HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells

DNA damage is a prominent biomarker for numerous diseases, including cancer, as well as for the aging process. Detection of DNA damage routinely relies on traditional microscopy or cytometric methods. However, these techniques are typically of limited throughput and are not ideally suited for large-...

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Bibliographic Details
Published in:	Scientific reports Vol. 12; no. 1; pp. 6335 - 13
Main Authors:	Gallant, Kelsey, Bektas, Arsun, Kaileh, Mary, Lustig, Ana, Ferrucci, Luigi, Pegoraro, Gianluca, Misteli, Tom
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 15.04.2022 Nature Publishing Group Nature Portfolio
Subjects:	631/80/103 631/80/2373 Aging Batch processing Biological Assay CD4 antigen CD8 antigen Cryopreservation Deoxyribonucleic acid Diagnostic Imaging DNA DNA Damage High-Throughput Screening Assays - methods Humanities and Social Sciences Humans Lymphocytes B Lymphocytes T Monocytes multidisciplinary Population studies Science Science (multidisciplinary)
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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