Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health

Preterm birth (PTB) is associated with increased risk of type 2 diabetes and neurocognitive impairment later in life. We analyzed for the first time the associations of PTB with blood miRNA levels in adulthood. We also investigated the relationship of PTB associated miRNAs and adulthood phenotypes p...

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Vydané v:	Scientific reports Ročník 11; číslo 1; s. 9203 - 12
Hlavní autori:	Marttila, Saara, Rovio, Suvi, Mishra, Pashupati P., Seppälä, Ilkka, Lyytikäinen, Leo-Pekka, Juonala, Markus, Waldenberger, Melanie, Oksala, Niku, Ala-Korpela, Mika, Harville, Emily, Hutri-Kähönen, Nina, Kähönen, Mika, Raitakari, Olli, Lehtimäki, Terho, Raitoharju, Emma
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 28.04.2021 Nature Publishing Group Nature Portfolio
Predmet:	631/208/199 631/208/200 631/337/384/331 692/699/2743/137/773 Actin Adolescent Adult Adults Alzheimer's disease Attention Biomarkers - blood Birth weight Blood Blood levels Child Child, Preschool Cognition Cognitive ability Cognitive Dysfunction - blood Cognitive Dysfunction - epidemiology Cognitive Dysfunction - genetics Cytoskeleton Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Female Finland - epidemiology Follow-Up Studies Gene expression Gene Expression Profiling Genomes Gestational age Humanities and Social Sciences Humans Infant, Newborn Information processing Insulin Lipoproteins (very low density) Male Metabolic Diseases - blood Metabolic Diseases - epidemiology Metabolic Diseases - genetics Metabolomics MicroRNAs MicroRNAs - genetics Middle Aged miRNA Movement disorders multidisciplinary Neurodegenerative diseases Parkinson's disease Phenotypes Pregnancy Premature birth Premature Birth - physiopathology Prognosis Science Science (multidisciplinary) Serum levels Signal Transduction Visual perception Finland
ISSN:	2045-2322, 2045-2322
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