Anatomical-Based Filler Injection Diagnosis to Treatment Techniques: Infraorbital Groove and Hollowness

Infraorbital groove and hollowness are common aging-related anatomical changes in the periorbital region, leading to a sunken and tired appearance. These conditions are caused by the progressive loss of volume in the deep fat pads, including the sub-orbicularis oculi fat (SOOF) and malar fat, along...

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Published in:	Life (Basel, Switzerland) Vol. 15; no. 2; p. 237
Main Authors:	Hong, Gi-Woong, Choi, Wonseok, Yoon, Song-Eun, Wan, Jovian, Yi, Kyu-Ho
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01.02.2025 MDPI
Subjects:	Aging dermal fillers Diagnosis Evidence-based medicine facial aging Fillers Grooves Hyaluronic acid Infraorbital region Injection Ligaments Methods Review tear trough White people South Korea tear trough facial aging Infraorbital region dermal fillers hyaluronic acid
ISSN:	2075-1729, 2075-1729
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Abstract	Infraorbital groove and hollowness are common aging-related anatomical changes in the periorbital region, leading to a sunken and tired appearance. These conditions are caused by the progressive loss of volume in the deep fat pads, including the sub-orbicularis oculi fat (SOOF) and malar fat, along with skin thinning and decreased elasticity. Filler injections, particularly hyaluronic acid-based fillers, are the preferred treatment to restore volume and smooth the under-eye area. Proper diagnosis, understanding of anatomical variations, and accurate injection techniques are essential to avoid complications and achieve natural, esthetically pleasing outcomes. Treatments should consider the patient’s unique anatomy and potential adjunctive procedures to ensure balanced and harmonious facial rejuvenation.
AbstractList	Infraorbital groove and hollowness are common aging-related anatomical changes in the periorbital region, leading to a sunken and tired appearance. These conditions are caused by the progressive loss of volume in the deep fat pads, including the sub-orbicularis oculi fat (SOOF) and malar fat, along with skin thinning and decreased elasticity. Filler injections, particularly hyaluronic acid-based fillers, are the preferred treatment to restore volume and smooth the under-eye area. Proper diagnosis, understanding of anatomical variations, and accurate injection techniques are essential to avoid complications and achieve natural, esthetically pleasing outcomes. Treatments should consider the patient’s unique anatomy and potential adjunctive procedures to ensure balanced and harmonious facial rejuvenation. Infraorbital groove and hollowness are common aging-related anatomical changes in the periorbital region, leading to a sunken and tired appearance. These conditions are caused by the progressive loss of volume in the deep fat pads, including the sub-orbicularis oculi fat (SOOF) and malar fat, along with skin thinning and decreased elasticity. Filler injections, particularly hyaluronic acid-based fillers, are the preferred treatment to restore volume and smooth the under-eye area. Proper diagnosis, understanding of anatomical variations, and accurate injection techniques are essential to avoid complications and achieve natural, esthetically pleasing outcomes. Treatments should consider the patient's unique anatomy and potential adjunctive procedures to ensure balanced and harmonious facial rejuvenation.Infraorbital groove and hollowness are common aging-related anatomical changes in the periorbital region, leading to a sunken and tired appearance. These conditions are caused by the progressive loss of volume in the deep fat pads, including the sub-orbicularis oculi fat (SOOF) and malar fat, along with skin thinning and decreased elasticity. Filler injections, particularly hyaluronic acid-based fillers, are the preferred treatment to restore volume and smooth the under-eye area. Proper diagnosis, understanding of anatomical variations, and accurate injection techniques are essential to avoid complications and achieve natural, esthetically pleasing outcomes. Treatments should consider the patient's unique anatomy and potential adjunctive procedures to ensure balanced and harmonious facial rejuvenation.
