Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

Transposable elements (TEs) make up a majority of a typical eukaryote’s genome, and contribute to cell heterogeneity in unclear ways. Single-cell sequencing technologies are powerful tools to explore cells, however analysis is typically gene-centric and TE expression has not been addressed. Here, we...

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Veröffentlicht in:Nature communications Jg. 12; H. 1; S. 1456 - 14
Hauptverfasser: He, Jiangping, Babarinde, Isaac A., Sun, Li, Xu, Shuyang, Chen, Ruhai, Shi, Junjie, Wei, Yuanjie, Li, Yuhao, Ma, Gang, Zhuang, Qiang, Hutchins, Andrew P., Chen, Jiekai
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 05.03.2021
Nature Publishing Group
Nature Portfolio
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ISSN:2041-1723, 2041-1723
Online-Zugang:Volltext
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