Targeting C‐type lectin receptors: a high‐carbohydrate diet for dendritic cells to improve cancer vaccines

Review of in vivo targeting of tumor antigens to lectin receptors on antigen‐presenting cells using antibodies or ligands may improve the antitumor efficacy of vaccines. There is a growing understanding of why certain patients do or do not respond to checkpoint inhibition therapy. This opens new opp...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 102; no. 4; pp. 1017 - 1034
Main Authors:	Dinther, Dieke, Stolk, Dorian A., Ven, Rieneke, Kooyk, Yvette, Gruijl, Tanja D., Haan, Joke M. M.
Format:	Journal Article
Language:	English
Published:	Bethesda, MD, USA Society for Leukocyte Biology 01.10.2017 Oxford University Press
Subjects:	Animals Antibodies Anticancer properties Antigen (tumor-associated) antigen presentation Antigen-presenting cells Antigens Antitumor activity Cancer Cancer vaccines Cancer Vaccines - genetics Cancer Vaccines - immunology Cancer Vaccines - therapeutic use Carbohydrates Cytotoxicity Dendritic cells Dendritic Cells - immunology Humans Immune checkpoint Immune response Immune system Immunotherapy Lectins Lectins, C-Type - genetics Lectins, C-Type - immunology Lymphocytes Lymphocytes T Macrophages Neoplasms - genetics Neoplasms - immunology Neoplasms - therapy Priming Receptors Reviews T cell receptors T cells T-Lymphocytes, Helper-Inducer - immunology Vaccines macrophages antigen presentation T cells antigen presenting cells
ISSN:	0741-5400, 1938-3673, 1938-3673
Online Access:	Get full text
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