Audience	Academic
Author	Yoon, Song-Eun Hong, Gi-Woong Choi, Wonseok Wan, Jovian Yi, Kyu-Ho
AuthorAffiliation	1 Samskin Plastic Surgery Clinic, Seoul, Republic of Korea 2 V Plastic Surgery, Daegu, Republic of Korea 6 You & I Clinic (Mokdong), Seoul, Republic of Korea 5 Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, College of Dentistry, Yonsei University, Seoul 03722, Republic of Korea 4 Medical Research, Wonju, Republic of Korea 3 Brandnew Aesthetic Surgery Clinic, Seoul, Republic of Korea
AuthorAffiliation_xml	– name: 1 Samskin Plastic Surgery Clinic, Seoul, Republic of Korea – name: 3 Brandnew Aesthetic Surgery Clinic, Seoul, Republic of Korea – name: 2 V Plastic Surgery, Daegu, Republic of Korea – name: 4 Medical Research, Wonju, Republic of Korea – name: 6 You & I Clinic (Mokdong), Seoul, Republic of Korea – name: 5 Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, College of Dentistry, Yonsei University, Seoul 03722, Republic of Korea
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Cites_doi	10.1097/PRS.0b0133182a0539e 10.1111/jocd.13705 10.1097/SCS.0b013e3182418e63 10.1097/PRS.0b013e3182362b96 10.1097/SCS.0000000000001617 10.1097/GOX.0000000000003559 10.1097/PRS.0b013e31824ecd77 10.1097/PRS.0000000000008964 10.1054/ijom.2002.0372 10.1097/PRS.0b013e31819f2b36 10.1016/j.det.2023.06.013 10.5115/acb.23.275 10.1007/s00276-023-03265-x 10.1055/s-0041-1731348 10.1007/s00266-013-0109-1 10.1093/asjof/ojad016 10.1007/s00276-016-1683-0 10.1038/s41598-018-35425-0 10.1097/PRS.0000000000003716 10.1111/jocd.13089 10.1111/jocd.13245 10.3390/medicina59081479 10.1097/GOX.0000000000005327 10.1097/PRS.0000000000008716 10.4103/0974-2077.184046 10.1097/00001665-200203000-00003 10.1016/j.jormas.2017.06.014 10.1097/DSS.0000000000001056 10.1097/01.prs.0000299941.62645.4e 10.1111/jocd.12514 10.1097/01.prs.0000279558.86727.5a 10.5114/ada.2016.61607 10.4103/0974-2077.104910 10.1097/DSS.0000000000003000 10.1055/s-2003-40007 10.1111/dth.12448 10.5999/aps.2017.01193 10.1111/srt.13511 10.1097/PRS.0000000000002346
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References	Flynn (ref_9) 2001; 27 Freeman (ref_27) 2003; 19 Ercikti (ref_10) 2017; 39 Hwang (ref_15) 2015; 26 Park (ref_21) 2012; 23 Nikolis (ref_33) 2022; 21 Woodward (ref_1) 2023; 5 Joganathan (ref_4) 2021; 20 Turkmani (ref_19) 2017; 43 Ghavami (ref_29) 2008; 121 Peng (ref_32) 2018; 17 Chen (ref_18) 2022; 149 Casabona (ref_28) 2020; 19 Jiang (ref_12) 2016; 33 Spada (ref_30) 2023; 11 Lee (ref_5) 2024; 57 Li (ref_36) 2023; 29 Yang (ref_11) 2013; 132 Koh (ref_23) 2003; 32 Chatel (ref_42) 2017; 118 Hwang (ref_26) 2002; 13 DeBoulle (ref_41) 2017; 140 Lee (ref_8) 2018; 45 Trinh (ref_16) 2022; 38 Haddock (ref_17) 2009; 123 Casabona (ref_43) 2019; 18 Sharad (ref_31) 2012; 5 Lee (ref_7) 2024; 46 Bae (ref_45) 2016; 138 Gierloff (ref_39) 2012; 129 Song (ref_3) 2007; 120 ref_25 Russa (ref_34) 2013; 37 ref_24 ref_22 Vrcek (ref_2) 2016; 9 ref_20 Ho (ref_37) 2024; 42 Bouman (ref_38) 2021; 9 Wong (ref_13) 2012; 129 Liang (ref_35) 2016; 06 Cong (ref_14) 2021; 47 Duan (ref_40) 2022; 149 ref_6 Beer (ref_44) 2008; 7
References_xml	– volume: 132 start-page: 796 year: 2013 ident: ref_11 article-title: Tear trough and palpebromalar groove in young versus elderly adults: A sectional anatomy study publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0b0133182a0539e – volume: 20 start-page: 1214 year: 2021 ident: ref_4 article-title: Novel technique of non-surgical rejuvenation of infraorbital dark circles publication-title: J. Cosmet. Dermatol. doi: 10.1111/jocd.13705 – volume: 23 start-page: 195 year: 2012 ident: ref_21 article-title: Medial muscular band of the orbicularis oculi muscle publication-title: J. Craniofac. Surg. doi: 10.1097/SCS.0b013e3182418e63 – volume: 129 start-page: 263 year: 2012 ident: ref_39 article-title: Aging changes of the midfacial fat compartments: A computed tomographic study publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0b013e3182362b96 – volume: 26 start-page: 1389 year: 2015 ident: ref_15 article-title: Origin of the lower orbicularis oculi muscle in relation to the nasojugal groove publication-title: J. Craniofac. Surg. doi: 10.1097/SCS.0000000000001617 – volume: 27 start-page: 703 year: 2001 ident: ref_9 article-title: Botulinum-a toxin treatment of the lower eyelid improves infraorbital rhytides and widens the eye publication-title: