Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations

Introduction Development of clinical biomarkers to guide therapy is an important unmet need in aneurysmal subarachnoid hemorrhage (SAH). A wide spectrum of plausible biomarkers has been reported for SAH, but none have been validated due to significant variabilities in study design, methodology, labo...

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Bibliographic Details
Published in:	Neurocritical care Vol. 30; no. Suppl 1; pp. 46 - 59
Main Authors:	Chou, Sherry H.-Y., Macdonald, R. Loch, Keller, Emanuela
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.06.2019 Springer Nature B.V
Subjects:	Aneurysm, Ruptured - complications Aneurysm, Ruptured - metabolism Aneurysms Biomarkers Biomarkers - metabolism Biomedical Research Brain Ischemia - etiology Brain Ischemia - metabolism Catheters Common Data Elements Critical Care Medicine Disease Experimental methods Humans Intensive Internal Medicine Intracranial Aneurysm - metabolism Medicine Medicine & Public Health Microdialysis Mortality National Institute of Neurological Disorders and Stroke (U.S.) National Library of Medicine (U.S.) Nervous system Neurology Oncology Prognosis Special Article Specimen Handling Stroke Subarachnoid Hemorrhage - complications Subarachnoid Hemorrhage - metabolism United States Validity Vasospasm, Intracranial - etiology Vasospasm, Intracranial - metabolism United States Biospecimens Plasma-type gelsolin Cardiac troponin I B-type natriuretic peptide, common data elements Standard operating procedure Subarachnoid hemorrhage Apolipoprotein E Biomarkers Cerebrospinal fluid S100β Tumor necrosis factor alpha, interleukin-6, metalloproteinase-9
ISSN:	1541-6933, 1556-0961, 1556-0961
Online Access:	Get full text
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