A coordinated progression of progenitor cell states initiates urinary tract development

The kidney and upper urinary tract develop through reciprocal interactions between the ureteric bud and the surrounding mesenchyme. Ureteric bud branching forms the arborized collecting duct system of the kidney, while ureteric tips promote nephron formation from dedicated progenitor cells. While ne...

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Bibliographic Details
Published in:	Nature communications Vol. 12; no. 1; pp. 2627 - 16
Main Authors:	Sanchez-Ferras, Oraly, Pacis, Alain, Sotiropoulou, Maria, Zhang, Yuhong, Wang, Yu Chang, Bourgey, Mathieu, Bourque, Guillaume, Ragoussis, Jiannis, Bouchard, Maxime
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.05.2021 Nature Publishing Group Nature Portfolio
Subjects:	13/31 13/51 14/19 38/91 631/114 631/136/142 631/136/2060 631/80 Animals AP-2 protein Cell Differentiation - genetics Cells (biology) Clusters Collecting duct Developmental disabilities Embryo, Mammalian Embryos Female GATA-3 protein GATA3 Transcription Factor - metabolism Gene Expression Regulation, Developmental Humanities and Social Sciences Kidneys Male Mesenchyme Mesoderm Mice Mice, Transgenic Models, Animal Morphogenesis multidisciplinary Nephrons - embryology Organogenesis - genetics Populations Progenitor cells Ribonucleic acid RNA RNA-Seq Science Science (multidisciplinary) Single-Cell Analysis Stem cells Stem Cells - physiology Tips Transcription Factor AP-2 - metabolism Transcription factors Ureter Urinary tract Urogenital system
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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