High-resolution label-free 3D mapping of extracellular pH of single living cells

Dynamic mapping of extracellular pH (pHe) at the single-cell level is critical for understanding the role of H + in cellular and subcellular processes, with particular importance in cancer. While several pHe sensing techniques have been developed, accessing this information at the single-cell level...

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Veröffentlicht in:	Nature communications Jg. 10; H. 1; S. 5610 - 9
Hauptverfasser:	Zhang, Yanjun, Takahashi, Yasufumi, Hong, Sung Pil, Liu, Fengjie, Bednarska, Joanna, Goff, Philip S., Novak, Pavel, Shevchuk, Andrew, Gopal, Sahana, Barozzi, Iros, Magnani, Luca, Sakai, Hideki, Suguru, Yoshimoto, Fujii, Takuto, Erofeev, Alexander, Gorelkin, Peter, Majouga, Alexander, Weiss, Dominik J., Edwards, Christopher, Ivanov, Aleksandar P., Klenerman, David, Sviderskaya, Elena V., Edel, Joshua B., Korchev, Yuri
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 06.12.2019 Nature Publishing Group Nature Portfolio
Schlagworte:	13 14 14/10 631/57/2265 631/57/2282 639/638 639/925 Barrel plating Biophysics Breast cancer Cancer Cell Line, Tumor Conductance Diatoms - cytology Heterogeneity Humanities and Social Sciences Humans Hydrogen-Ion Concentration Imaging, Three-Dimensional - methods Mapping Melanoma Microscopy, Electron, Scanning multidisciplinary Neoplasms - diagnostic imaging Neoplasms - pathology pH effects Response time Science Science (multidisciplinary) Sensitivity Single-Cell Analysis - methods Spatial resolution Temporal resolution Tumors
ISSN:	2041-1723, 2041-1723
Online-Zugang:	Volltext
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