Evidences for lipid involvement in SARS-CoV-2 cytopathogenesis

The pathogenesis of SARS-CoV-2 remains to be completely understood, and detailed SARS-CoV-2 cellular cytopathic effects requires definition. We performed a comparative ultrastructural study of SARS-CoV-1 and SARS-CoV-2 infection in Vero E6 cells and in lungs from deceased COVID-19 patients. SARS-CoV...

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Bibliographic Details
Published in:	Cell death & disease Vol. 12; no. 3; pp. 263 - 12
Main Authors:	Nardacci, Roberta, Colavita, Francesca, Castilletti, Concetta, Lapa, Daniele, Matusali, Giulia, Meschi, Silvia, Del Nonno, Franca, Colombo, Daniele, Capobianchi, Maria Rosaria, Zumla, Alimuddin, Ippolito, Giuseppe, Piacentini, Mauro, Falasca, Laura
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 12.03.2021 Springer Nature B.V Nature Publishing Group
Subjects:	13 13/51 14 14/1 14/19 14/28 14/63 692/420/254 692/699/255/2514 Animals Antibodies Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Chlorocebus aethiops Cholesterol Coronaviruses COVID-19 COVID-19 - metabolism COVID-19 - pathology Cytopathogenesis Cytopathogenic Effect, Viral Drug therapy Homeostasis Humans Immunology Life Sciences Lipid Droplets - ultrastructure Lipid Droplets - virology Lipid Metabolism Lipids Lung - metabolism Lung - ultrastructure Lung - virology Lungs Mitochondria Pathogenesis Pathogenicity Pneumocytes SARS-CoV-2 - metabolism SARS-CoV-2 - ultrastructure Severe Acute Respiratory Syndrome - metabolism Severe Acute Respiratory Syndrome - pathology Severe acute respiratory syndrome coronavirus 2 Severe acute respiratory syndrome-related coronavirus - metabolism Severe acute respiratory syndrome-related coronavirus - ultrastructure Vacuoles Vero Cells
ISSN:	2041-4889, 2041-4889
Online Access:	Get full text
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