Changing sex for selfish gain: B chromosomes of Lake Malawi cichlid fish

B chromosomes are extra, non-essential chromosomes present in addition to the normal complement of A chromosomes. Many species of cichlid fish in Lake Malawi carry a haploid, female-restricted B chromosome. Here we show that this B chromosome exhibits drive, with an average transmission rate of 70%....

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Veröffentlicht in:Scientific reports Jg. 9; H. 1; S. 20213 - 10
Hauptverfasser: Clark, Frances E., Kocher, Thomas D.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 27.12.2019
Nature Publishing Group
Schlagworte:
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Animals
B chromosome
Chromosomes
Cichlids - genetics
Evolution, Molecular
Female
Females
Genotyping
Haploidy
Humanities and Social Sciences
Lakes
Malawi
Male
Meiosis
Meiotic drive
multidisciplinary
Offspring
Science
Science (multidisciplinary)
Sex chromosomes
Sex Chromosomes - genetics
Sex Determination Analysis - methods
Sex Determination Processes - genetics
Sex Ratio
Malawi
Lake Malawi
ISSN:2045-2322, 2045-2322
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:B chromosomes are extra, non-essential chromosomes present in addition to the normal complement of A chromosomes. Many species of cichlid fish in Lake Malawi carry a haploid, female-restricted B chromosome. Here we show that this B chromosome exhibits drive, with an average transmission rate of 70%. The offspring of B-transmitting females exhibit a strongly female-biased sex ratio. Genotyping of these offspring reveals the B chromosome carries a female sex determiner that is epistatically dominant to an XY system on linkage group 7. We suggest that this sex determiner evolved to enhance the meiotic drive of the B chromosome. This is some of the first evidence that female meiotic drive can lead to the invasion of new sex chromosomes solely to benefit the driver, and not to compensate for skewed sex ratios.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-55774-8