028 article-title: Chemokine (C-X-C motif) receptor 3-positive B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma publication-title: Hepatology doi: 10.1002/hep.28020 – volume: 1619 start-page: 1 year: 2015 ident: 2023032406362400800_jlb10302-cit-0006 article-title: Macrophage activation and its role in repair and pathology after spinal cord injury publication-title: Brain Res doi: 10.1016/j.brainres.2014.12.045 – volume: 493 start-page: 170 year: 2017 ident: 2023032406362400800_jlb10302-cit-0043 article-title: M2b macrophage polarization accompanied with reduction of long noncoding RNA GAS5 publication-title: Biochem Biophys Res Commun doi: 10.1016/j.bbrc.2017.09.053 – volume: 287 start-page: 21816 year: 2012 ident: 2023032406362400800_jlb10302-cit-0007 article-title: Identifying functional microRNAs in macrophages with polarized phenotypes publication-title: J Biol Chem doi: 10.1074/jbc.M111.327031 – start-page: 131 volume-title: Innovative Medicine: Basic Research and Development year: 2015 ident: 2023032406362400800_jlb10302-cit-0085 doi: 10.1007/978-4-431-55651-0_11 – volume: 12 start-page: 10 year: 2015 ident: 2023032406362400800_jlb10302-cit-0005 article-title: Macrophage subsets in atherosclerosis publication-title: Nat Rev Cardiol doi: 10.1038/nrcardio.2014.173 – volume: 122 start-page: 4190 year: 2012 ident: 2023032406362400800_jlb10302-cit-0100 article-title: MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages publication-title: J Clin Invest doi: 10.1172/JCI61716 – volume: 187 start-page: 1764 year: 2011 ident: 2023032406362400800_jlb10302-cit-0089 article-title: Macrophage differentiation and polarization via phosphatidylinositol 3-kinase/Akt-ERK signaling pathway conferred by serum amyloid P component publication-title: J Immunol doi: 10.4049/jimmunol.1002315 – volume: 72 start-page: 101 year: 2002 ident: 2023032406362400800_jlb10302-cit-0023 article-title: A novel phenotype for an activated macrophage: the type 2 activated macrophage publication-title: J Leukoc Biol doi: 10.1189/jlb.72.1.101 – volume: 262 start-page: 153 year: 2014 ident: 2023032406362400800_jlb10302-cit-0011 article-title: Macrophage phenotypes in atherosclerosis publication-title: Immunol Rev doi: 10.1111/imr.12218 – volume: 4 start-page: 341 year: 2012 ident: 2023032406362400800_jlb10302-cit-0099 article-title: Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155 publication-title: J Mol Cell Biol doi: 10.1093/jmcb/mjs044 – volume: 106 start-page: 14978 year: 2009 ident: 2023032406362400800_jlb10302-cit-0117 article-title: Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0809784106 – volume: 189 start-page: 296 year: 2012 ident: 2023032406362400800_jlb10302-cit-0050 article-title: Role of M2b macrophages in the acceleration of bacterial translocation and subsequent sepsis in mice exposed to whole body [137Cs] gamma-irradiation publication-title: J Immunol doi: 10.4049/jimmunol.1200350 – volume: 97 start-page: 1715 year: 1996 ident: 2023032406362400800_jlb10302-cit-0115 article-title: Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion publication-title: J Clin Invest doi: 10.1172/JCI118598 – volume: 11 start-page: 2428 year: 2017 ident: 2023032406362400800_jlb10302-cit-0140 article-title: Phenotype determines nanoparticle uptake by human macrophages from liver and blood publication-title: ACS Nano doi: 10.1021/acsnano.6b06245 – volume: 73 start-page: 8 year: 2015 ident: 2023032406362400800_jlb10302-cit-0141 article-title: Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype publication-title: Cytokine doi: 10.1016/j.cyto.2015.01.017 – volume: 17 start-page: 395 year: 2018 ident: 2023032406362400800_jlb10302-cit-0083 article-title: Interleukin-6: designing specific therapeutics for a complex cytokine publication-title: Nat Rev Drug Discov doi: 10.1038/nrd.2018.45 – volume: 3 start-page: 745 year: 2003 ident: 2023032406362400800_jlb10302-cit-0073 article-title: Signalling pathways of the TNF superfamily: a double-edged sword publication-title: Nat Rev Immunol doi: 10.1038/nri1184 – volume: 43 start-page: 904 year: 2011 ident: 2023032406362400800_jlb10302-cit-0106 article-title: Molecular mechanisms of long noncoding RNAs publication-title: Mol Cell doi: 10.1016/j.molcel.2011.08.018 – volume: 186 start-page: 165 year: 1997 ident: 2023032406362400800_jlb10302-cit-0037 article-title: Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309 publication-title: J Exp Med doi: 10.1084/jem.186.1.165 – volume: 99 start-page: 505 year: 2013 ident: 2023032406362400800_jlb10302-cit-0068 article-title: Factor-Xa-induced mitogenesis and migration require sphingosine kinase activity and S1P formation in human vascular smooth muscle cells publication-title: Cardiovasc Res doi: 10.1093/cvr/cvt112 – volume: 110 start-page: 455 year: 2014 ident: 2023032406362400800_jlb10302-cit-0132 article-title: Irradiation of existing atherosclerotic lesions increased inflammation by favoring