Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study

Background Artemisinin resistance in Plasmodium falciparum extends across Southeast Asia where it is associated with worsening partner drug resistance and a decline in the efficacy of frontline artemisinin-based combination therapy. Dihydroartemisinin-piperaquine (DP) is an essential component of pr...

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Veröffentlicht in:	Malaria journal Jg. 15; H. 1; S. 185
Hauptverfasser:	Tun, Kyaw Myo, Jeeyapant, Atthanee, Imwong, Mallika, Thein, Min, Aung, Sai Soe Moe, Hlaing, Tin Maung, Yuentrakul, Prayoon, Promnarate, Cholrawee, Dhorda, Mehul, Woodrow, Charles J., Dondorp, Arjen M., Ashley, Elizabeth A., Smithuis, Frank M., White, Nicholas J., Day, Nicholas P. J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 31.03.2016 BioMed Central Ltd Springer Nature B.V
Schlagworte:	Administration, Oral Adolescent Adult Aged Analysis Antimalarials - therapeutic use Artemisinins - therapeutic use Biomedical and Life Sciences Biomedicine Care and treatment Child Child, Preschool Dosage and administration Drug Resistance Entomology Female Genotypes Health aspects Humans Infant Infectious Diseases Malaria Malaria, Falciparum - drug therapy Malaria, Falciparum - parasitology Male Microbiology Middle Aged Mutation Mutation, Missense Myanmar Parasitemia - drug therapy Parasitemia - parasitology Parasites Parasitology Plasmodium falciparum Primaquine Prospective Studies Protozoan Proteins - genetics Public Health Quinolines - therapeutic use Tropical Medicine Vector-borne diseases Young Adult Myanmar Cambodia China Artemisinin resistance Myanmar Parasite clearance half-life Kelch 13 propeller Plasmodium falciparum
ISSN:	1475-2875, 1475-2875
Online-Zugang:	Volltext
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