Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis

Herpes simplex encephalitis can trigger autoimmune encephalitis that leads to neurological worsening. We aimed to assess the frequency, symptoms, risk factors, and outcomes of this complication. We did a prospective observational study and retrospective analysis. In the prospective observational par...

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Published in:	Lancet neurology Vol. 17; no. 9; pp. 760 - 772
Main Authors:	Armangue, Thaís, Spatola, Marianna, Vlagea, Alexandru, Mattozzi, Simone, Cárceles-Cordon, Marc, Martinez-Heras, Eloy, Llufriu, Sara, Muchart, Jordi, Erro, María Elena, Abraira, Laura, Moris, German, Monros-Giménez, Luis, Corral-Corral, Íñigo, Montejo, Carmen, Toledo, Manuel, Bataller, Luis, Secondi, Gabriela, Ariño, Helena, Martínez-Hernández, Eugenia, Juan, Manel, Marcos, Maria Angeles, Alsina, Laia, Saiz, Albert, Rosenfeld, Myrna R, Graus, Francesc, Dalmau, Josep, Aguilera-Albesa, Sergio, Amado-Puentes, Alfonso, Arjona-Padillo, Antonio, Arrabal, Luisa, Arratibel, Izascun, Aznar-Laín, Gemma, Bellas-Lamas, Paula, Bermejo, Teresa, Boyero-Durán, Sabas, Camacho, Ana, Campo, Andrea, Campos, Dulce, Cantarín-Extremera, Verónica, Carnero, Cristóbal, Conejo-Moreno, David, Dapena, Marta, Dacruz-Álvarez, David, Delgadillo-Chilavert, Verónica, Deyà, Angela, Estela-Herrero, Jordi, Felipe, Anna, Fernández-Cooke, Elisa, Fernández-Ramos, Joaquín, Fortuny, Claudia, García-Monco, Juan C, Gili, Teresa, González-Álvarez, Verónica, Guerri, Robert, Guillén, Sara, Hedrera-Fernández, Antonio, López, María, López-Laso, Eduardo, Lorenzo-Ruiz, María, Madruga, Marcos, Málaga-Diéguez, Ignacio, Martí-Carrera, Itxaso, Martínez-Lacasa, Xavier, Martín-Viota, Lucía, Martín Gil, Leticia, Martínez-González, María-Jesús, Moreira, Antia, Miranda-Herrero, María C, Monge, Lorena, Muñoz-Cabello, Beatriz, Navarro-Morón, Juan, Neth, Olaf, Noguera-Julian, Antoni, Nuñez-Enamorado, Noemí, Pomar, Virginia, Portillo-Cuenca, Juan C, Poyato, María, Prieto, Luis, Querol, Luis, Rodríguez-Rodríguez, Eloy, Sarria-Estrada, Silvana, Sierra, Concepción, Soler-Palacín, Pere, Soto-Insuga, Víctor, Toledo-Bravo, Laura, Tomás, Miguel, Torres-Torres, Carmen, Turón, Eulàlia, Zabalza, Ana
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.09.2018 Elsevier Limited Elsevier B.V
Subjects:	Adolescent Adult Age Aged Amnesia Animals Antibodies Antigens Apathy Autoantibodies - metabolism Autoimmune diseases Autoimmunitat Autoimmunity Child Child, Preschool Children Choreoathetosis Cohort Studies Consciousness Demography Dysphagia Encefalitis Encephalitis Encephalitis - cerebrospinal fluid Encephalitis - diagnostic imaging Encephalitis - epidemiology Encephalitis - etiology Encephalitis, Herpes Simplex - cerebrospinal fluid Encephalitis, Herpes Simplex - complications Encephalitis, Herpes Simplex - diagnostic imaging Encephalitis, Herpes Simplex - epidemiology Epilepsy Female Glutamate Decarboxylase - metabolism Glutamic acid receptors (ionotropic) Hashimoto Disease - cerebrospinal fluid Hashimoto Disease - diagnostic imaging Hashimoto Disease - epidemiology Hashimoto Disease - etiology Herpes Herpes simplex Herpes viruses Herpesvirus diseases Hippocampus - metabolism Hippocampus - pathology Humans Immunoglobulins Immunotherapy Infectious diseases Insomnia Magnetic Resonance Imaging Male Middle Aged N-Methyl-D-aspartic acid receptors Observational studies Patients Psychosis Rats Receptors, N-Methyl-D-Aspartate - immunology Regression analysis Risk Factors Seizures Statistics, Nonparametric Viral infections Young Adult
ISSN:	1474-4422, 1474-4465, 1474-4465
Online Access:	Get full text
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