pro-inflammatory macrophages publication-title: Radiother Oncol doi: 10.1016/j.radonc.2014.01.006 – volume: 201 start-page: 77 year: 2018 ident: 2023032406362400800_jlb10302-cit-0049 article-title: Survival of mice with gastrointestinal acute radiation syndrome through control of bacterial translocation publication-title: J Immunol doi: 10.4049/jimmunol.1701515 – volume: 22 start-page: 153 year: 2001 ident: 2023032406362400800_jlb10302-cit-0119 article-title: Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions publication-title: Endocr Rev – volume: 11 start-page: 3559 year: 2012 ident: 2023032406362400800_jlb10302-cit-0123 article-title: Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K publication-title: Cell Cycle doi: 10.4161/cc.21572 – volume: 117 start-page: 7 year: 2017 ident: 2023032406362400800_jlb10302-cit-0063 article-title: Pathophysiological relevance of macrophage subsets in atherogenesis publication-title: Thromb Haemost doi: 10.1160/TH16-08-0593 – volume: 223 start-page: 383 year: 2018 ident: 2023032406362400800_jlb10302-cit-0010 article-title: Macrophages: their role, activation and polarization in pulmonary diseases publication-title: Immunobiology doi: 10.1016/j.imbio.2017.11.001 – volume: 8 start-page: e60086 year: 2013 ident: 2023032406362400800_jlb10302-cit-0047 article-title: Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers publication-title: Plos One doi: 10.1371/journal.pone.0060086 – volume: 245 start-page: 228 year: 2017 ident: 2023032406362400800_jlb10302-cit-0024 article-title: M2b macrophages reduce early reperfusion injury after myocardial ischemia in mice: a predominant role of inhibiting apoptosis via A20 publication-title: Int J Cardiol doi: 10.1016/j.ijcard.2017.07.085 – volume: 152 start-page: 10 year: 2014 ident: 2023032406362400800_jlb10302-cit-0075 article-title: Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization publication-title: Clin Immunol doi: 10.1016/j.clim.2014.02.016 – volume: 547 start-page: 300 year: 2014 ident: 2023032406362400800_jlb10302-cit-0078 article-title: Dynamic expression of microRNAs in M2b polarized macrophages associated with systemic lupus erythematosus publication-title: Gene doi: 10.1016/j.gene.2014.06.065 – volume: 5 start-page: e111 year: 2016 ident: 2023032406362400800_jlb10302-cit-0164 article-title: Guanylate-binding protein 5 is a marker of interferon-gamma-induced classically activated macrophages publication-title: Clin Transl Immunology doi: 10.1038/cti.2016.59 – volume: 14 start-page: 513 year: 2012 ident: 2023032406362400800_jlb10302-cit-0057 article-title: Role of interplay between IL-4 and IFN-gamma in the in regulating M1 macrophage polarization induced by Nattectin publication-title: Int Immunopharmacol doi: 10.1016/j.intimp.2012.08.009 – volume: 80 start-page: 342 year: 2006 ident: 2023032406362400800_jlb10302-cit-0039 article-title: Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2) publication-title: J Leukoc Biol doi: 10.1189/jlb.1005586 – volume: 152 start-page: 4929 year: 1994 ident: 2023032406362400800_jlb10302-cit-0052 article-title: Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule publication-title: J Immunol doi: 10.4049/jimmunol.152.10.4929 – volume: 13 start-page: e0196950 year: 2018 ident: 2023032406362400800_jlb10302-cit-0091 article-title: Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform publication-title: Plos One doi: 10.1371/journal.pone.0196950 – volume: 26 start-page: 2450 year: 2015 ident: 2023032406362400800_jlb10302-cit-0021 article-title: Variations in genes regulating tumor-associated macrophages (TAMs) to predict outcomes of bevacizumab-based treatment in patients with metastatic colorectal cancer: results from TRIBE and FIRE3 trials publication-title: Ann Oncol doi: 10.1093/annonc/mdv474 – volume: 1842 start-page: 446 year: 2014 ident: 2023032406362400800_jlb10302-cit-0149 article-title: Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance publication-title: Biochim Biophys Acta doi: 10.1016/j.bbadis.2013.05.017 – volume: 19 start-page: 285 year: 2008 ident: 2023032406362400800_jlb10302-cit-0046 article-title: Targeting tumors with LIGHT to generate metastasis-clearing immunity publication-title: Cytokine Growth Factor Rev doi: 10.1016/j.cytogfr.2008.04.004 – volume: 62 start-page: 93 year: 2016 ident: 2023032406362400800_jlb10302-cit-0064 article-title: Sphingosine 1-phosphate and sphingosine kinases in health and disease: recent advances publication-title: Prog Lipid Res doi: 10.1016/j.plipres.2016.03.001 – volume: 20 start-page: 282 year: 2002 ident: 2023032406362400800_jlb10302-cit-0130 article-title: Increased risk of ischemic stroke after radiotherapy on the neck in patients younger than 60 years publication-title: J Clin Oncol doi: 10.1200/JCO.2002.20.1.282 – volume: 195 start-page: 5169 year: 2015 ident: 2023032406362400800_jlb10302-cit-0029 article-title: M2b monocytes provoke bacterial pneumonia and gut