SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19

Long-term antibody responses and neutralizing activities in response to SARS-CoV-2 infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies recognizing the SARS-CoV-2 receptor-binding domain (RBD) of the spike (S) or the nucleocapsid (N) protein, and neutralizing a...

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Bibliographic Details
Published in:	Nature communications Vol. 12; no. 1; pp. 1813 - 9
Main Authors:	Wu, Jun, Liang, Boyun, Chen, Cunrong, Wang, Hua, Fang, Yaohui, Shen, Shu, Yang, Xiaoli, Wang, Baoju, Chen, Liangkai, Chen, Qi, Wu, Yang, Liu, Jia, Yang, Xuecheng, Li, Wei, Zhu, Bin, Zhou, Wenqing, Wang, Huan, Li, Sumeng, Lu, Sihong, Liu, Di, Li, Huadong, Krawczyk, Adalbert, Lu, Mengji, Yang, Dongliang, Deng, Fei, Dittmer, Ulf, Trilling, Mirko, Zheng, Xin
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 22.03.2021 Nature Publishing Group Nature Portfolio
Subjects:	13/1 631/250/2152/2153/1291 631/326/596/4130 692/699/255/2514 Adult Aged Antibodies Antibodies, Neutralizing - immunology Antibodies, Viral - immunology Binding Contraction Coronaviruses COVID-19 COVID-19 - immunology Female Humanities and Social Sciences Humans Humoral immunity Immune response Immune response (humoral) Immunity Immunity, Humoral - immunology Immunoglobulin G Immunoglobulin G - immunology Immunoglobulin M Immunoglobulin M - immunology Male Middle Aged multidisciplinary Neutralizing Nucleocapsids SARS-CoV-2 - immunology Science Science (multidisciplinary) Severe acute respiratory syndrome coronavirus 2 Severity of Illness Index Spike Glycoprotein, Coronavirus Spikes Viral diseases
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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