Histone variants — ancient wrap artists of the epigenome

Key Points Canonical histones H2A, H2B, H3 and H4 wrap DNA to form nucleosome particles that compact the genome. Histone variants have diverse additional roles in chromosome metabolism and can differ from canonical histones in stability, DNA wrapping and specialized domains. The 'universal'...

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Bibliographic Details
Published in:	Nature reviews. Molecular cell biology Vol. 11; no. 4; pp. 264 - 275
Main Authors:	Talbert, Paul B., Henikoff, Steven
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.04.2010 Nature Publishing Group
Subjects:	631/337/100/102 631/337/100/1701 631/337/100/2286 631/535 Animals Biochemistry Biomedical and Life Sciences Cancer Research Cell Biology Chromosomes Deoxyribonucleic acid Developmental Biology DNA DNA binding proteins DNA Repair DNA replication Epigenesis, Genetic Evolution Genes Genetic Variation Genomes Histones Histones - genetics Humans Life Sciences Packaging Physiological aspects Protein Processing, Post-Translational Proteins review-article Sperm Stem Cells
ISSN:	1471-0072, 1471-0080, 1471-0080
Online Access:	Get full text
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