bacteria-associated sepsis in alcoholics publication-title: J Immunol doi: 10.4049/jimmunol.1501369 – volume: 32 start-page: 524 year: 2018 ident: 2023032406362400800_jlb10302-cit-0154 article-title: Epigenetic modulation of macrophage polarization- perspectives in diabetic wounds publication-title: J Diabetes Complications doi: 10.1016/j.jdiacomp.2018.01.015 – volume: 5 start-page: e12828 year: 2010 ident: 2023032406362400800_jlb10302-cit-0031 article-title: PPARgamma ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination publication-title: Plos One doi: 10.1371/journal.pone.0012828 – volume: 198 start-page: 1006 year: 2017 ident: 2023032406362400800_jlb10302-cit-0120 article-title: Akt signaling pathway in macrophage activation and M1/M2 polarization publication-title: J Immunol doi: 10.4049/jimmunol.1601515 – volume: 209 start-page: 378 year: 2008 ident: 2023032406362400800_jlb10302-cit-0144 article-title: Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury publication-title: Exp Neurol doi: 10.1016/j.expneurol.2007.06.009 – volume: 78 start-page: 1775 year: 2014 ident: 2023032406362400800_jlb10302-cit-0012 article-title: Macrophage phenotypes and their modulation in atherosclerosis publication-title: Circ J doi: 10.1253/circj.CJ-14-0621 – volume: 10 start-page: e0130713 year: 2015 ident: 2023032406362400800_jlb10302-cit-0077 article-title: Neisseria gonorrhoeae modulates immunity by polarizing human macrophages to a M2 profile publication-title: Plos One doi: 10.1371/journal.pone.0130713 – volume: 20 start-page: 701 year: 2010 ident: 2023032406362400800_jlb10302-cit-0018 article-title: Fra-1 protooncogene regulates IL-6 expression in macrophages and promotes the generation of M2d macrophages publication-title: Cell Res doi: 10.1038/cr.2010.52 – volume: 33 start-page: 699 year: 2010 ident: 2023032406362400800_jlb10302-cit-0156 article-title: STAT6 transcription factor is a facilitator of the nuclear receptor PPAR gamma-regulated gene expression in macrophages and dendritic cells publication-title: Immunity doi: 10.1016/j.immuni.2010.11.009 – volume: 167 start-page: 6453 year: 2001 ident: 2023032406362400800_jlb10302-cit-0133 article-title: IFN-alpha beta-dependent, IFN-gamma secretion by bone marrow-derived macrophages controls an intracellular bacterial infection publication-title: J Immunol doi: 10.4049/jimmunol.167.11.6453 – volume: 2015 start-page: 851252 year: 2015 ident: 2023032406362400800_jlb10302-cit-0062 article-title: Macrophage heterogeneity and plasticity: impact of macrophage biomarkers on atherosclerosis publication-title: Scientifica (Cairo) – volume: 26 start-page: 475 year: 2015 ident: 2023032406362400800_jlb10302-cit-0082 article-title: Interleukin-6: biology, signaling and strategies of blockade publication-title: Cytokine Growth Factor Rev doi: 10.1016/j.cytogfr.2015.07.004 – volume: 6 start-page: e1299301 year: 2017 ident: 2023032406362400800_jlb10302-cit-0025 article-title: Host antitumor resistance improved by the macrophage polarization in a chimera model of patients with HCC publication-title: Oncoimmunology doi: 10.1080/2162402X.2017.1299301 – volume: 14 start-page: 187 year: 2017 ident: 2023032406362400800_jlb10302-cit-0055 article-title: M1 macrophages are predominantly recruited to the major pelvic ganglion of the rat following cavernous nerve injury publication-title: J Sex Med doi: 10.1016/j.jsxm.2016.12.012 – volume: 68 start-page: 1070 year: 2018 ident: 2023032406362400800_jlb10302-cit-0066 article-title: Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2 publication-title: Hepatology doi: 10.1002/hep.29885 – volume: 112 start-page: 1796 year: 2003 ident: 2023032406362400800_jlb10302-cit-0151 article-title: Obesity is associated with macrophage accumulation in adipose tissue publication-title: J Clin Invest doi: 10.1172/JCI200319246 – volume: 208 start-page: 484 year: 1988 ident: 2023032406362400800_jlb10302-cit-0169 article-title: Effect of propranolol administration on hemodynamic and metabolic responses of burned pediatric patients publication-title: Ann Surg doi: 10.1097/00000658-198810000-00010 – volume: 6 start-page: 1182 year: 2016 ident: 2023032406362400800_jlb10302-cit-0163 article-title: Polarization of tissue-resident TFH-like cells in human hepatoma bridges innate monocyte inflammation and M2b macrophage polarization publication-title: Cancer Discov doi: 10.1158/2159-8290.CD-16-0329 – volume: 92 start-page: 477 year: 2009 ident: 2023032406362400800_jlb10302-cit-0131 article-title: Novel insights into pathological changes in muscular arteries of radiotherapy patients publication-title: Radiother Oncol doi: 10.1016/j.radonc.2009.05.021 – volume: 139 start-page: 3126 year: 1987 ident: 2023032406362400800_jlb10302-cit-0035 article-title: Cloning and characterization of a novel T cell activation gene publication-title: J Immunol doi: 10.4049/jimmunol.139.9.3126 – volume: 65 start-page: 1 year: 2016 ident: 