Persistent metabolic changes in HIV-infected patients during the first year of combination antiretroviral therapy

The HIV-human metabolic relationship is a complex interaction convoluted even more by antiretroviral therapy (cART) and comorbidities. The ability of cART to undo the HIV induced metabolic dysregulation is unclear and under-investigated. Using targeted metabolomics and multiplex immune biomarker ana...

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Bibliographic Details
Published in:	Scientific reports Vol. 8; no. 1; pp. 16947 - 11
Main Authors:	Peltenburg, N. Chantal, Schoeman, Johannes C., Hou, Jun, Mora, Fernando, Harms, Amy C., Lowe, Selwyn H., Bierau, Jörgen, Bakker, Jaap A., Verbon, Annelies, Hankemeier, Thomas, Boonstra, Andre
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16.11.2018 Nature Publishing Group
Subjects:	631/250/255/1901 631/45/320 692/53/2422 96/21 Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Drug therapy HIV Human immunodeficiency virus Humanities and Social Sciences Infections IP-10 protein Lipid metabolism Metabolic pathways Metabolism Metabolomics Monocyte chemoattractant protein 1 multidisciplinary Phospholipids Science Science (multidisciplinary) Triglycerides Tryptophan Triglyceride Species HIV-associated Neurocognitive Disorders (HAND) Paired Patient Samples Plasmalogen Phosphatidylcholine (PC-O) Metabolic Dysregulation
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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