Function and therapeutic value of astrocytes in neurological diseases

Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse functions in health and disease. Astrocyte dysfunction is found in numerous diseases, including multiple sclerosis, Alzheimer disease, Parkinson disease, Huntington disease and neuropsychiatric disorders. As...

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Bibliographic Details
Published in:	Nature reviews. Drug discovery Vol. 21; no. 5; pp. 339 - 358
Main Authors:	Lee, Hong-Gyun, Wheeler, Michael A, Quintana, Francisco J
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.05.2022
Subjects:	Astrocytes - metabolism Cell Communication Cytokines DNA methylation Epigenetics Glutamic Acid - metabolism Homeostasis Humans Huntingtons disease Inflammation Metabolism Morphology Multiple Sclerosis Nervous system Nervous System Diseases - metabolism Nervous System Diseases - therapy Neurodegeneration Neurons Parkinson's disease Pathogenesis Permeability
ISSN:	1474-1776, 1474-1784, 1474-1784
Online Access:	Get full text
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