2023032406362400800_jlb10302-cit-0009 article-title: Macrophage polarization: the link between inflammation and related diseases publication-title: Inflamm Res doi: 10.1007/s00011-015-0874-1 – volume: 13 start-page: 227 year: 2013 ident: 2023032406362400800_jlb10302-cit-0053 article-title: Molecular mechanisms of T cell co-stimulation and co-inhibition publication-title: Nat Rev Immunol doi: 10.1038/nri3405 – volume: 8 start-page: e62465 year: 2013 ident: 2023032406362400800_jlb10302-cit-0088 article-title: Mannose-binding lectin blunts macrophage polarization and ameliorates lupus nephritis publication-title: Plos One doi: 10.1371/journal.pone.0062465 – volume: 9 start-page: 59 year: 2005 ident: 2023032406362400800_jlb10302-cit-0121 article-title: The activation of Akt/PKB signaling pathway and cell survival publication-title: J Cell Mol Med doi: 10.1111/j.1582-4934.2005.tb00337.x – volume: 6 start-page: 25295 year: 2015 ident: 2023032406362400800_jlb10302-cit-0160 article-title: Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and beta2 integrin interactions publication-title: Oncotarget doi: 10.18632/oncotarget.4716 – volume: 9 start-page: 1175 year: 2018 ident: 2023032406362400800_jlb10302-cit-0161 article-title: Transcriptional regulation of macrophages polarization by microRNAs publication-title: Front Immunol doi: 10.3389/fimmu.2018.01175 – volume: 5 start-page: 3494 year: 2014 ident: 2023032406362400800_jlb10302-cit-0129 article-title: Ionizing irradiation induces acute haematopoietic syndrome and gastrointestinal syndrome independently in mice publication-title: Nat Commun doi: 10.1038/ncomms4494 – volume: 7 start-page: 56 year: 2015 ident: 2023032406362400800_jlb10302-cit-0092 article-title: Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains publication-title: Alzheimers Res Ther doi: 10.1186/s13195-015-0139-9 – volume: 7 start-page: e35994 year: 2012 ident: 2023032406362400800_jlb10302-cit-0014 article-title: Soluble immune complexes shift the TLR-induced cytokine production of distinct polarized human macrophage subsets towards IL-10 publication-title: Plos One doi: 10.1371/journal.pone.0035994 – volume: 30 start-page: 3887 year: 2011 ident: 2023032406362400800_jlb10302-cit-0162 article-title: Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2 publication-title: Oncogene doi: 10.1038/onc.2011.112 – volume: 41 start-page: 1733 year: 2011 ident: 2023032406362400800_jlb10302-cit-0124 article-title: Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: implications for NO synthase 2 expression publication-title: Eur J Immunol doi: 10.1002/eji.201041101 – volume: 179 start-page: 8525 year: 2007 ident: 2023032406362400800_jlb10302-cit-0170 article-title: Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling publication-title: J Immunol doi: 10.4049/jimmunol.179.12.8525 – volume: 233 start-page: 6425 year: 2018 ident: 2023032406362400800_jlb10302-cit-0008 article-title: Macrophage plasticity, polarization, and function in health and disease publication-title: J Cell Physiol doi: 10.1002/jcp.26429 – volume: 189 start-page: 3508 year: 2012 ident: 2023032406362400800_jlb10302-cit-0016 article-title: Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction publication-title: J Immunol doi: 10.4049/jimmunol.1200662 – volume: 9 start-page: 101 year: 2016 ident: 2023032406362400800_jlb10302-cit-0042 article-title: Update on the role of alternatively activated macrophages in asthma publication-title: J Asthma Allergy doi: 10.2147/JAA.S104508 – volume: 87 start-page: 223 year: 2010 ident: 2023032406362400800_jlb10302-cit-0051 article-title: HVEM/LIGHT/BTLA/CD160 cosignaling pathways as targets for immune regulation publication-title: J Leukoc Biol doi: 10.1189/jlb.0809590 – volume: 289 start-page: 28433 year: 2014 ident: 2023032406362400800_jlb10302-cit-0105 article-title: Regulation of activation-associated microRNA accumulation rates during monocyte-to-macrophage differentiation publication-title: J Biol Chem doi: 10.1074/jbc.M114.599316 – volume: 117 start-page: 175 year: 2007 ident: 2023032406362400800_jlb10302-cit-0152 article-title: Obesity induces a phenotypic switch in adipose tissue macrophage polarization publication-title: J Clin Invest doi: 10.1172/JCI29881 – volume: 22 start-page: 5 year: 2015 ident: 2023032406362400800_jlb10302-cit-0107 article-title: Discovery and annotation of long noncoding RNAs publication-title: Nat Struct Mol Biol doi: 10.1038/nsmb.2942 – volume: 110 start-page: 4319 year: 2007 ident: 2023032406362400800_jlb10302-cit-0017 article-title: Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells publication-title: Blood doi: 10.1182/blood-2007-02-072587 – volume: 3 start-page: 128 year: 2009 ident: 2023032406362400800_jlb10302-cit-0054 article-title: Dynamics of CD86 expression on allergic inflammation–new insights publication-title: Recent Pat Inflamm Allergy Drug Discov doi: 10.2174/187221309788489751 – volume: 119 start-page: 2951 