Innate immunity: the first line of defense against SARS-CoV-2

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity and mortality. While most infections are mild, some patients experience severe and potentially fatal systemic inflammation, tissue damage,...

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Bibliographic Details
Published in:	Nature immunology Vol. 23; no. 2; pp. 165 - 176
Main Authors:	Diamond, Michael S, Kanneganti, Thirumala-Devi
Format:	Journal Article
Language:	English
Published:	United States Nature Publishing Group 01.02.2022
Subjects:	Animals Coronaviruses COVID-19 COVID-19 - immunology COVID-19 - metabolism COVID-19 - virology Cytokine storm Cytokines Cytokines - immunology Cytokines - metabolism Humans Immune clearance Immune Evasion Immune system Immunity, Innate Inflammasomes - immunology Inflammasomes - metabolism Inflammation Innate immunity Morbidity NLR Proteins - immunology NLR Proteins - metabolism Pandemics Pattern recognition Pattern recognition receptors Receptors, Pattern Recognition - immunology Receptors, Pattern Recognition - metabolism Respiratory distress syndrome SARS-CoV-2 - immunology SARS-CoV-2 - pathogenicity Severe acute respiratory syndrome coronavirus 2 Signal Transduction Toll-Like Receptors - immunology Toll-Like Receptors - metabolism Virus Internalization
ISSN:	1529-2908, 1529-2916, 1529-2916
Online Access:	Get full text
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