Interferon-α2 Auto-antibodies in Convalescent Plasma Therapy for COVID-19

Purpose To study the effect of interferon-α2 auto-antibodies (IFN-α2 Abs) on clinical and virological outcomes in critically ill COVID-19 patients and the risk of IFN-α2 Abs transfer during convalescent plasma treatment. Methods Sera from healthy controls, cases of COVID-19, and other respiratory il...

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Bibliographic Details
Published in:	Journal of clinical immunology Vol. 42; no. 2; pp. 232 - 239
Main Authors:	Raadsen, Matthijs P., Gharbharan, Arvind, Jordans, Carlijn C. E., Mykytyn, Anna Z., Lamers, Mart M., van den Doel, Petra B., Endeman, Henrik, van den Akker, Johannes P. C., GeurtsvanKessel, Corine H., Koopmans, Marion P. G., Rokx, Casper, Goeijenbier, Marco, van Gorp, Eric C. M., Rijnders, Bart J. A., Haagmans, Bart L.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.02.2022 Springer Nature B.V
Subjects:	Adult Aged Antibodies, Neutralizing - immunology Antibodies, Viral - immunology Antiviral Agents - immunology Autoantibodies Autoantibodies - immunology Biomedical and Life Sciences Biomedicine Blood Component Transfusion - methods Coronaviruses COVID-19 COVID-19 - immunology COVID-19 - therapy COVID-19 Serotherapy Critical Illness Enzyme-linked immunosorbent assay Female Humans Immunization, Passive - methods Immunoglobulin G - immunology Immunology Infectious Diseases Interferon Interferon alpha-2 - immunology Internal Medicine Male Medical Microbiology Middle Aged Original Original Article Patients Plasma Plasma - immunology Respiratory diseases Respiratory tract SARS-CoV-2 - immunology COVID-19 SARS-CoV-2 Convalescent plasma Auto-antibodies Interferon alpha
ISSN:	0271-9142, 1573-2592, 1573-2592
Online Access:	Get full text
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