year: 2018 ident: 2023032406362400800_jlb10302-cit-0111 article-title: Long non-coding RNA cox-2 prevents immune evasion and metastasis of hepatocellular carcinoma by altering M1/M2 macrophage polarization publication-title: J Cell Biochem doi: 10.1002/jcb.26509 – volume: 180 start-page: 6270 year: 2008 ident: 2023032406362400800_jlb10302-cit-0056 article-title: Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo publication-title: J Immunol doi: 10.4049/jimmunol.180.9.6270 – volume: 63 start-page: 4249 year: 2014 ident: 2023032406362400800_jlb10302-cit-0109 article-title: Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA publication-title: Diabetes doi: 10.2337/db14-0298 – volume: 17 start-page: 2 year: 2016 ident: 2023032406362400800_jlb10302-cit-0003 article-title: The development and maintenance of resident macrophages publication-title: Nat Immunol doi: 10.1038/ni.3341 – volume: 80 start-page: 1298 year: 2006 ident: 2023032406362400800_jlb10302-cit-0034 article-title: Biochemical and functional characterization of three activated macrophage populations publication-title: J Leukoc Biol doi: 10.1189/jlb.0406249 – volume: 92 start-page: 859 year: 2012 ident: 2023032406362400800_jlb10302-cit-0040 article-title: CCL1 released from M2b macrophages is essentially required for the maintenance of their properties publication-title: J Leukoc Biol doi: 10.1189/jlb.0212107 – volume: 265 start-page: 621 year: 1990 ident: 2023032406362400800_jlb10302-cit-0086 article-title: Interleukin-6 and the acute phase response publication-title: Biochem J doi: 10.1042/bj2650621 – volume: 68 start-page: 2300 year: 2016 ident: 2023032406362400800_jlb10302-cit-0090 article-title: Monocyte microRNA expression in active systemic juvenile idiopathic arthritis implicates microRNA-125a-5p in polarized monocyte phenotypes publication-title: Arthritis Rheumatol doi: 10.1002/art.39694 – volume: 2 start-page: 33 year: 2011 ident: 2023032406362400800_jlb10302-cit-0038 article-title: The human cutaneous chemokine system publication-title: Front Immunol doi: 10.3389/fimmu.2011.00033 – volume: 198 start-page: 2589 year: 2017 ident: 2023032406362400800_jlb10302-cit-0093 article-title: Dependence of glomerulonephritis induction on novel intraglomerular alternatively activated bone marrow-derived macrophages and Mac-1 and PD-L1 in lupus-prone NZM2328 mice publication-title: J Immunol doi: 10.4049/jimmunol.1601565 – volume: 143 start-page: 2907 year: 1989 ident: 2023032406362400800_jlb10302-cit-0036 article-title: A novel polypeptide secreted by activated human T lymphocytes publication-title: J Immunol doi: 10.4049/jimmunol.143.9.2907 – volume: 10 start-page: 899 year: 2018 ident: 2023032406362400800_jlb10302-cit-0157 article-title: Dual role of macrophage in tumor immunity publication-title: Immunotherapy doi: 10.2217/imt-2018-0006 – volume: 2013 start-page: 264124 year: 2013 ident: 2023032406362400800_jlb10302-cit-0159 article-title: Microglia and macrophages in malignant gliomas: recent discoveries and implications for promising therapies publication-title: Clin Dev Immunol – volume: 106 start-page: 462 year: 2012 ident: 2023032406362400800_jlb10302-cit-0022 article-title: Tumor-associated macrophages promote angiogenesis and lymphangiogenesis of gastric cancer publication-title: J Surg Oncol doi: 10.1002/jso.23110 – volume: 185 start-page: 420 year: 2015 ident: 2023032406362400800_jlb10302-cit-0135 article-title: M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections publication-title: Am J Pathol doi: 10.1016/j.ajpath.2014.09.022 – volume: 8 start-page: 958 year: 2008 ident: 2023032406362400800_jlb10302-cit-0002 article-title: Exploring the full spectrum of macrophage activation publication-title: Nat Rev Immunol doi: 10.1038/nri2448 – volume: 35 start-page: 3212 year: 2015 ident: 2023032406362400800_jlb10302-cit-0108 article-title: PU.1-regulated long noncoding RNA lnc-MC controls human monocyte/macrophage differentiation through interaction with microRNA 199a-5p publication-title: Mol Cell Biol doi: 10.1128/MCB.00429-15 – volume: 185 start-page: 2044 year: 2010 ident: 2023032406362400800_jlb10302-cit-0139 article-title: Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages publication-title: J Immunol doi: 10.4049/jimmunol.1000017 – volume: 180 start-page: 1938 year: 2008 ident: 2023032406362400800_jlb10302-cit-0142 article-title: Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis publication-title: J Immunol doi: 10.4049/jimmunol.180.3.1938 – volume: 162 start-page: 79 year: 2018 ident: 2023032406362400800_jlb10302-cit-0150 article-title: M1/M2 macrophage polarization in human obese adipose tissue publication-title: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub doi: 10.5507/bp.2018.015 – volume: 19 start-page: E1801 year: 2018 ident: 2023032406362400800_jlb10302-cit-0020 article-title: Role of human macrophage polarization in inflammation during infectious diseases