Window of opportunity clinical trial designs to study cancer metabolism

Window of opportunity trials exploit the ‘window’ of time after cancer diagnosis, typically prior to initiation of cancer therapy. In recent years this study design has become a more regular feature of drug development, as this ‘window’ provides an opportunity to carry out a thorough pharmacodynamic...

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Bibliographic Details
Published in:	British journal of cancer Vol. 122; no. 1; pp. 45 - 51
Main Authors:	Aroldi, Francesca, Lord, Simon R.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.01.2020 Nature Publishing Group
Subjects:	631/154 631/67 631/67/2327 Antidiabetics Biological activity Biomedical and Life Sciences Biomedicine Cancer Cancer Research Cancer therapies Clinical trials Clinical Trials as Topic - methods Drug development Drug metabolism Drug Repositioning - methods Drug Resistance Epidemiology Humans Metabolism Metabolomics Metformin Metformin - therapeutic use Mitochondria Molecular Medicine Neoplasms - drug therapy Neoplasms - metabolism Oncology Pharmacodynamics Research Design Review Review Article Time-to-Treatment Tumors
ISSN:	0007-0920, 1532-1827, 1532-1827
Online Access:	Get full text
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