Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

Transposable elements (TEs) make up a majority of a typical eukaryote’s genome, and contribute to cell heterogeneity in unclear ways. Single-cell sequencing technologies are powerful tools to explore cells, however analysis is typically gene-centric and TE expression has not been addressed. Here, we...

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Bibliographic Details
Published in:	Nature communications Vol. 12; no. 1; pp. 1456 - 14
Main Authors:	He, Jiangping, Babarinde, Isaac A., Sun, Li, Xu, Shuyang, Chen, Ruhai, Shi, Junjie, Wei, Yuanjie, Li, Yuhao, Ma, Gang, Zhuang, Qiang, Hutchins, Andrew P., Chen, Jiekai
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 05.03.2021 Nature Publishing Group Nature Portfolio
Subjects:	13/100 38/91 631/136/142 631/1647/48 631/61/514/1949 Animals Cell fate Chromatin DNA Transposable Elements - genetics Embryo cells Embryogenesis Embryonic growth stage Embryonic Stem Cells Gastrulation Gene expression Gene Expression Regulation, Developmental Genetic Heterogeneity Genomes Heterogeneity Humanities and Social Sciences Humans Mice multidisciplinary Organogenesis - genetics Pipelines Pluripotency Science Science (multidisciplinary) Single-Cell Analysis - methods Somatic cells Stem cells Subpopulations Transposons
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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