publication-title: Int J Mol Sci doi: 10.3390/ijms19061801 – volume: 11 start-page: 936 year: 2010 ident: 2023032406362400800_jlb10302-cit-0128 article-title: The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection publication-title: Nat Immunol doi: 10.1038/ni.1920 – volume: 6 start-page: a016295 year: 2014 ident: 2023032406362400800_jlb10302-cit-0084 article-title: IL-6 in inflammation, immunity, and disease publication-title: Cold Spring Harb Perspect Biol doi: 10.1101/cshperspect.a016295 – volume: 12 start-page: e0182075 year: 2017 ident: 2023032406362400800_jlb10302-cit-0067 article-title: Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival publication-title: Plos One doi: 10.1371/journal.pone.0182075 – volume: 9 start-page: 444 year: 2018 ident: 2023032406362400800_jlb10302-cit-0072 article-title: Tumor necrosis factor alpha and regulatory T cells in oncoimmunology publication-title: Front Immunol doi: 10.3389/fimmu.2018.00444 – volume: 104 start-page: 487 year: 2001 ident: 2023032406362400800_jlb10302-cit-0074 article-title: The TNF and TNF receptor superfamilies: integrating mammalian biology publication-title: Cell doi: 10.1016/S0092-8674(01)00237-9 – volume: 40 start-page: 1162 year: 2010 ident: 2023032406362400800_jlb10302-cit-0065 article-title: CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1 publication-title: Eur J Immunol doi: 10.1002/eji.200939703 – volume: 7 start-page: e2261 year: 2016 ident: 2023032406362400800_jlb10302-cit-0101 article-title: MicroRNA-155 facilitates skeletal muscle regeneration by balancing pro- and anti-inflammatory macrophages publication-title: Cell Death Dis doi: 10.1038/cddis.2016.165 – volume: 244 start-page: 75 year: 2011 ident: 2023032406362400800_jlb10302-cit-0045 article-title: The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling publication-title: Immunol Rev doi: 10.1111/j.1600-065X.2011.01061.x – volume: 103 start-page: 12481 year: 2006 ident: 2023032406362400800_jlb10302-cit-0098 article-title: NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0605298103 – volume: 187 start-page: 1998 year: 2017 ident: 2023032406362400800_jlb10302-cit-0138 article-title: Short-term alcohol abstinence improves antibacterial defenses of chronic alcohol-consuming mice against gut bacteria-associated sepsis caused by enterococcus faecalis oral infection publication-title: Am J Pathol doi: 10.1016/j.ajpath.2017.05.013 – volume: 13 start-page: 27 year: 2016 ident: 2023032406362400800_jlb10302-cit-0113 article-title: Long non-coding RNA-GAS5 acts as a tumor suppressor in bladder transitional cell carcinoma via regulation of chemokine (C-C motif) ligand 1 expression publication-title: Mol Med Rep doi: 10.3892/mmr.2015.4503 – volume: 288 start-page: 35428 year: 2013 ident: 2023032406362400800_jlb10302-cit-0104 article-title: miR-125a-5p regulates differential activation of macrophages and inflammation publication-title: J Biol Chem doi: 10.1074/jbc.M112.426866 – volume: 8 start-page: e65542 year: 2013 ident: 2023032406362400800_jlb10302-cit-0079 article-title: Granulin exacerbates lupus nephritis via enhancing macrophage M2b polarization publication-title: Plos One doi: 10.1371/journal.pone.0065542 – volume: 9 start-page: e104506 year: 2014 ident: 2023032406362400800_jlb10302-cit-0125 article-title: PI3K/Akt signaling pathway modulates influenza virus induced mouse alveolar macrophage polarization to M1/M2b publication-title: Plos One doi: 10.1371/journal.pone.0104506 – volume: 184 start-page: 6465 year: 2010 ident: 2023032406362400800_jlb10302-cit-0118 article-title: Blockade of Notch1 signaling alleviates murine lupus via blunting macrophage activation and M2b polarization publication-title: J Immunol doi: 10.4049/jimmunol.0904016 – volume: 1 start-page: 10 year: 2012 ident: 2023032406362400800_jlb10302-cit-0019 article-title: Regulation of macrophage polarization and wound healing publication-title: Adv Wound Care (New Rochelle) doi: 10.1089/wound.2011.0307 – volume: 31 start-page: 797 year: 2013 ident: 2023032406362400800_jlb10302-cit-0097 article-title: Expression profiles of miRNAs in polarized macrophages publication-title: Int J Mol Med doi: 10.3892/ijmm.2013.1260 – volume: 36 start-page: 2468 year: 2015 ident: 2023032406362400800_jlb10302-cit-0148 article-title: Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2015.05.016 – volume: 54 start-page: 1 year: 1993 ident: 2023032406362400800_jlb10302-cit-0087 article-title: Interleukin-6 in biology and medicine publication-title: Adv Immunol doi: 10.1016/S0065-2776(08)60532-5 – volume: 33 start-page: 9684 year: 2013 ident: 2023032406362400800_jlb10302-cit-0070 article-title: Intracranial injection of Gammagard, a human IVIg, modulates the inflammatory response of the brain and lowers Abeta in APP/PS1 mice along a different time course than anti-Abeta antibodies publication-title: J Neurosci doi: 10.1523/JNEUROSCI.1220-13.2013 – volume: 44 start-page: 450 year: 