Dermatol. Surg. – volume: 9 start-page: e3559 year: 2021 ident: ref_38 article-title: A new approach in the correction of the midcheek groove: The liquid malar-lift technique publication-title: Plast Reconstr. Surg. Glob Open doi: 10.1097/GOX.0000000000003559 – volume: 7 start-page: 359 year: 2008 ident: ref_44 article-title: Evaluation of injectable caha for the treatment of mid-face volume loss publication-title: J. Drugs Dermatol. – volume: 129 start-page: 1392 year: 2012 ident: ref_13 article-title: The tear trough ligament: Anatomical basis for the tear trough deformity publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0b013e31824ecd77 – volume: 149 start-page: 646e year: 2022 ident: ref_18 article-title: Anatomical characterization of the tear trough and the lid-cheek junction: An iodine staining technique based on high-resolution micro-computed tomography publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0000000000008964 – volume: 06 start-page: 1 year: 2016 ident: ref_35 article-title: A guide to cheek augmentation: Single-point deep injection of hyaluronic acid filler at midface in close proximity to medial suborbicularis oculi fat (soof) area publication-title: J. Cosmet. Dermatol. Sci. Appl. – volume: 32 start-page: 414 year: 2003 ident: ref_23 article-title: Branching patterns and symmetry of the course of the facial artery in koreans publication-title: Int. J. Oral. Maxillofac. Surg. doi: 10.1054/ijom.2002.0372 – volume: 123 start-page: 1332 year: 2009 ident: ref_17 article-title: The tear trough and lid/cheek junction: Anatomy and implications for surgical correction publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0b013e31819f2b36 – volume: 42 start-page: 113 year: 2024 ident: ref_37 article-title: Achieving the attractive asian midface profile with hyaluronic acid-based fillers publication-title: Dermatol. Clin. doi: 10.1016/j.det.2023.06.013 – volume: 57 start-page: 25 year: 2024 ident: ref_5 article-title: A novel histologic description of the fibrous networks in the lid-cheek junction and infraorbital region publication-title: Anat. Cell Biol. doi: 10.5115/acb.23.275 – volume: 46 start-page: 3 year: 2024 ident: ref_7 article-title: A novel description of the supporting system of the orbicularis oculi muscle in the infraorbital area: Tear trough muscle fiber publication-title: Surg. Radiol. Anat. doi: 10.1007/s00276-023-03265-x – volume: 38 start-page: 228 year: 2022 ident: ref_16 article-title: Dermal fillers for tear trough rejuvenation: A systematic review publication-title: Facial. Plast Surg. doi: 10.1055/s-0041-1731348 – volume: 37 start-page: 587 year: 2013 ident: ref_34 article-title: Hyaluronic acid filler injections for tear-trough deformity: Injection technique and high-frequency ultrasound follow-up evaluation publication-title: Aesthetic. Plast Surg. doi: 10.1007/s00266-013-0109-1 – volume: 5 start-page: ojad016 year: 2023 ident: ref_1 article-title: Infraorbital hollow rejuvenation: Considerations, complications, and the contributions of midface volumization publication-title: Aesthet. Surg. J. Open Forum. doi: 10.1093/asjof/ojad016 – volume: 39 start-page: 11 year: 2017 ident: ref_10 article-title: Location of the infraorbital foramen with reference to soft tissue landmarks publication-title: Surg. Radiol. Anat. doi: 10.1007/s00276-016-1683-0 – ident: ref_22 doi: 10.1038/s41598-018-35425-0 – volume: 140 start-page: 540e year: 2017 ident: ref_41 article-title: Facial assessment and injection guide for botulinum toxin and injectable hyaluronic acid fillers: Focus on the midface publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0000000000003716 – volume: 18 start-page: 1237 year: 2019 ident: ref_43 article-title: Lifting vs volumizing-the difference in facial minimally invasive procedures when respecting the line of ligaments publication-title: J. Cosmet. Dermatol. doi: 10.1111/jocd.13089 – volume: 19 start-page: 303 year: 2020 ident: ref_28 article-title: How to best utilize the line of ligaments and the surface volume coefficient in facial soft tissue filler injections publication-title: J. Cosmet. Dermatol. doi: 10.1111/jocd.13245 – ident: ref_25 – ident: ref_24 doi: 10.3390/medicina59081479 – volume: 11 start-page: e5327 year: 2023 ident: ref_30 article-title: Needle versus cannula to treat tear trough: A prospective study comparing both methods