Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer

Serum from one hundred and ten breast cancer patients and thirty healthy female volunteers, were prospectively collected and evaluated for serum levels of Shh and IL-6 using human Shh and IL-6 specific enzyme-linked immunoassays. All patients were regularly monitored for event free survival (EFS) an...

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Bibliographic Details
Published in:	Scientific reports Vol. 7; no. 1; pp. 1796 - 12
Main Authors:	Noman, A. S., Uddin, M., Chowdhury, A. A., Nayeem, M. J., Raihan, Z., Rashid, M. I., Azad, A. K., Rahman, M. L., Barua, D., Sultana, A., Shirin, A., Ferdous, J., Parag, R. R., Rahman, S. M., Mahmud, M. R., Jerin, C. S., Jahan, N., Siddiqua, A., Ara, T., Sabur, E. B., Alam, S. S., Baidya, S., Akther, S., Rahman, M. Z., Banu, T., Murugan, A. K., Sabri, S., Islam, S. M. S., Karakas, B., Aboussekhra, A., Yeger, H., Farhat, W. A., Islam, S. S.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.05.2017 Nature Publishing Group Nature Portfolio
Subjects:	13 13/21 13/31 14 14/1 14/105 14/19 38 38/91 631/67/1347 631/67/1857 Biomarkers Biomarkers, Tumor Bone Neoplasms - secondary Breast cancer Breast Neoplasms - blood Breast Neoplasms - diagnosis Breast Neoplasms - mortality Case-Control Studies Disease Progression Female Hedgehog protein Hedgehog Proteins - blood Humanities and Social Sciences Humans Immunoassays Interleukin 6 Interleukin-6 - blood Lymph nodes Metastases Metastasis multidisciplinary Neoplasm Metastasis Neoplasm Staging Prognosis ROC Curve Science Science (multidisciplinary) Serum levels Statistical analysis Survival Whole Body Imaging
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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