2016 ident: 2023032406362400800_jlb10302-cit-0013 article-title: Macrophages in tissue repair, regeneration, and fibrosis publication-title: Immunity doi: 10.1016/j.immuni.2016.02.015 – volume: 8 start-page: 1214 year: 2017 ident: 2023032406362400800_jlb10302-cit-0060 article-title: Cannabinoid receptor 1 participates in liver inflammation by promoting M1 macrophage polarization via RhoA/NF-kappaB p65 and ERK1/2 pathways, respectively, in mouse liver fibrogenesis publication-title: Front Immunol doi: 10.3389/fimmu.2017.01214 – volume: 219 start-page: 737 year: 2014 ident: 2023032406362400800_jlb10302-cit-0061 article-title: Spleen-derived macrophages are readily polarized into classically activated (M1) or alternatively activated (M2) states publication-title: Immunobiology doi: 10.1016/j.imbio.2014.05.005 – volume: 6 start-page: 171 year: 2014 ident: 2023032406362400800_jlb10302-cit-0158 article-title: Proinflammatory-activated glioma cells induce a switch in microglial polarization and activation status, from a predominant M2b phenotype to a mixture of M1 and M2a/B polarized cells publication-title: ASN Neuro doi: 10.1042/AN20130045 – volume: 55 start-page: 35 year: 2016 ident: 2023032406362400800_jlb10302-cit-0155 article-title: Peroxisome proliferator-activated receptor gamma regulates chronic alcohol-induced alveolar macrophage dysfunction publication-title: Am J Respir Cell Mol Biol doi: 10.1165/rcmb.2015-0077OC – volume: 65 start-page: 177 year: 2015 ident: 2023032406362400800_jlb10302-cit-0165 article-title: Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis publication-title: Mol Immunol doi: 10.1016/j.molimm.2015.01.023 – volume: 8 start-page: 21 year: 1998 ident: 2023032406362400800_jlb10302-cit-0044 article-title: LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator publication-title: Immunity doi: 10.1016/S1074-7613(00)80455-0 – volume: 24 start-page: 1181 year: 2018 ident: 2023032406362400800_jlb10302-cit-0143 article-title: Functional macrophages and gastrointestinal disorders publication-title: World J Gastroenterol doi: 10.3748/wjg.v24.i11.1181 – volume: 10 start-page: 520 year: 2014 ident: 2023032406362400800_jlb10302-cit-0127 article-title: Macrophage polarization in inflammatory diseases publication-title: Int J Biol Sci doi: 10.7150/ijbs.8879 – volume: 136 start-page: 215 year: 2009 ident: 2023032406362400800_jlb10302-cit-0096 article-title: MicroRNAs: target recognition and regulatory functions publication-title: Cell doi: 10.1016/j.cell.2009.01.002 – volume: 4 start-page: 385 year: 2003 ident: 2023032406362400800_jlb10302-cit-0134 article-title: Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens publication-title: Nat Rev Mol Cell Biol doi: 10.1038/nrm1104 – volume: 39 start-page: 1704 year: 2016 ident: 2023032406362400800_jlb10302-cit-0059 article-title: Nanoparticle-delivered IRF5 siRNA facilitates M1 to M2 transition, reduces demyelination and neurofilament loss, and promotes functional recovery after spinal cord injury in mice publication-title: Inflammation doi: 10.1007/s10753-016-0405-4 – volume: 110 start-page: 1617 year: 2009 ident: 2023032406362400800_jlb10302-cit-0145 article-title: Interleukin-10 provides direct trophic support to neurons publication-title: J Neurochem doi: 10.1111/j.1471-4159.2009.06263.x – volume: 13 start-page: 151 year: 2012 ident: 2023032406362400800_jlb10302-cit-0041 article-title: Macrophage subpopulations in systemic lupus erythematosus publication-title: Discov Med – volume: 18 start-page: 1801 year: 2017 ident: 2023032406362400800_jlb10302-cit-0112 article-title: LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination publication-title: EMBO Rep doi: 10.15252/embr.201643668 – volume: 20 start-page: 377 year: 2014 ident: 2023032406362400800_jlb10302-cit-0153 article-title: Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity publication-title: Nat Med doi: 10.1038/nm.3467 – volume: 95 start-page: 198 year: 2017 ident: 2023032406362400800_jlb10302-cit-0026 article-title: Macrophage polarization and MRSA infection in burned mice publication-title: Immunol Cell Biol doi: 10.1038/icb.2016.84 – volume: 7 start-page: 1291 year: 2001 ident: 2023032406362400800_jlb10302-cit-0114 article-title: Possible new role for NF-kappaB in the resolution of inflammation publication-title: Nat Med doi: 10.1038/nm1201-1291 – volume: 273 start-page: 83 year: 2015 ident: 2023032406362400800_jlb10302-cit-0032 article-title: Age decreases macrophage IL-10 expression: implications for functional recovery and tissue repair in spinal cord injury publication-title: Exp Neurol doi: 10.1016/j.expneurol.2015.08.001 – volume: 125 start-page: 2892 year: 2012 ident: 2023032406362400800_jlb10302-cit-0102 article-title: A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation publication-title: Circulation doi: 10.1161/CIRCULATIONAHA.111.087817 – volume: 12 start-page: 231 year: 2011 ident: 2023032406362400800_jlb10302-cit-0126 