publication-title: Plast Reconstr. Surg. Glob Open doi: 10.1097/GOX.0000000000005327 – volume: 149 start-page: 198e year: 2022 ident: ref_40 article-title: Clarifying the anatomy of the zygomatic cutaneous ligament: Its application in midface rejuvenation publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0000000000008716 – volume: 9 start-page: 65 year: 2016 ident: ref_2 article-title: Infraorbital dark circles: A review of the pathogenesis, evaluation and treatment publication-title: J. Cutan Aesthet. Surg. doi: 10.4103/0974-2077.184046 – volume: 13 start-page: 202 year: 2002 ident: ref_26 article-title: Identity of “orbitozygomatic muscle” publication-title: J. Craniofac. Surg. doi: 10.1097/00001665-200203000-00003 – volume: 118 start-page: 283 year: 2017 ident: ref_42 article-title: Midface rejuvenation surgery combining preperiosteal midcheek lift, lower blepharoplasty with orbital fat preservation and autologous fat grafting publication-title: J. Stomatol. Oral. Maxillofac. Surg. doi: 10.1016/j.jormas.2017.06.014 – volume: 43 start-page: 836 year: 2017 ident: ref_19 article-title: New classification system for tear trough deformity publication-title: Dermatol. Surg. doi: 10.1097/DSS.0000000000001056 – volume: 21 start-page: 387 year: 2022 ident: ref_33 article-title: Expert recommendations on the use of hyaluronic acid filler for tear trough rejuvenation publication-title: J. Drugs Dermatol. – volume: 121 start-page: 994 year: 2008 ident: ref_29 article-title: The orbicularis retaining ligament of the medial orbit: Closing the circle publication-title: Plast Reconstr. Surg. doi: 10.1097/01.prs.0000299941.62645.4e – volume: 17 start-page: 333 year: 2018 ident: ref_32 article-title: Treating the tear trough: A new classification system, a 6-step evaluation procedure, hyaluronic acid injection algorithm, and treatment sequences publication-title: J. Cosmet. Dermatol. doi: 10.1111/jocd.12514 – volume: 120 start-page: 1343 year: 2007 ident: ref_3 article-title: Location of the infraorbital and mental foramen with reference to the soft-tissue landmarks publication-title: Plast Reconstr. Surg. doi: 10.1097/01.prs.0000279558.86727.5a – volume: 33 start-page: 303 year: 2016 ident: ref_12 article-title: Tear trough deformity: Different types of anatomy and treatment options publication-title: Postep. Dermatol. Alergol doi: 10.5114/ada.2016.61607 – volume: 5 start-page: 229 year: 2012 ident: ref_31 article-title: Dermal fillers for the treatment of tear trough deformity: A review of anatomy, treatment techniques, and their outcomes publication-title: J. Cutan Aesthet. Surg. doi: 10.4103/0974-2077.104910 – volume: 47 start-page: 785 year: 2021 ident: ref_14 article-title: Three-dimensional computed tomography of the detoured facial artery: Variations and implications for nasojugal groove correction publication-title: Dermatol. Surg. doi: 10.1097/DSS.0000000000003000 – volume: 19 start-page: 223 year: 2003 ident: ref_27 article-title: Rejuvenation of the midface publication-title: Facial Plast Surg. doi: 10.1055/s-2003-40007 – ident: ref_20 – ident: ref_6 doi: 10.1111/dth.12448 – volume: 45 start-page: 214 year: 2018 ident: ref_8 article-title: Definitions of groove and hollowness of the infraorbital region and clinical treatment using soft-tissue filler publication-title: Arch. Plast Surg. doi: 10.5999/aps.2017.01193 – volume: 29 start-page: e13511 year: 2023 ident: ref_36 article-title: U-type soft tissue lifting: A new composited technique for reversing lower eyelid and midfacial aging publication-title: Ski. Res. Technol. doi: 10.1111/srt.13511 – volume: 138 start-page: 365 year: 2016 ident: ref_45 article-title: Clinical implications of the extension of platysmal fibers on the middle and lower face publication-title: Plast Reconstr. Surg. doi: 10.1097/PRS.0000000000002346
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StartPage	237
SubjectTerms	Aging dermal fillers Diagnosis Evidence-based medicine facial aging Fillers Grooves Hyaluronic acid Infraorbital region Injection Ligaments Methods Review tear trough White people
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Title	Anatomical-Based Filler Injection Diagnosis to Treatment Techniques: Infraorbital Groove and Hollowness
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Volume	15
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