article-title: IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses publication-title: Nat Immunol doi: 10.1038/ni.1990 – volume: 13 start-page: 453 year: 2008 ident: 2023032406362400800_jlb10302-cit-0001 article-title: Macrophage activation and polarization publication-title: Front Biosci doi: 10.2741/2692 – volume: 47 start-page: 185 year: 2010 ident: 2023032406362400800_jlb10302-cit-0033 article-title: Cell type-specific regulation of IL-10 expression in inflammation and disease publication-title: Immunol Res doi: 10.1007/s12026-009-8150-5 – volume: 279 start-page: 592 year: 2016 ident: 2023032406362400800_jlb10302-cit-0076 article-title: Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages publication-title: J Intern Med doi: 10.1111/joim.12484 – volume: 26 start-page: 269 year: 2016 ident: 2023032406362400800_jlb10302-cit-0027 article-title: The polarization of M2b monocytes in cultures of burn patient peripheral CD14(+) cells treated with a selected human CCL1 antisense oligodeoxynucleotide publication-title: Nucleic Acid Ther doi: 10.1089/nat.2016.0617 – volume: 21 start-page: 508 year: 2012 ident: 2023032406362400800_jlb10302-cit-0168 article-title: Production of anti-double-stranded DNA antibodies in activated lymphocyte derived DNA induced lupus model was dependent on CD4(+) T cells publication-title: Lupus doi: 10.1177/0961203311434940 – volume: 25 start-page: 280 year: 2004 ident: 2023032406362400800_jlb10302-cit-0116 article-title: The two NF-kappa B activation pathways and their role in innate and adaptive immunity publication-title: Trends Immunol doi: 10.1016/j.it.2004.03.008 – volume: 38 start-page: 1038 year: 2013 ident: 2023032406362400800_jlb10302-cit-0030 article-title: The C-type lectin receptors dectin-1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum publication-title: Immunity doi: 10.1016/j.immuni.2013.04.010 – volume: 30 start-page: 1311 year: 2013 ident: 2023032406362400800_jlb10302-cit-0146 article-title: The therapeutic role of interleukin-10 after spinal cord injury publication-title: J Neurotrauma doi: 10.1089/neu.2012.2651 – volume: 185 start-page: 7174 year: 2010 ident: 2023032406362400800_jlb10302-cit-0137 article-title: M2b monocytes predominated in peripheral blood of severely burned patients publication-title: J Immunol doi: 10.4049/jimmunol.0903935 – volume: 77 start-page: 205 year: 2016 ident: 2023032406362400800_jlb10302-cit-0058 article-title: MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA publication-title: Mol Immunol doi: 10.1016/j.molimm.2016.08.007 – volume: 44 start-page: 1108 year: 2005 ident: 2023032406362400800_jlb10302-cit-0167 article-title: Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/keh656 – volume: 13 start-page: 183 year: 2014 ident: 2023032406362400800_jlb10302-cit-0147 article-title: Neuroinflammatory phenotypes and their roles in Alzheimer's disease publication-title: Neurodegener Dis doi: 10.1159/000354228 – volume: 290 start-page: 28286 year: 2015 ident: 2023032406362400800_jlb10302-cit-0103 article-title: Long non-coding RNA growth arrest-specific transcript 5 (GAS5) inhibits liver fibrogenesis through a mechanism of competing endogenous RNA publication-title: J Biol Chem doi: 10.1074/jbc.M115.683813 – volume: 89 start-page: 797 year: 2011 ident: 2023032406362400800_jlb10302-cit-0136 article-title: Propranolol as a modulator of M2b monocytes in severely burned patients publication-title: J Leukoc Biol doi: 10.1189/jlb.1010553 – volume: 25 start-page: 677 year: 2004 ident: 2023032406362400800_jlb10302-cit-0004 article-title: The chemokine system in diverse forms of macrophage activation and polarization publication-title: Trends Immunol doi: 10.1016/j.it.2004.09.015 – volume: 2015 start-page: 816460 year: 2015 ident: 2023032406362400800_jlb10302-cit-0015 article-title: Understanding the mysterious M2 macrophage through activation markers and effector mechanisms publication-title: Mediators Inflamm doi: 10.1155/2015/816460 – volume: 2012 start-page: 495243 year: 2012 ident: 2023032406362400800_jlb10302-cit-0071 article-title: A changing perspective on the role of neuroinflammation in Alzheimer's disease publication-title: Int J Alzheimers Dis – volume: 288 start-page: 13534 year: 2013 ident: 2023032406362400800_jlb10302-cit-0080 article-title: DNA-dependent activator of interferon-regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway publication-title: J Biol Chem doi: 10.1074/jbc.M113.457218 – volume: 24 start-page: 358 year: 2003 ident: 2023032406362400800_jlb10302-cit-0122 article-title: PI3K and negative regulation of TLR signaling publication-title: Trends Immunol doi: 10.1016/S1471-4906(03)00139-X – volume: 136 start-page: 26 year: 2009 ident: 2023032406362400800_jlb10302-cit-0094 article-title: MicroRNA control in the immune system: basic principles publication-title: Cell doi: 10.1016/j.cell.2008.12.027 |
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